Gene Card
Best human hits
DAPP1; PLEKHA1; PTPN11
Unique Gene ID
Cirobu.g00008922
Gene Model ID
KH2012:KH.C8.300
Location
KhC8:5956676..5958980
Transcript Models and Sequences
KH2012:KH.C8.300.v1.A.nonSL4-1
KH2012:KH.C8.300.v1.A.SL2-1
KH2012:KH.C8.300.v1.A.SL3-1
KH2012:KH.C8.300.v1.R.ND1-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000023672 |
cien148828
Plate: VES93_K12
n/a
You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see how you can interact with this tree
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Pleckstrin | PANTHER | Pleckstrin |
PH_domain | Pfam | Pleckstrin homology domain |
SH2_dom_sf | Gene3D | SH2 domain superfamily |
PH-like_dom_sf | Gene3D | PH-like domain superfamily |
PH_domain | ProSiteProfiles | Pleckstrin homology domain |
PH_domain | SMART | Pleckstrin homology domain |
SH2_dom_sf | SUPERFAMILY | SH2 domain superfamily |
SH2 | ProSiteProfiles | SH2 domain |
SH2 | Pfam | SH2 domain |
SH2 | SMART | SH2 domain |
SH2 | PRINTS | SH2 domain |
GO Term | Annotation Origin | Type |
---|---|---|
protein binding | Orthology | molecular function |
nucleus | Blast | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Blast | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
protein dephosphorylation | Orthology | biological process |
signal transduction | Orthology | biological process |
positive regulation of signal transduction | Blast | biological process |
membrane | Orthology | cellular component |
dephosphorylation | Blast | biological process |
hydrolase activity | Blast | molecular function |
macromolecular complex | Blast | cellular component |
cell adhesion molecule binding | Blast | molecular function |
extracellular exosome | Blast | cellular component |
anion binding | Orthology | molecular function |
receptor binding | Blast | molecular function |
macromolecular complex binding | Blast | molecular function |
binding | Blast | molecular function |
phosphotransferase activity, alcohol group as acceptor | Blast | molecular function |
cellular biosynthetic process | Blast | biological process |
kinase activity | Blast | molecular function |
protein kinase binding | Blast | molecular function |
cell projection membrane | Blast | cellular component |
cell leading edge | Blast | cellular component |
enzyme binding | Blast | molecular function |
organic substance metabolic process | Blast | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
protein binding | Hs | molecular function |
phospholipid binding | Hs | molecular function |
phosphatidylinositol-3,4,5-trisphosphate binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
protein dephosphorylation | Hs | biological process |
signal transduction | Hs | biological process |
membrane | Hs | cellular component |
PDZ domain binding | Hs | molecular function |
phosphatidylinositol-3,4-bisphosphate binding | Hs | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
phosphoprotein phosphatase activity | Hs | molecular function | 55.5 | 8.66e-09 |
protein tyrosine phosphatase activity | Hs | molecular function | 55.5 | 8.66e-09 |
non-membrane spanning protein tyrosine phosphatase activity | Hs | molecular function | 55.5 | 8.66e-09 |
SH3/SH2 adaptor activity | Hs | molecular function | 55.5 | 8.66e-09 |
insulin receptor binding | Hs | molecular function | 55.5 | 8.66e-09 |
protein binding | Hs | molecular function | 190 | 9.45e-60 |
phospholipid binding | Hs | molecular function | 190 | 9.45e-60 |
phosphatidylinositol-3,4,5-trisphosphate binding | Hs | molecular function | 190 | 9.45e-60 |
nucleus | Hs | cellular component | 60.1 | 2.36e-10 |
nucleoplasm | Hs | cellular component | 60.1 | 2.36e-10 |
cytoplasm | Hs | cellular component | 190 | 9.45e-60 |
mitochondrion | Hs | cellular component | 55.5 | 8.66e-09 |
cytosol | Hs | cellular component | 190 | 9.45e-60 |
plasma membrane | Hs | cellular component | 190 | 9.45e-60 |
lipid binding | Hs | molecular function | 60.1 | 2.36e-10 |
membrane | Hs | cellular component | 190 | 9.45e-60 |
1-phosphatidylinositol-3-kinase activity | Hs | molecular function | 55.5 | 8.66e-09 |
hydrolase activity | Hs | molecular function | 55.5 | 8.66e-09 |
phosphatase activity | Hs | molecular function | 55.5 | 8.66e-09 |
protein domain specific binding | Hs | molecular function | 55.5 | 8.66e-09 |
PDZ domain binding | Hs | molecular function | 190 | 9.45e-60 |
receptor tyrosine kinase binding | Hs | molecular function | 55.5 | 8.66e-09 |
D1 dopamine receptor binding | Hs | molecular function | 55.5 | 8.66e-09 |
ruffle membrane | Hs | cellular component | 60.1 | 2.36e-10 |
macromolecular complex | Hs | cellular component | 55.5 | 8.66e-09 |
phospholipase binding | Hs | molecular function | 55.5 | 8.66e-09 |
phosphatidylinositol-3,4-bisphosphate binding | Hs | molecular function | 190 | 9.45e-60 |
insulin receptor substrate binding | Hs | molecular function | 55.5 | 8.66e-09 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity | Hs | molecular function | 55.5 | 8.66e-09 |
cell adhesion molecule binding | Hs | molecular function | 55.5 | 8.66e-09 |
peptide hormone receptor binding | Hs | molecular function | 55.5 | 8.66e-09 |
extracellular exosome | Hs | cellular component | 60.1 | 2.36e-10 |
protein tyrosine kinase binding | Hs | molecular function | 55.5 | 8.66e-09 |
GO Term | Analysis | Type | e-value |
---|