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Gene Card

Best human hits

SCN1A; SCN2A; SCN3A

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00010010

Gene Model ID

KH2012:KH.C9.462

Location

KhC9:4058555..4086999

Transcript Models and Sequences

  KH2012:KH.C9.462.v3.A.SL1-1
KH2012:KH.C9.462.v4.A.SL2-1

External Database Gene Card

External database links

1 result

Database Gene ID
NCBI Reference Sequence XM_018813178.1
Collections

Gene collection 1 (N. Satoh)

2 results

cilv011p24

Plate: R1CiGC25p20

citb065g10

Plate: R1CiGC46i17

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term Analysis Definition
Na_trans_assoc Pfam Sodium ion transport-associated
Volt_channel_dom_sf Gene3D Voltage-dependent channel domain superfamily
Na_channel_asu PRINTS Voltage gated sodium channel, alpha subunit
GPHH_dom Pfam Voltage-dependent L-type calcium channel, IQ-associated domain
Ion_trans_dom Pfam Ion transport domain

GOSlim

57 results

GO Term Annotation Origin Type
protein binding Orthology molecular function
intracellular Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Orthology cellular component
ion transport Orthology biological process
sodium ion transport Orthology biological process
nervous system development Orthology biological process
membrane Orthology cellular component
integral component of membrane Orthology cellular component
nuclear body Orthology cellular component
axon Orthology cellular component
intrinsic component of plasma membrane Orthology cellular component
neuronal cell body Orthology cellular component
transmembrane transport Orthology biological process
nucleotide binding Orthology molecular function
calmodulin binding Orthology molecular function
ATP binding Orthology molecular function
endoplasmic reticulum Orthology cellular component
sensory perception Orthology biological process
cell surface Orthology cellular component
enzyme binding Orthology molecular function
protein kinase binding Orthology molecular function
cytoplasmic vesicle Orthology cellular component
ubiquitin protein ligase binding Orthology molecular function
cell projection Orthology cellular component
perinuclear region of cytoplasm Orthology cellular component
extracellular exosome Orthology cellular component
macromolecular complex Orthology cellular component
cellular response to stress Orthology biological process
intracellular signal transduction Orthology biological process
apoptotic process Orthology biological process
cell junction Orthology cellular component
nervous system process Orthology biological process
chemical synaptic transmission Orthology biological process
organelle part Orthology cellular component
cytoplasmic part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
plasma membrane part Orthology cellular component
cell projection part Orthology cellular component
cellular process Orthology biological process
sensory perception of mechanical stimulus Orthology biological process
heart development Orthology biological process
membrane raft Orthology cellular component
plasma membrane region Orthology cellular component
defense response Orthology biological process
multicellular organism development Orthology biological process
brain development Orthology biological process
cytoskeletal protein binding Orthology molecular function
metal ion binding Orthology molecular function
response to stress Orthology biological process
positive regulation of cell proliferation Orthology biological process
signaling Orthology biological process
membrane part Orthology cellular component
localization Orthology biological process
cell-cell signaling Orthology biological process

GO (Orthology)

97 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
action potential Hs biological process
voltage-gated sodium channel complex Hs cellular component
ion channel activity Hs molecular function
voltage-gated ion channel activity Hs molecular function
voltage-gated sodium channel activity Hs molecular function
sodium channel activity Hs molecular function
protein binding Hs molecular function
intracellular Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
ion transport Hs biological process
sodium ion transport Hs biological process
nervous system development Hs biological process
adult walking behavior Hs biological process
intrinsic apoptotic signaling pathway in response to osmotic stress Hs biological process
intercalated disc Hs cellular component
membrane Hs cellular component
integral component of membrane Hs cellular component
nuclear body Hs cellular component
neuronal action potential propagation Hs biological process
neuronal action potential Hs biological process
Z disc Hs cellular component
T-tubule Hs cellular component
axon Hs cellular component
intrinsic component of plasma membrane Hs cellular component
node of Ranvier Hs cellular component
paranode region of axon Hs cellular component
ion transmembrane transport Hs biological process
sodium channel complex Hs cellular component
regulation of ion transmembrane transport Hs biological process
sodium ion transmembrane transport Hs biological process
regulation of membrane potential Hs biological process
myelination Hs biological process
neuronal cell body Hs cellular component
axon initial segment Hs cellular component
neuromuscular process controlling posture Hs biological process
detection of mechanical stimulus involved in sensory perception of pain Hs biological process
neuron apoptotic process Hs biological process
transmembrane transport Hs biological process
membrane depolarization during action potential Hs biological process
nucleotide binding Hs molecular function
regulation of heart rate Hs biological process
cardiac ventricle development Hs biological process
calmodulin binding Hs molecular function
ATP binding Hs molecular function
endoplasmic reticulum Hs cellular component
caveola Hs cellular component
muscle contraction Hs biological process
inflammatory response Hs biological process
peripheral nervous system development Hs biological process
sensory perception Hs biological process
response to toxic substance Hs biological process
post-embryonic development Hs biological process
cell surface Hs cellular component
lateral plasma membrane Hs cellular component
fibroblast growth factor binding Hs molecular function
sensory perception of pain Hs biological process
enzyme binding Hs molecular function
protein kinase binding Hs molecular function
protein domain specific binding Hs molecular function
telencephalon development Hs biological process
cerebellum development Hs biological process
ankyrin binding Hs molecular function
sodium ion binding Hs molecular function
cytoplasmic vesicle Hs cellular component
ubiquitin protein ligase binding Hs molecular function
sarcolemma Hs cellular component
response to drug Hs biological process
cell projection Hs cellular component
C-fiber Hs cellular component
ion channel binding Hs molecular function
positive regulation of action potential Hs biological process
behavioral response to pain Hs biological process
perinuclear region of cytoplasm Hs cellular component
positive regulation of epithelial cell proliferation Hs biological process
nitric-oxide synthase binding Hs molecular function
membrane depolarization Hs biological process
regulation of sensory perception of pain Hs biological process
sodium ion homeostasis Hs biological process
regulation of cardiac muscle contraction Hs biological process
cardiac muscle contraction Hs biological process
regulation of ventricular cardiac muscle cell membrane repolarization Hs biological process
cardiac conduction Hs biological process
extracellular exosome Hs cellular component
cellular response to calcium ion Hs biological process
clathrin complex Hs cellular component
regulation of cardiac muscle cell contraction Hs biological process
voltage-gated sodium channel activity involved in cardiac muscle cell action potential Hs molecular function
voltage-gated sodium channel activity involved in AV node cell action potential Hs molecular function
voltage-gated sodium channel activity involved in bundle of His cell action potential Hs molecular function
voltage-gated sodium channel activity involved in Purkinje myocyte action potential Hs molecular function
voltage-gated sodium channel activity involved in SA node cell action potential Hs molecular function
regulation of heart rate by cardiac conduction Hs biological process
scaffold protein binding Hs molecular function
glial cell projection Hs cellular component

GO (Blast)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
voltage-gated sodium channel complex Hs cellular component 1880 0.0
ion channel activity Hs molecular function 1880 0.0
voltage-gated ion channel activity Hs molecular function 1880 0.0
voltage-gated sodium channel activity Hs molecular function 1880 0.0
sodium channel activity Hs molecular function 1880 0.0
protein binding Hs molecular function 1880 0.0
intracellular Hs cellular component 1880 0.0
nucleoplasm Hs cellular component 1871 0.0
cytoplasm Hs cellular component 1844 0.0
plasma membrane Hs cellular component 1880 0.0
integral component of plasma membrane Hs cellular component 1880 0.0
intercalated disc Hs cellular component 1880 0.0
membrane Hs cellular component 1880 0.0
integral component of membrane Hs cellular component 1880 0.0
nuclear body Hs cellular component 1871 0.0
Z disc Hs cellular component 1871 0.0
T-tubule Hs cellular component 1880 0.0
axon Hs cellular component 1880 0.0
intrinsic component of plasma membrane Hs cellular component 1880 0.0
node of Ranvier Hs cellular component 1880 0.0
paranode region of axon Hs cellular component 1880 0.0
sodium channel complex Hs cellular component 1880 0.0
neuronal cell body Hs cellular component 1871 0.0
axon initial segment Hs cellular component 1871 0.0

GO (InterProScan)

7 results

GO Term Analysis Type e-value
voltage-gated sodium channel complex Pfam cellular component 5.8E-24
ion channel activity Pfam molecular function 1.6E-79
voltage-gated sodium channel activity Pfam molecular function 5.8E-24
ion transport Pfam biological process 1.6E-79
sodium ion transport Pfam biological process 5.8E-24
membrane Pfam cellular component 1.6E-79
transmembrane transport Pfam biological process 1.6E-79

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