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GENE CARD

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Gene Card

Best human hits

CUL1; CUL2; CUL3

Unique Gene ID

Cirobu.g00008686

Gene Model ID

KH2012:KH.C7.86

Location

KhC7:733853..747445

External Database Gene Card

External database links

2 results

Collections

Gateway full ORF

2 results

cima862853

Plate: VES65_J03

cien156249

Plate: VES94_K10

Gene collection 1 (N. Satoh)

2 results

cieg015m20

Plate: R1CiGC17n12

cieg057p22

Plate: R1CiGC24d22

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

10 results

IPR Term Analysis Definition
Cullin_N Pfam Cullin, N-terminal
Cullin_repeat-like_dom_sf SUPERFAMILY Cullin repeat-like-containing domain superfamily
Cullin_homology_sf SUPERFAMILY Cullin homology domain superfamily
Cullin_neddylation_domain Pfam Cullin protein, neddylation domain
Cullin_neddylation_domain SMART Cullin protein, neddylation domain
Cullin_CS ProSitePatterns Cullin, conserved site
WH-like_DNA-bd_sf Gene3D Winged helix-like DNA-binding domain superfamily
WH_DNA-bd_sf SUPERFAMILY Winged helix DNA-binding domain superfamily
Cullin_homology ProSiteProfiles Cullin homology domain
Cullin_homology SMART Cullin homology domain

GOSlim

42 results

GO Term Annotation Origin Type
G1/S transition of mitotic cell cycle Orthology biological process
G2/M transition of mitotic cell cycle Orthology biological process
Golgi membrane Blast cellular component
protein polyubiquitination Orthology biological process
ubiquitin-protein transferase activity Orthology molecular function
protein binding Orthology molecular function
nucleus Blast cellular component
nucleoplasm Orthology cellular component
nucleolus Blast cellular component
cytoplasm Blast cellular component
Golgi apparatus Blast cellular component
cytosol Orthology cellular component
apoptotic process Orthology biological process
cell proliferation Orthology biological process
negative regulation of cell proliferation Orthology biological process
membrane Blast cellular component
protein ubiquitination Orthology biological process
ubiquitin protein ligase binding Orthology molecular function
protein homodimerization activity Blast molecular function
protein heterodimerization activity Blast molecular function
extracellular exosome Blast cellular component
proteolysis Orthology biological process
cellular process Orthology biological process
cell Orthology cellular component
animal organ development Orthology biological process
anatomical structure morphogenesis Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cell-cell signaling Orthology biological process
intracellular part Orthology cellular component
macromolecular complex Orthology cellular component
transcription factor activity, sequence-specific DNA binding Orthology molecular function
intracellular signal transduction Orthology biological process
immune response Orthology biological process
cellular protein modification process Orthology biological process
cellular response to stress Orthology biological process
protein phosphorylation Orthology biological process
cytokine-mediated signaling pathway Orthology biological process
receptor binding Blast molecular function
microtubule Blast cellular component
cytoplasmic part Blast cellular component
cell projection part Blast cellular component
plasma membrane region Blast cellular component

GO (Orthology)

34 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
G1/S transition of mitotic cell cycle Hs biological process
G2/M transition of mitotic cell cycle Hs biological process
protein polyubiquitination Hs biological process
ubiquitin-protein transferase activity Hs molecular function
protein binding Hs molecular function
nucleoplasm Hs cellular component
cytosol Hs cellular component
ubiquitin-dependent protein catabolic process Hs biological process
protein monoubiquitination Hs biological process
cellular iron ion homeostasis Hs biological process
apoptotic process Hs biological process
cell cycle arrest Hs biological process
cell proliferation Hs biological process
negative regulation of cell proliferation Hs biological process
animal organ morphogenesis Hs biological process
SCF complex assembly Hs biological process
negative regulation of G2/M transition of mitotic cell cycle Hs biological process
viral process Hs biological process
Wnt signaling pathway Hs biological process
protein ubiquitination Hs biological process
SCF ubiquitin ligase complex Hs cellular component
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Hs biological process
cullin-RING ubiquitin ligase complex Hs cellular component
ubiquitin protein ligase binding Hs molecular function
NIK/NF-kappaB signaling Hs biological process
Fc-epsilon receptor signaling pathway Hs biological process
proteasome-mediated ubiquitin-dependent protein catabolic process Hs biological process
post-translational protein modification Hs biological process
T cell receptor signaling pathway Hs biological process
stress-activated MAPK cascade Hs biological process
ubiquitin protein ligase activity Hs molecular function
interleukin-1-mediated signaling pathway Hs biological process
intrinsic apoptotic signaling pathway Hs biological process
Parkin-FBXW7-Cul1 ubiquitin ligase complex Hs cellular component

GO (Blast)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
Golgi membrane Hs cellular component 343 5.70e-107
ubiquitin-protein transferase activity Hs molecular function 1147 0.0
Notch binding Hs molecular function 343 5.70e-107
protein binding Hs molecular function 1147 0.0
nucleus Hs cellular component 343 5.70e-107
nucleoplasm Hs cellular component 1147 0.0
nucleolus Hs cellular component 457 1.28e-150
cytoplasm Hs cellular component 343 5.70e-107
Golgi apparatus Hs cellular component 343 5.70e-107
polar microtubule Hs cellular component 343 5.70e-107
cytosol Hs cellular component 1147 0.0
membrane Hs cellular component 343 5.70e-107
SCF ubiquitin ligase complex Hs cellular component 1147 0.0
cyclin binding Hs molecular function 343 5.70e-107
VCB complex Hs cellular component 457 1.28e-150
POZ domain binding Hs molecular function 343 5.70e-107
cullin-RING ubiquitin ligase complex Hs cellular component 1147 0.0
Cul2-RING ubiquitin ligase complex Hs cellular component 457 1.28e-150
Cul3-RING ubiquitin ligase complex Hs cellular component 343 5.70e-107
ubiquitin protein ligase binding Hs molecular function 1147 0.0
sperm flagellum Hs cellular component 343 5.70e-107
protein homodimerization activity Hs molecular function 343 5.70e-107
protein heterodimerization activity Hs molecular function 343 5.70e-107
ubiquitin protein ligase activity Hs molecular function 1147 0.0
extracellular exosome Hs cellular component 343 5.70e-107
Parkin-FBXW7-Cul1 ubiquitin ligase complex Hs cellular component 1147 0.0

GO (InterProScan)

3 results

GO Term Analysis Type e-value
ubiquitin-dependent protein catabolic process Pfam biological process 3.9E-191
cullin-RING ubiquitin ligase complex ProSitePatterns cellular component
ubiquitin protein ligase binding Pfam molecular function 3.9E-191