Gene Card
Best human hits
ITGA11; ITGA2; ITGAM
Unique Gene ID
Cirobu.g00010373
Gene Model ID
KH2012:KH.C9.791
Location
KhC9:3381536..3396594
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000019119 |
NCBI Reference Sequence | XM_002122112.2 |
cilv037f03
Plate: R1CiGC28e23
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Int_alpha_beta-p | ProSiteProfiles | Integrin alpha beta-propellor |
vWFA_dom_sf | SUPERFAMILY | von Willebrand factor A-like domain superfamily |
VWF_A | Pfam | von Willebrand factor, type A |
Integrin_alpha | PRINTS | Integrin alpha chain |
Integrin_alpha_N | Gene3D | Integrin alpha, N-terminal |
Integrin_dom_sf | SUPERFAMILY | Integrin domain superfamily |
FG-GAP | Pfam | FG-GAP repeat |
Int_alpha_beta-p | SMART | Integrin alpha beta-propellor |
VWF_A | SMART | von Willebrand factor, type A |
VWF_A | ProSiteProfiles | von Willebrand factor, type A |
vWFA_dom_sf | Gene3D | von Willebrand factor A-like domain superfamily |
Integrin_alpha-2 | Pfam | Integrin alpha-2 |
GO Term | Annotation Origin | Type |
---|---|---|
response to hypoxia | Orthology | biological process |
immune system process | Orthology | biological process |
integrin binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
extracellular space | Orthology | cellular component |
nucleus | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
focal adhesion | Orthology | cellular component |
cell adhesion | Orthology | biological process |
blood coagulation | Orthology | biological process |
cell proliferation | Orthology | biological process |
cell surface | Orthology | cellular component |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
cytokine-mediated signaling pathway | Orthology | biological process |
extracellular matrix organization | Orthology | biological process |
axon | Orthology | cellular component |
wound healing | Orthology | biological process |
cell projection | Orthology | cellular component |
macromolecular complex binding | Orthology | molecular function |
innate immune response | Orthology | biological process |
membrane raft | Orthology | cellular component |
establishment of protein localization | Orthology | biological process |
metal ion binding | Orthology | molecular function |
protein heterodimerization activity | Orthology | molecular function |
perinuclear region of cytoplasm | Orthology | cellular component |
extracellular exosome | Orthology | cellular component |
receptor binding | Orthology | molecular function |
immune response | Orthology | biological process |
signal transduction | Orthology | biological process |
negative regulation of cell proliferation | Orthology | biological process |
neuron projection | Orthology | cellular component |
neuron projection morphogenesis | Orthology | biological process |
cell adhesion molecule binding | Orthology | molecular function |
binding | Orthology | molecular function |
cell differentiation | Orthology | biological process |
cellular process | Orthology | biological process |
defense response | Orthology | biological process |
membrane organization | Orthology | biological process |
organelle organization | Orthology | biological process |
cell migration | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
animal organ development | Orthology | biological process |
integral component of plasma membrane | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
anatomical structure morphogenesis | Orthology | biological process |
plasma membrane part | Orthology | cellular component |
response to organic substance | Orthology | biological process |
cell projection organization | Orthology | biological process |
whole membrane | Orthology | cellular component |
intracellular organelle part | Orthology | cellular component |
cytoplasmic vesicle | Orthology | cellular component |
endomembrane system | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
transmembrane signaling receptor activity | Orthology | molecular function |
DNA binding | Orthology | molecular function |
anion binding | Orthology | molecular function |
carbohydrate derivative binding | Orthology | molecular function |
cell projection part | Orthology | cellular component |
synapse part | Orthology | cellular component |
plasma membrane region | Orthology | cellular component |
cell part | Orthology | cellular component |
positive regulation of gene expression | Orthology | biological process |
anatomical structure formation involved in morphogenesis | Orthology | biological process |
multicellular organism development | Orthology | biological process |
chemotaxis | Orthology | biological process |
sensory perception of mechanical stimulus | Orthology | biological process |
response to lipid | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
protein targeting to membrane | Orthology | biological process |
positive regulation of cell death | Orthology | biological process |
positive regulation of catalytic activity | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
protein serine/threonine kinase activity | Orthology | molecular function |
positive regulation of signal transduction | Orthology | biological process |
enzyme binding | Orthology | molecular function |
protein dephosphorylation | Orthology | biological process |
positive regulation of hydrolase activity | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
protein localization to membrane | Orthology | biological process |
neuronal cell body | Orthology | cellular component |
positive regulation of apoptotic process | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
amyloid-beta binding | Hs | molecular function | 206 | 7.49e-54 |
virus receptor activity | Hs | molecular function | 206 | 7.49e-54 |
complement component C3b binding | Hs | molecular function | 199 | 6.58e-52 |
integrin binding | Hs | molecular function | 206 | 7.49e-54 |
protein binding | Hs | molecular function | 206 | 7.49e-54 |
collagen binding | Hs | molecular function | 206 | 7.49e-54 |
extracellular space | Hs | cellular component | 199 | 6.58e-52 |
nucleus | Hs | cellular component | 206 | 7.49e-54 |
plasma membrane | Hs | cellular component | 206 | 7.49e-54 |
focal adhesion | Hs | cellular component | 206 | 7.49e-54 |
integrin complex | Hs | cellular component | 206 | 7.49e-54 |
external side of plasma membrane | Hs | cellular component | 206 | 7.49e-54 |
cell surface | Hs | cellular component | 206 | 7.49e-54 |
membrane | Hs | cellular component | 206 | 7.49e-54 |
integral component of membrane | Hs | cellular component | 206 | 7.49e-54 |
axon | Hs | cellular component | 206 | 7.49e-54 |
heat shock protein binding | Hs | molecular function | 199 | 6.58e-52 |
integrin alpha2-beta1 complex | Hs | cellular component | 206 | 7.49e-54 |
integrin alpha11-beta1 complex | Hs | cellular component | 202 | 1.38e-52 |
integrin alphaM-beta2 complex | Hs | cellular component | 199 | 6.58e-52 |
specific granule membrane | Hs | cellular component | 199 | 6.58e-52 |
collagen receptor activity | Hs | molecular function | 206 | 7.49e-54 |
cell projection | Hs | cellular component | 206 | 7.49e-54 |
laminin binding | Hs | molecular function | 206 | 7.49e-54 |
heparan sulfate proteoglycan binding | Hs | molecular function | 206 | 7.49e-54 |
axon terminus | Hs | cellular component | 206 | 7.49e-54 |
plasma membrane raft | Hs | cellular component | 199 | 6.58e-52 |
macromolecular complex binding | Hs | molecular function | 206 | 7.49e-54 |
membrane raft | Hs | cellular component | 199 | 6.58e-52 |
basal part of cell | Hs | cellular component | 206 | 7.49e-54 |
metal ion binding | Hs | molecular function | 206 | 7.49e-54 |
protein heterodimerization activity | Hs | molecular function | 206 | 7.49e-54 |
perinuclear region of cytoplasm | Hs | cellular component | 206 | 7.49e-54 |
extracellular exosome | Hs | cellular component | 199 | 6.58e-52 |
tertiary granule membrane | Hs | cellular component | 199 | 6.58e-52 |
collagen binding involved in cell-matrix adhesion | Hs | molecular function | 206 | 7.49e-54 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
cell adhesion | PRINTS | biological process | 1.9E-39 |
integrin complex | PRINTS | cellular component | 1.9E-39 |