Gene Card
Best human hits
CUL1; CUL2; CUL3
Unique Gene ID
Cirobu.g00008686
Gene Model ID
KH2012:KH.C7.86
Location
KhC7:733853..747445
Transcript Models and Sequences
KH2012:KH.C7.86.v1.B.SL1-2
KH2012:KH.C7.86.v1.B.SL2-2
KH2012:KH.C7.86.v2.A.SL1-1
KH2012:KH.C7.86.v2.A.SL2-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000006501 |
NCBI Reference Sequence | XM_002123456.3 |
cima862853
Plate: VES65_J03
cien156249
Plate: VES94_K10
cieg015m20
Plate: R1CiGC17n12
cieg057p22
Plate: R1CiGC24d22
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Cullin_N | Pfam | Cullin, N-terminal |
Cullin_repeat-like_dom_sf | SUPERFAMILY | Cullin repeat-like-containing domain superfamily |
Cullin_homology_sf | SUPERFAMILY | Cullin homology domain superfamily |
Cullin_neddylation_domain | Pfam | Cullin protein, neddylation domain |
Cullin_neddylation_domain | SMART | Cullin protein, neddylation domain |
Cullin_CS | ProSitePatterns | Cullin, conserved site |
WH-like_DNA-bd_sf | Gene3D | Winged helix-like DNA-binding domain superfamily |
WH_DNA-bd_sf | SUPERFAMILY | Winged helix DNA-binding domain superfamily |
Cullin_homology | ProSiteProfiles | Cullin homology domain |
Cullin_homology | SMART | Cullin homology domain |
GO Term | Annotation Origin | Type |
---|---|---|
G1/S transition of mitotic cell cycle | Orthology | biological process |
G2/M transition of mitotic cell cycle | Orthology | biological process |
Golgi membrane | Blast | cellular component |
protein polyubiquitination | Orthology | biological process |
ubiquitin-protein transferase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Blast | cellular component |
nucleoplasm | Orthology | cellular component |
nucleolus | Blast | cellular component |
cytoplasm | Blast | cellular component |
Golgi apparatus | Blast | cellular component |
cytosol | Orthology | cellular component |
apoptotic process | Orthology | biological process |
cell proliferation | Orthology | biological process |
negative regulation of cell proliferation | Orthology | biological process |
membrane | Blast | cellular component |
protein ubiquitination | Orthology | biological process |
ubiquitin protein ligase binding | Orthology | molecular function |
protein homodimerization activity | Blast | molecular function |
protein heterodimerization activity | Blast | molecular function |
extracellular exosome | Blast | cellular component |
proteolysis | Orthology | biological process |
cellular process | Orthology | biological process |
cell | Orthology | cellular component |
animal organ development | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
intracellular part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
intracellular signal transduction | Orthology | biological process |
immune response | Orthology | biological process |
cellular protein modification process | Orthology | biological process |
cellular response to stress | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
cytokine-mediated signaling pathway | Orthology | biological process |
receptor binding | Blast | molecular function |
microtubule | Blast | cellular component |
cytoplasmic part | Blast | cellular component |
cell projection part | Blast | cellular component |
plasma membrane region | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
Golgi membrane | Hs | cellular component | 343 | 5.70e-107 |
ubiquitin-protein transferase activity | Hs | molecular function | 1147 | 0.0 |
Notch binding | Hs | molecular function | 343 | 5.70e-107 |
protein binding | Hs | molecular function | 1147 | 0.0 |
nucleus | Hs | cellular component | 343 | 5.70e-107 |
nucleoplasm | Hs | cellular component | 1147 | 0.0 |
nucleolus | Hs | cellular component | 457 | 1.28e-150 |
cytoplasm | Hs | cellular component | 343 | 5.70e-107 |
Golgi apparatus | Hs | cellular component | 343 | 5.70e-107 |
polar microtubule | Hs | cellular component | 343 | 5.70e-107 |
cytosol | Hs | cellular component | 1147 | 0.0 |
membrane | Hs | cellular component | 343 | 5.70e-107 |
SCF ubiquitin ligase complex | Hs | cellular component | 1147 | 0.0 |
cyclin binding | Hs | molecular function | 343 | 5.70e-107 |
VCB complex | Hs | cellular component | 457 | 1.28e-150 |
POZ domain binding | Hs | molecular function | 343 | 5.70e-107 |
cullin-RING ubiquitin ligase complex | Hs | cellular component | 1147 | 0.0 |
Cul2-RING ubiquitin ligase complex | Hs | cellular component | 457 | 1.28e-150 |
Cul3-RING ubiquitin ligase complex | Hs | cellular component | 343 | 5.70e-107 |
ubiquitin protein ligase binding | Hs | molecular function | 1147 | 0.0 |
sperm flagellum | Hs | cellular component | 343 | 5.70e-107 |
protein homodimerization activity | Hs | molecular function | 343 | 5.70e-107 |
protein heterodimerization activity | Hs | molecular function | 343 | 5.70e-107 |
ubiquitin protein ligase activity | Hs | molecular function | 1147 | 0.0 |
extracellular exosome | Hs | cellular component | 343 | 5.70e-107 |
Parkin-FBXW7-Cul1 ubiquitin ligase complex | Hs | cellular component | 1147 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ubiquitin-dependent protein catabolic process | Pfam | biological process | 3.9E-191 |
cullin-RING ubiquitin ligase complex | ProSitePatterns | cellular component | |
ubiquitin protein ligase binding | Pfam | molecular function | 3.9E-191 |