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GENE CARD

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Gene Card

Best human hits

FURIN; PCSK1; PCSK2

Unique Gene ID

Cirobu.g00010959

Gene Model ID

KH2012:KH.L128.2

Location

KhL128:212528..231064

Transcript Models and Sequences

  KH2012:KH.L128.2.v1.A.SL1-1

External Database Gene Card
Collections

Gene collection 1 (N. Satoh)

1 result

cilv026a23

Plate: R1CiGC27a18

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Genomicus Synteny Browser

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Gene Phylogeny

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Gene Annotations

InterPro

14 results

IPR Term Analysis Definition
Peptidase_S8/S53_dom_sf Gene3D Peptidase S8/S53 domain superfamily
Kexin/furin CDD Kexin/furin catalytic domain
Peptidase_S8/S53_dom Pfam Peptidase S8/S53 domain
Peptidase_S8_His-AS ProSitePatterns Peptidase S8, subtilisin, His-active site
Peptidase_S8_subtilisin-rel PRINTS Peptidase S8, subtilisin-related
Peptidase_S8/S53_dom_sf SUPERFAMILY Peptidase S8/S53 domain superfamily
Peptidase_S8_Ser-AS ProSitePatterns Peptidase S8, subtilisin, Ser-active site
P_dom Pfam P domain
Galactose-bd-like_sf Gene3D Galactose-binding-like domain superfamily
S8_pro-domain Pfam Peptidase S8, pro-domain
P_dom ProSiteProfiles P domain
S8_pro-domain_sf Gene3D Peptidase S8, pro-domain superfamily
Peptidase_S8_Asp-AS ProSitePatterns Peptidase S8, subtilisin, Asp-active site
Galactose-bd-like_sf SUPERFAMILY Galactose-binding-like domain superfamily

GOSlim

37 results

GO Term Annotation Origin Type
Golgi membrane Blast cellular component
endopeptidase activity Orthology molecular function
serine-type endopeptidase activity Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
nucleus Orthology cellular component
endosome Blast cellular component
endoplasmic reticulum Blast cellular component
Golgi apparatus Blast cellular component
plasma membrane Blast cellular component
proteolysis Orthology biological process
nervous system development Orthology biological process
peptidase activity Orthology molecular function
serine-type peptidase activity Orthology molecular function
cell surface Blast cellular component
membrane Orthology cellular component
integral component of membrane Blast cellular component
hydrolase activity Orthology molecular function
cytoplasmic vesicle Orthology cellular component
identical protein binding Blast molecular function
neuronal cell body Orthology cellular component
intracellular membrane-bounded organelle Orthology cellular component
membrane raft Blast cellular component
metal ion binding Blast molecular function
extracellular exosome Blast cellular component
gene expression Orthology biological process
peptide metabolic process Orthology biological process
endomembrane system Orthology cellular component
intracellular organelle part Orthology cellular component
intracellular organelle lumen Orthology cellular component
enzyme binding Blast molecular function
enzyme regulator activity Blast molecular function
Golgi apparatus part Blast cellular component
whole membrane Blast cellular component
bounding membrane of organelle Blast cellular component
binding Blast molecular function

GO (Orthology)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
endopeptidase activity Hs molecular function
serine-type endopeptidase activity Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
extracellular space Hs cellular component
nucleus Hs cellular component
proteolysis Hs biological process
nervous system development Hs biological process
peptidase activity Hs molecular function
serine-type peptidase activity Hs molecular function
membrane Hs cellular component
protein processing Hs biological process
peptide hormone processing Hs biological process
protein autoprocessing Hs biological process
hydrolase activity Hs molecular function
insulin processing Hs biological process
transport vesicle Hs cellular component
secretory granule Hs cellular component
dendrite Hs cellular component
cytoplasmic vesicle Hs cellular component
secretory granule lumen Hs cellular component
neuronal cell body Hs cellular component
perikaryon Hs cellular component
intracellular membrane-bounded organelle Hs cellular component

GO (Blast)

37 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
Golgi membrane Hs cellular component 513 4.11e-173
protease binding Hs molecular function 513 4.11e-173
endopeptidase activity Hs molecular function 826 0.0
serine-type endopeptidase activity Hs molecular function 826 0.0
serine-type endopeptidase inhibitor activity Hs molecular function 513 4.11e-173
protein binding Hs molecular function 826 0.0
extracellular region Hs cellular component 826 0.0
extracellular space Hs cellular component 826 0.0
nucleus Hs cellular component 826 0.0
endosome Hs cellular component 513 4.11e-173
endoplasmic reticulum Hs cellular component 513 4.11e-173
Golgi apparatus Hs cellular component 513 4.11e-173
Golgi lumen Hs cellular component 513 4.11e-173
trans-Golgi network Hs cellular component 513 4.11e-173
plasma membrane Hs cellular component 513 4.11e-173
peptidase activity Hs molecular function 826 0.0
serine-type peptidase activity Hs molecular function 826 0.0
cell surface Hs cellular component 513 4.11e-173
endosome membrane Hs cellular component 513 4.11e-173
membrane Hs cellular component 826 0.0
integral component of membrane Hs cellular component 513 4.11e-173
hydrolase activity Hs molecular function 826 0.0
transport vesicle Hs cellular component 826 0.0
trans-Golgi network transport vesicle Hs cellular component 513 4.11e-173
secretory granule Hs cellular component 826 0.0
dendrite Hs cellular component 826 0.0
cytoplasmic vesicle Hs cellular component 826 0.0
secretory granule lumen Hs cellular component 826 0.0
peptide binding Hs molecular function 513 4.11e-173
identical protein binding Hs molecular function 481 3.50e-161
neuronal cell body Hs cellular component 826 0.0
perikaryon Hs cellular component 826 0.0
intracellular membrane-bounded organelle Hs cellular component 826 0.0
membrane raft Hs cellular component 513 4.11e-173
metal ion binding Hs molecular function 513 4.11e-173
nerve growth factor binding Hs molecular function 513 4.11e-173
extracellular exosome Hs cellular component 513 4.11e-173

GO (InterProScan)

2 results

GO Term Analysis Type e-value
serine-type endopeptidase activity Gene3D molecular function 1.9E-87
proteolysis Gene3D biological process 1.9E-87