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Gene Card

Best human hits

DES; GFAP; VIM

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00010366

Gene Model ID

KH2012:KH.C9.785

Location

KhC9:401641..410292

Transcript Models and Sequences

  KH2012:KH.C9.785.v1.A.ND2-1
KH2012:KH.C9.785.v2.A.SL1-1

External Database Gene Card

External database links

3 results

Database Gene ID
ENSEMBL ENSCING00000006851
NCBI Reference Sequence XM_002119077.4
NCBI Reference Sequence XM_004226379.2
Collections

Gateway full ORF

2 results

cima888670

Plate: VES70_P06

cima873913

Plate: VES67_O07

Gene collection 1 (N. Satoh)

2 results

cilv006b02

Plate: R1CiGC25k20

cilv078j22

Plate: R1CiGC44f23

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term Analysis Definition
Intermediate_filament_CS ProSitePatterns Intermediate filament protein, conserved site
IF SMART Intermediate filament protein
Keratin_I PRINTS Keratin, type I
IF PANTHER Intermediate filament protein
IF Pfam Intermediate filament protein

GOSlim

82 results

GO Term Annotation Origin Type
integrin binding Orthology molecular function
structural molecule activity Orthology molecular function
protein binding Orthology molecular function
intracellular Orthology cellular component
nucleus Orthology cellular component
cytoplasm Orthology cellular component
lysosome Orthology cellular component
peroxisome Orthology cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
plasma membrane Orthology cellular component
focal adhesion Orthology cellular component
protein C-terminus binding Orthology molecular function
cytoskeletal protein binding Orthology molecular function
response to wounding Orthology biological process
positive regulation of gene expression Orthology biological process
membrane Orthology cellular component
cytokine-mediated signaling pathway Orthology biological process
kinase binding Orthology molecular function
extracellular matrix organization Orthology biological process
cell leading edge Orthology cellular component
identical protein binding Orthology molecular function
cell projection Orthology cellular component
neuron projection Orthology cellular component
myelin sheath Orthology cellular component
cell body Orthology cellular component
axon development Orthology biological process
extracellular exosome Orthology cellular component
extracellular space Orthology cellular component
nucleoplasm Orthology cellular component
multicellular organism development Orthology biological process
nervous system development Orthology biological process
microtubule binding Orthology molecular function
response to organic substance Orthology biological process
cell differentiation Orthology biological process
axon Orthology cellular component
nuclear membrane Orthology cellular component
locomotion Orthology biological process
protein heterodimerization activity Orthology molecular function
neuron projection morphogenesis Orthology biological process
regulation of molecular function Orthology biological process
RNA binding Orthology molecular function
organelle organization Orthology biological process
macromolecular complex Orthology cellular component
cytoskeletal part Orthology cellular component
cytoplasmic part Orthology cellular component
cell junction Orthology cellular component
adherens junction Orthology cellular component
neuron projection development Orthology biological process
cell development Orthology biological process
neurogenesis Orthology biological process
central nervous system development Orthology biological process
organelle part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
cellular response to stress Orthology biological process
synapse Orthology cellular component
mRNA catabolic process Orthology biological process
cytoplasmic vesicle Orthology cellular component
generation of neurons Orthology biological process
positive regulation of cell proliferation Orthology biological process
chemical synaptic transmission Orthology biological process
cell surface receptor signaling pathway Orthology biological process
innate immune response Orthology biological process
plasma membrane region Orthology cellular component
membrane part Orthology cellular component
lysosomal membrane Orthology cellular component
macromolecular complex binding Orthology molecular function
intracellular signal transduction Orthology biological process
protein phosphorylation Orthology biological process
microtubule-based process Orthology biological process
enzyme binding Orthology molecular function
molecular function regulator Orthology molecular function
cell projection part Orthology cellular component
microtubule-based movement Orthology biological process
intracellular transport Orthology biological process
animal organ development Orthology biological process
brain development Orthology biological process
negative regulation of apoptotic process Orthology biological process
axonogenesis Orthology biological process
nervous system process Orthology biological process
intracellular part Orthology cellular component
neuron part Orthology cellular component

GO (Orthology)

103 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
double-stranded RNA binding Hs molecular function
integrin binding Hs molecular function
structural molecule activity Hs molecular function
structural constituent of cytoskeleton Hs molecular function
structural constituent of eye lens Hs molecular function
protein binding Hs molecular function
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
lysosome Hs cellular component
peroxisome Hs cellular component
cytosol Hs cellular component
polysome Hs cellular component
cytoskeleton Hs cellular component
intermediate filament Hs cellular component
neurofilament Hs cellular component
plasma membrane Hs cellular component
cell-cell junction Hs cellular component
fascia adherens Hs cellular component
focal adhesion Hs cellular component
muscle contraction Hs biological process
cytoskeleton organization Hs biological process
regulation of heart contraction Hs biological process
protein C-terminus binding Hs molecular function
cytoskeletal protein binding Hs molecular function
response to wounding Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of neuron projection development Hs biological process
astrocyte development Hs biological process
intercalated disc Hs cellular component
membrane Hs cellular component
viral process Hs biological process
cytokine-mediated signaling pathway Hs biological process
kinase binding Hs molecular function
protein domain specific binding Hs molecular function
Z disc Hs cellular component
extracellular matrix organization Hs biological process
intracellular ribonucleoprotein complex Hs cellular component
neuron projection regeneration Hs biological process
cell leading edge Hs cellular component
neuromuscular junction Hs cellular component
sarcolemma Hs cellular component
identical protein binding Hs molecular function
cell projection Hs cellular component
neuron projection Hs cellular component
myelin sheath Hs cellular component
contractile fiber Hs cellular component
regulation of mRNA stability Hs biological process
cell body Hs cellular component
intermediate filament organization Hs biological process
intermediate filament cytoskeleton Hs cellular component
phagocytic vesicle Hs cellular component
positive regulation of translation Hs biological process
positive regulation of glial cell proliferation Hs biological process
long-term synaptic potentiation Hs biological process
SMAD protein signal transduction Hs biological process
axon development Hs biological process
extracellular exosome Hs cellular component
cellular response to interferon-gamma Hs biological process
scaffold protein binding Hs molecular function
glial cell projection Hs cellular component
astrocyte projection Hs cellular component
astrocyte end-foot Hs cellular component
cardiac myofibril Hs cellular component
cytoplasmic side of lysosomal membrane Hs cellular component
keratin filament binding Hs molecular function
MAPK cascade Hs biological process
microtubule cytoskeleton organization Hs biological process
Ras guanyl-nucleotide exchange factor activity Hs molecular function
extracellular space Hs cellular component
nucleoplasm Hs cellular component
multicellular organism development Hs biological process
nervous system development Hs biological process
microtubule binding Hs molecular function
anterograde axonal transport Hs biological process
retrograde axonal transport Hs biological process
response to toxic substance Hs biological process
response to organic substance Hs biological process
axonal transport of mitochondrion Hs biological process
spinal cord development Hs biological process
cerebral cortex development Hs biological process
cell differentiation Hs biological process
axon Hs cellular component
growth cone Hs cellular component
protein binding, bridging Hs molecular function
nuclear membrane Hs cellular component
TSC1-TSC2 complex Hs cellular component
cytoplasmic ribonucleoprotein granule Hs cellular component
locomotion Hs biological process
phospholipase binding Hs molecular function
response to peptide hormone Hs biological process
negative regulation of neuron apoptotic process Hs biological process
type III intermediate filament Hs cellular component
intermediate filament cytoskeleton organization Hs biological process
protein heterodimerization activity Hs molecular function
neuron projection morphogenesis Hs biological process
positive regulation of axonogenesis Hs biological process
neuromuscular process controlling balance Hs biological process
protein polymerization Hs biological process
neurofilament cytoskeleton organization Hs biological process
regulation of molecular function Hs biological process
neurofibrillary tangle Hs cellular component
axon cytoplasm Hs cellular component

GO (Blast)

47 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
double-stranded RNA binding Hs molecular function 327 1.75e-107
integrin binding Hs molecular function 293 9.25e-95
structural molecule activity Hs molecular function 327 1.75e-107
structural constituent of cytoskeleton Hs molecular function 327 1.75e-107
structural constituent of eye lens Hs molecular function 327 1.75e-107
protein binding Hs molecular function 327 1.75e-107
intracellular Hs cellular component 293 9.25e-95
nucleus Hs cellular component 278 1.69e-88
cytoplasm Hs cellular component 327 1.75e-107
lysosome Hs cellular component 293 9.25e-95
peroxisome Hs cellular component 327 1.75e-107
cytosol Hs cellular component 327 1.75e-107
polysome Hs cellular component 327 1.75e-107
cytoskeleton Hs cellular component 327 1.75e-107
intermediate filament Hs cellular component 327 1.75e-107
neurofilament Hs cellular component 293 9.25e-95
plasma membrane Hs cellular component 327 1.75e-107
cell-cell junction Hs cellular component 278 1.69e-88
fascia adherens Hs cellular component 278 1.69e-88
focal adhesion Hs cellular component 327 1.75e-107
protein C-terminus binding Hs molecular function 327 1.75e-107
cytoskeletal protein binding Hs molecular function 278 1.69e-88
intercalated disc Hs cellular component 278 1.69e-88
membrane Hs cellular component 293 9.25e-95
kinase binding Hs molecular function 293 9.25e-95
protein domain specific binding Hs molecular function 327 1.75e-107
Z disc Hs cellular component 278 1.69e-88
intracellular ribonucleoprotein complex Hs cellular component 327 1.75e-107
cell leading edge Hs cellular component 327 1.75e-107
neuromuscular junction Hs cellular component 278 1.69e-88
sarcolemma Hs cellular component 278 1.69e-88
identical protein binding Hs molecular function 327 1.75e-107
cell projection Hs cellular component 327 1.75e-107
neuron projection Hs cellular component 327 1.75e-107
myelin sheath Hs cellular component 293 9.25e-95
contractile fiber Hs cellular component 278 1.69e-88
cell body Hs cellular component 293 9.25e-95
intermediate filament cytoskeleton Hs cellular component 293 9.25e-95
phagocytic vesicle Hs cellular component 327 1.75e-107
extracellular exosome Hs cellular component 327 1.75e-107
scaffold protein binding Hs molecular function 327 1.75e-107
glial cell projection Hs cellular component 293 9.25e-95
astrocyte projection Hs cellular component 293 9.25e-95
astrocyte end-foot Hs cellular component 293 9.25e-95
cardiac myofibril Hs cellular component 278 1.69e-88
cytoplasmic side of lysosomal membrane Hs cellular component 293 9.25e-95
keratin filament binding Hs molecular function 327 1.75e-107

GO (InterProScan)

2 results

GO Term Analysis Type e-value
structural molecule activity PANTHER molecular function 9.8E-151
intermediate filament PANTHER cellular component 9.8E-151

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