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GENE CARD

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Gene Card

Best human hits

ITGA11; ITGA2; ITGAM

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00010373

Gene Model ID

KH2012:KH.C9.791

Location

KhC9:3381536..3396594

Transcript Models and Sequences

  KH2012:KH.C9.791.v1.A.SL1-1
KH2012:KH.C9.791.v1.A.SL2-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000019119
NCBI Reference Sequence XM_002122112.2
Collections

Gene collection 1 (N. Satoh)

1 result

cilv037f03

Plate: R1CiGC28e23

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
Int_alpha_beta-p ProSiteProfiles Integrin alpha beta-propellor
vWFA_dom_sf SUPERFAMILY von Willebrand factor A-like domain superfamily
VWF_A Pfam von Willebrand factor, type A
Integrin_alpha PRINTS Integrin alpha chain
Integrin_alpha_N Gene3D Integrin alpha, N-terminal
Integrin_dom_sf SUPERFAMILY Integrin domain superfamily
FG-GAP Pfam FG-GAP repeat
Int_alpha_beta-p SMART Integrin alpha beta-propellor
VWF_A SMART von Willebrand factor, type A
VWF_A ProSiteProfiles von Willebrand factor, type A
vWFA_dom_sf Gene3D von Willebrand factor A-like domain superfamily
Integrin_alpha-2 Pfam Integrin alpha-2

GOSlim

82 results

GO Term Annotation Origin Type
response to hypoxia Orthology biological process
immune system process Orthology biological process
integrin binding Orthology molecular function
protein binding Orthology molecular function
extracellular space Orthology cellular component
nucleus Orthology cellular component
plasma membrane Orthology cellular component
focal adhesion Orthology cellular component
cell adhesion Orthology biological process
blood coagulation Orthology biological process
cell proliferation Orthology biological process
cell surface Orthology cellular component
membrane Orthology cellular component
integral component of membrane Orthology cellular component
cytokine-mediated signaling pathway Orthology biological process
extracellular matrix organization Orthology biological process
axon Orthology cellular component
wound healing Orthology biological process
cell projection Orthology cellular component
macromolecular complex binding Orthology molecular function
innate immune response Orthology biological process
membrane raft Orthology cellular component
establishment of protein localization Orthology biological process
metal ion binding Orthology molecular function
protein heterodimerization activity Orthology molecular function
perinuclear region of cytoplasm Orthology cellular component
extracellular exosome Orthology cellular component
receptor binding Orthology molecular function
immune response Orthology biological process
signal transduction Orthology biological process
negative regulation of cell proliferation Orthology biological process
neuron projection Orthology cellular component
neuron projection morphogenesis Orthology biological process
cell adhesion molecule binding Orthology molecular function
binding Orthology molecular function
cell differentiation Orthology biological process
cellular process Orthology biological process
defense response Orthology biological process
membrane organization Orthology biological process
organelle organization Orthology biological process
cell migration Orthology biological process
cell surface receptor signaling pathway Orthology biological process
animal organ development Orthology biological process
integral component of plasma membrane Orthology cellular component
macromolecular complex Orthology cellular component
anatomical structure morphogenesis Orthology biological process
plasma membrane part Orthology cellular component
response to organic substance Orthology biological process
cell projection organization Orthology biological process
whole membrane Orthology cellular component
intracellular organelle part Orthology cellular component
cytoplasmic vesicle Orthology cellular component
endomembrane system Orthology cellular component
bounding membrane of organelle Orthology cellular component
transmembrane signaling receptor activity Orthology molecular function
DNA binding Orthology molecular function
anion binding Orthology molecular function
carbohydrate derivative binding Orthology molecular function
cell projection part Orthology cellular component
synapse part Orthology cellular component
plasma membrane region Orthology cellular component
cell part Orthology cellular component
positive regulation of gene expression Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
multicellular organism development Orthology biological process
chemotaxis Orthology biological process
sensory perception of mechanical stimulus Orthology biological process
response to lipid Orthology biological process
cellular response to organic substance Orthology biological process
protein targeting to membrane Orthology biological process
positive regulation of cell death Orthology biological process
positive regulation of catalytic activity Orthology biological process
intracellular signal transduction Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
positive regulation of signal transduction Orthology biological process
enzyme binding Orthology molecular function
protein dephosphorylation Orthology biological process
positive regulation of hydrolase activity Orthology biological process
negative regulation of signal transduction Orthology biological process
protein localization to membrane Orthology biological process
neuronal cell body Orthology cellular component
positive regulation of apoptotic process Orthology biological process

GO (Orthology)

112 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
amyloid-beta binding Hs molecular function
virus receptor activity Hs molecular function
osteoblast differentiation Hs biological process
response to hypoxia Hs biological process
microglial cell activation Hs biological process
complement component C3b binding Hs molecular function
immune system process Hs biological process
integrin binding Hs molecular function
protein binding Hs molecular function
collagen binding Hs molecular function
extracellular space Hs cellular component
nucleus Hs cellular component
plasma membrane Hs cellular component
focal adhesion Hs cellular component
phagocytosis, engulfment Hs biological process
substrate-dependent cell migration Hs biological process
cell adhesion Hs biological process
cell-matrix adhesion Hs biological process
integrin-mediated signaling pathway Hs biological process
muscle organ development Hs biological process
blood coagulation Hs biological process
cell proliferation Hs biological process
integrin complex Hs cellular component
animal organ morphogenesis Hs biological process
external side of plasma membrane Hs cellular component
cell surface Hs cellular component
response to organic cyclic compound Hs biological process
membrane Hs cellular component
integral component of membrane Hs cellular component
viral process Hs biological process
cytokine-mediated signaling pathway Hs biological process
extracellular matrix organization Hs biological process
axon Hs cellular component
heat shock protein binding Hs molecular function
positive regulation of cell projection organization Hs biological process
cell-substrate adhesion Hs biological process
cell adhesion mediated by integrin Hs biological process
toll-like receptor 4 signaling pathway Hs biological process
integrin alpha2-beta1 complex Hs cellular component
integrin alpha11-beta1 complex Hs cellular component
integrin alphaM-beta2 complex Hs cellular component
specific granule membrane Hs cellular component
collagen receptor activity Hs molecular function
wound healing Hs biological process
response to drug Hs biological process
cell projection Hs cellular component
laminin binding Hs molecular function
positive regulation of DNA binding Hs biological process
heparan sulfate proteoglycan binding Hs molecular function
skin morphogenesis Hs biological process
axon terminus Hs cellular component
plasma membrane raft Hs cellular component
macromolecular complex binding Hs molecular function
innate immune response Hs biological process
membrane raft Hs cellular component
basal part of cell Hs cellular component
establishment of protein localization Hs biological process
positive regulation of translation Hs biological process
positive regulation of cell adhesion Hs biological process
positive regulation of smooth muscle contraction Hs biological process
viral entry into host cell Hs biological process
metal ion binding Hs molecular function
protein heterodimerization activity Hs molecular function
focal adhesion assembly Hs biological process
mesodermal cell differentiation Hs biological process
perinuclear region of cytoplasm Hs cellular component
positive regulation of inflammatory response Hs biological process
leukocyte migration Hs biological process
positive regulation of positive chemotaxis Hs biological process
detection of mechanical stimulus involved in sensory perception of pain Hs biological process
positive regulation of phagocytosis, engulfment Hs biological process
extracellular exosome Hs cellular component
hepatocyte differentiation Hs biological process
tertiary granule membrane Hs cellular component
cellular response to mechanical stimulus Hs biological process
cellular response to estradiol stimulus Hs biological process
cellular response to organic cyclic compound Hs biological process
positive regulation of protein targeting to membrane Hs biological process
collagen binding involved in cell-matrix adhesion Hs molecular function
positive regulation of neuron death Hs biological process
activation of MAPK activity Hs biological process
acrosomal vesicle Hs cellular component
receptor activity Hs molecular function
receptor binding Hs molecular function
phagocytosis Hs biological process
muscle contraction Hs biological process
inflammatory response Hs biological process
immune response Hs biological process
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Hs biological process
signal transduction Hs biological process
negative regulation of cell proliferation Hs biological process
protein phosphatase binding Hs molecular function
ICAM-3 receptor activity Hs molecular function
neutrophil chemotaxis Hs biological process
secretory granule membrane Hs cellular component
positive regulation of phosphoprotein phosphatase activity Hs biological process
integrin alpha1-beta1 complex Hs cellular component
integrin alpha10-beta1 complex Hs cellular component
integrin alphaL-beta2 complex Hs cellular component
negative regulation of epidermal growth factor receptor signaling pathway Hs biological process
vasodilation Hs biological process
neuron projection Hs cellular component
receptor clustering Hs biological process
perikaryon Hs cellular component
positive regulation of neuron apoptotic process Hs biological process
neuron projection morphogenesis Hs biological process
regulation of immune response Hs biological process
cell adhesion molecule binding Hs molecular function
defense response to virus Hs biological process
cell chemotaxis Hs biological process
cell-cell adhesion Hs biological process
ficolin-1-rich granule membrane Hs cellular component

GO (Blast)

36 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
amyloid-beta binding Hs molecular function 206 7.49e-54
virus receptor activity Hs molecular function 206 7.49e-54
complement component C3b binding Hs molecular function 199 6.58e-52
integrin binding Hs molecular function 206 7.49e-54
protein binding Hs molecular function 206 7.49e-54
collagen binding Hs molecular function 206 7.49e-54
extracellular space Hs cellular component 199 6.58e-52
nucleus Hs cellular component 206 7.49e-54
plasma membrane Hs cellular component 206 7.49e-54
focal adhesion Hs cellular component 206 7.49e-54
integrin complex Hs cellular component 206 7.49e-54
external side of plasma membrane Hs cellular component 206 7.49e-54
cell surface Hs cellular component 206 7.49e-54
membrane Hs cellular component 206 7.49e-54
integral component of membrane Hs cellular component 206 7.49e-54
axon Hs cellular component 206 7.49e-54
heat shock protein binding Hs molecular function 199 6.58e-52
integrin alpha2-beta1 complex Hs cellular component 206 7.49e-54
integrin alpha11-beta1 complex Hs cellular component 202 1.38e-52
integrin alphaM-beta2 complex Hs cellular component 199 6.58e-52
specific granule membrane Hs cellular component 199 6.58e-52
collagen receptor activity Hs molecular function 206 7.49e-54
cell projection Hs cellular component 206 7.49e-54
laminin binding Hs molecular function 206 7.49e-54
heparan sulfate proteoglycan binding Hs molecular function 206 7.49e-54
axon terminus Hs cellular component 206 7.49e-54
plasma membrane raft Hs cellular component 199 6.58e-52
macromolecular complex binding Hs molecular function 206 7.49e-54
membrane raft Hs cellular component 199 6.58e-52
basal part of cell Hs cellular component 206 7.49e-54
metal ion binding Hs molecular function 206 7.49e-54
protein heterodimerization activity Hs molecular function 206 7.49e-54
perinuclear region of cytoplasm Hs cellular component 206 7.49e-54
extracellular exosome Hs cellular component 199 6.58e-52
tertiary granule membrane Hs cellular component 199 6.58e-52
collagen binding involved in cell-matrix adhesion Hs molecular function 206 7.49e-54

GO (InterProScan)

2 results

GO Term Analysis Type e-value
cell adhesion PRINTS biological process 1.9E-39
integrin complex PRINTS cellular component 1.9E-39

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