Gene Card
Best human hits
SHMT1; SHMT2
Unique Gene ID
Cirobu.g00010974
Gene Model ID
KH2012:KH.L129.7
Location
KhL129:4840..9904
Transcript Models and Sequences
KH2012:KH.L129.7.v1.A.nonSL2-1
KH2012:KH.L129.7.v1.A.nonSL3-1
KH2012:KH.L129.7.v1.A.nonSL4-1
KH2012:KH.L129.7.v1.R.ND1-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000008186 |
cima891964
Plate: VES70_H24
cien133477
Plate: VES91_O04
cien199593
Plate: VES101_B06
cien220541
Plate: VES104_M11
cieg022i23
Plate: R1CiGC19a23
ciad075i04
Plate: R1CiGC07o24
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
PyrdxlP-dep_Trfase_dom1 | Gene3D | Pyridoxal phosphate-dependent transferase domain 1 |
PyrdxlP-dep_Trfase | SUPERFAMILY | Pyridoxal phosphate-dependent transferase |
Ser_HO-MeTrfase | CDD | Serine hydroxymethyltransferase |
Ser_HO-MeTrfase_PLP_BS | ProSitePatterns | Serine hydroxymethyltransferase, pyridoxal phosphate binding site |
Ser_HO-MeTrfase | PIRSF | Serine hydroxymethyltransferase |
Ser_HO-MeTrfase | Hamap | Serine hydroxymethyltransferase |
PyrdxlP-dep_Trfase_major | Gene3D | Pyridoxal phosphate-dependent transferase, major domain |
GO Term | Annotation Origin | Type |
---|---|---|
chromatin binding | Blast | molecular function |
catalytic activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
mitochondrial inner membrane | Blast | cellular component |
mitochondrial matrix | Blast | cellular component |
cytosol | Orthology | cellular component |
microtubule cytoskeleton | Blast | cellular component |
membrane | Blast | cellular component |
transferase activity | Orthology | molecular function |
identical protein binding | Orthology | molecular function |
protein homodimerization activity | Orthology | molecular function |
extracellular exosome | Orthology | cellular component |
negative regulation of gene expression | Orthology | biological process |
nucleic acid binding | Orthology | molecular function |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
phosphate-containing compound metabolic process | Orthology | biological process |
cellular metabolic process | Orthology | biological process |
cellular biosynthetic process | Orthology | biological process |
nucleobase-containing compound metabolic process | Orthology | biological process |
small molecule binding | Orthology | molecular function |
anion binding | Orthology | molecular function |
heterocyclic compound binding | Orthology | molecular function |
organic cyclic compound binding | Orthology | molecular function |
coenzyme binding | Orthology | molecular function |
cellular aromatic compound metabolic process | Orthology | biological process |
RNA binding | Orthology | molecular function |
protein oligomerization | Orthology | biological process |
protein homooligomerization | Orthology | biological process |
cation binding | Orthology | molecular function |
mitochondrial envelope | Blast | cellular component |
intracellular organelle lumen | Blast | cellular component |
metabolic process | Blast | biological process |
intracellular non-membrane-bounded organelle | Blast | cellular component |
nuclear part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
translation repressor activity, nucleic acid binding | Hs | molecular function |
catalytic activity | Hs | molecular function |
glycine hydroxymethyltransferase activity | Hs | molecular function |
thiol-dependent ubiquitin-specific protease activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
mitochondrion | Hs | cellular component |
cytosol | Hs | cellular component |
dTMP biosynthetic process | Hs | biological process |
glycine metabolic process | Hs | biological process |
glycine biosynthetic process | Hs | biological process |
L-serine metabolic process | Hs | biological process |
one-carbon metabolic process | Hs | biological process |
L-allo-threonine aldolase activity | Hs | molecular function |
purine nucleobase biosynthetic process | Hs | biological process |
protein deubiquitination | Hs | biological process |
amino acid binding | Hs | molecular function |
transferase activity | Hs | molecular function |
negative regulation of translation | Hs | biological process |
glycine biosynthetic process from serine | Hs | biological process |
pyridoxal phosphate binding | Hs | molecular function |
tetrahydrofolate interconversion | Hs | biological process |
identical protein binding | Hs | molecular function |
protein homodimerization activity | Hs | molecular function |
carnitine biosynthetic process | Hs | biological process |
tetrahydrofolate metabolic process | Hs | biological process |
folic acid metabolic process | Hs | biological process |
mRNA 5'-UTR binding | Hs | molecular function |
protein tetramerization | Hs | biological process |
protein homotetramerization | Hs | biological process |
extracellular exosome | Hs | cellular component |
serine binding | Hs | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
translation repressor activity, nucleic acid binding | Hs | molecular function | 655 | 0.0 |
chromatin binding | Hs | molecular function | 596 | 0.0 |
catalytic activity | Hs | molecular function | 655 | 0.0 |
glycine hydroxymethyltransferase activity | Hs | molecular function | 655 | 0.0 |
thiol-dependent ubiquitin-specific protease activity | Hs | molecular function | 655 | 0.0 |
protein binding | Hs | molecular function | 655 | 0.0 |
nucleus | Hs | cellular component | 655 | 0.0 |
cytoplasm | Hs | cellular component | 655 | 0.0 |
mitochondrion | Hs | cellular component | 655 | 0.0 |
mitochondrial inner membrane | Hs | cellular component | 596 | 0.0 |
mitochondrial intermembrane space | Hs | cellular component | 596 | 0.0 |
mitochondrial matrix | Hs | cellular component | 596 | 0.0 |
cytosol | Hs | cellular component | 655 | 0.0 |
methyltransferase activity | Hs | molecular function | 596 | 0.0 |
L-allo-threonine aldolase activity | Hs | molecular function | 655 | 0.0 |
microtubule cytoskeleton | Hs | cellular component | 596 | 0.0 |
membrane | Hs | cellular component | 596 | 0.0 |
amino acid binding | Hs | molecular function | 655 | 0.0 |
transferase activity | Hs | molecular function | 655 | 0.0 |
pyridoxal phosphate binding | Hs | molecular function | 655 | 0.0 |
mitochondrial nucleoid | Hs | cellular component | 596 | 0.0 |
identical protein binding | Hs | molecular function | 655 | 0.0 |
protein homodimerization activity | Hs | molecular function | 655 | 0.0 |
mRNA 5'-UTR binding | Hs | molecular function | 655 | 0.0 |
extracellular exosome | Hs | cellular component | 655 | 0.0 |
BRISC complex | Hs | cellular component | 596 | 0.0 |
serine binding | Hs | molecular function | 655 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
catalytic activity | Gene3D | molecular function | 9.6E-209 |
glycine hydroxymethyltransferase activity | CDD | molecular function | 0.0 |
glycine biosynthetic process from serine | CDD | biological process | 0.0 |
pyridoxal phosphate binding | CDD | molecular function | 0.0 |
tetrahydrofolate interconversion | CDD | biological process | 0.0 |