Gene Card
Best human hits
CTSD; CTSE; REN
Unique Gene ID
Cirobu.g00011470
Gene Model ID
KH2012:KH.L153.21
Location
KhL153:511702..516745
Transcript Models and Sequences
KH2012:KH.L153.21.v1.R.ND1-1
KH2012:KH.L153.21.v2.A.nonSL11-1
KH2012:KH.L153.21.v2.A.nonSL12-1
KH2012:KH.L153.21.v2.A.nonSL14-1
KH2012:KH.L153.21.v2.A.nonSL4-1
KH2012:KH.L153.21.v2.A.nonSL5-1
KH2012:KH.L153.21.v2.A.nonSL7-1
KH2012:KH.L153.21.v2.A.nonSL8-1
KH2012:KH.L153.21.v2.A.SL10-1
KH2012:KH.L153.21.v2.A.SL13-1
KH2012:KH.L153.21.v2.A.SL2-1
KH2012:KH.L153.21.v2.A.SL3-1
KH2012:KH.L153.21.v2.A.SL9-1
KH2012:KH.L153.21.v3.A.SL6-1
cima89415
Plate: VES57_K18
cima824557
Plate: VES60_J17
cien148828
Plate: VES93_K12
cien172392
Plate: VES96_F23
n/a
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IPR Term | Analysis | Definition |
---|---|---|
2Fe-2S_ferredoxin-type | CDD | 2Fe-2S ferredoxin-type iron-sulfur binding domain |
Adrenodoxin | PRINTS | Adrenodoxin |
Adrenodoxin_Fe-S_BS | ProSitePatterns | Adrenodoxin, iron-sulphur binding site |
2Fe-2S_ferredoxin-type | Pfam | 2Fe-2S ferredoxin-type iron-sulfur binding domain |
2Fe-2S_ferredoxin-like_sf | SUPERFAMILY | 2Fe-2S ferredoxin-like superfamily |
Beta-grasp_dom_sf | Gene3D | Beta-grasp domain superfamily |
2Fe-2S_ferredoxin-type | ProSiteProfiles | 2Fe-2S ferredoxin-type iron-sulfur binding domain |
Aspartic_peptidase_AS | ProSitePatterns | Aspartic peptidase, active site |
Peptidase_aspartic_dom_sf | Gene3D | Aspartic peptidase domain superfamily |
Peptidase_aspartic_dom_sf | SUPERFAMILY | Aspartic peptidase domain superfamily |
PEPTIDASE_A1 | Pfam | Peptidase family A1 domain |
PEPTIDASE_A1 | ProSiteProfiles | Peptidase family A1 domain |
Aspartic_peptidase_A1 | PRINTS | Aspartic peptidase A1 family |
Aspartic_peptidase_A1 | PANTHER | Aspartic peptidase A1 family |
GO Term | Annotation Origin | Type |
---|---|---|
endopeptidase activity | Orthology | molecular function |
serine-type endopeptidase activity | Orthology | molecular function |
receptor binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
extracellular region | Orthology | cellular component |
extracellular space | Orthology | cellular component |
intracellular | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
lysosome | Orthology | cellular component |
endosome | Blast | cellular component |
plasma membrane | Orthology | cellular component |
proteolysis | Orthology | biological process |
peptidase activity | Orthology | molecular function |
response to organic substance | Orthology | biological process |
membrane | Orthology | cellular component |
hydrolase activity | Orthology | molecular function |
response to lipopolysaccharide | Orthology | biological process |
melanosome | Orthology | cellular component |
protein homodimerization activity | Blast | molecular function |
membrane raft | Orthology | cellular component |
apical part of cell | Orthology | cellular component |
extracellular exosome | Orthology | cellular component |
response to biotic stimulus | Orthology | biological process |
integral component of membrane | Orthology | cellular component |
animal organ development | Orthology | biological process |
peptide metabolic process | Orthology | biological process |
gene expression | Orthology | biological process |
reproductive process | Orthology | biological process |
signal transduction | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
immune system process | Orthology | biological process |
protein metabolic process | Orthology | biological process |
catabolic process | Orthology | biological process |
extracellular region part | Orthology | cellular component |
intracellular organelle part | Orthology | cellular component |
cytoplasmic vesicle | Orthology | cellular component |
endomembrane system | Orthology | cellular component |
intracellular organelle lumen | Orthology | cellular component |
vacuolar part | Orthology | cellular component |
intracellular signal transduction | Orthology | biological process |
regulation of signal transduction | Orthology | biological process |
regulation of cellular metabolic process | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
cellular metabolic process | InterProScan | biological process |
oxidation-reduction process | InterProScan | biological process |
catalytic activity | InterProScan | molecular function |
cofactor binding | InterProScan | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
kidney development | Hs | biological process |
angiotensin maturation | Hs | biological process |
endopeptidase activity | Hs | molecular function |
aspartic-type endopeptidase activity | Hs | molecular function |
cysteine-type endopeptidase activity | Hs | molecular function |
serine-type endopeptidase activity | Hs | molecular function |
receptor binding | Hs | molecular function |
insulin-like growth factor receptor binding | Hs | molecular function |
protein binding | Hs | molecular function |
extracellular region | Hs | cellular component |
extracellular space | Hs | cellular component |
intracellular | Hs | cellular component |
cytoplasm | Hs | cellular component |
lysosome | Hs | cellular component |
plasma membrane | Hs | cellular component |
proteolysis | Hs | biological process |
autophagy | Hs | biological process |
regulation of blood pressure | Hs | biological process |
peptidase activity | Hs | molecular function |
male gonad development | Hs | biological process |
hormone-mediated signaling pathway | Hs | biological process |
response to organic substance | Hs | biological process |
membrane | Hs | cellular component |
hydrolase activity | Hs | molecular function |
antigen processing and presentation of exogenous peptide antigen via MHC class II | Hs | biological process |
protein catabolic process | Hs | biological process |
collagen catabolic process | Hs | biological process |
extracellular matrix | Hs | cellular component |
response to lipopolysaccharide | Hs | biological process |
specific granule lumen | Hs | cellular component |
melanosome | Hs | cellular component |
response to drug | Hs | biological process |
drinking behavior | Hs | biological process |
lysosomal lumen | Hs | cellular component |
regulation of MAPK cascade | Hs | biological process |
membrane raft | Hs | cellular component |
apical part of cell | Hs | cellular component |
amyloid-beta metabolic process | Hs | biological process |
response to cAMP | Hs | biological process |
extracellular exosome | Hs | cellular component |
tertiary granule lumen | Hs | cellular component |
ficolin-1-rich granule lumen | Hs | cellular component |
response to biotic stimulus | Hs | biological process |
integral component of membrane | Hs | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
endopeptidase activity | Hs | molecular function | 349 | 2.54e-118 |
aspartic-type endopeptidase activity | Hs | molecular function | 445 | 4.75e-156 |
cysteine-type endopeptidase activity | Hs | molecular function | 445 | 4.75e-156 |
serine-type endopeptidase activity | Hs | molecular function | 445 | 4.75e-156 |
receptor binding | Hs | molecular function | 349 | 2.54e-118 |
insulin-like growth factor receptor binding | Hs | molecular function | 349 | 2.54e-118 |
protein binding | Hs | molecular function | 445 | 4.75e-156 |
extracellular region | Hs | cellular component | 445 | 4.75e-156 |
extracellular space | Hs | cellular component | 445 | 4.75e-156 |
intracellular | Hs | cellular component | 349 | 2.54e-118 |
cytoplasm | Hs | cellular component | 349 | 2.54e-118 |
lysosome | Hs | cellular component | 445 | 4.75e-156 |
endosome | Hs | cellular component | 369 | 3.80e-126 |
plasma membrane | Hs | cellular component | 349 | 2.54e-118 |
peptidase activity | Hs | molecular function | 445 | 4.75e-156 |
membrane | Hs | cellular component | 349 | 2.54e-118 |
hydrolase activity | Hs | molecular function | 445 | 4.75e-156 |
extracellular matrix | Hs | cellular component | 445 | 4.75e-156 |
specific granule lumen | Hs | cellular component | 445 | 4.75e-156 |
melanosome | Hs | cellular component | 445 | 4.75e-156 |
protein homodimerization activity | Hs | molecular function | 369 | 3.80e-126 |
lysosomal lumen | Hs | cellular component | 445 | 4.75e-156 |
membrane raft | Hs | cellular component | 445 | 4.75e-156 |
apical part of cell | Hs | cellular component | 349 | 2.54e-118 |
extracellular exosome | Hs | cellular component | 445 | 4.75e-156 |
tertiary granule lumen | Hs | cellular component | 445 | 4.75e-156 |
ficolin-1-rich granule lumen | Hs | cellular component | 445 | 4.75e-156 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
aspartic-type endopeptidase activity | PANTHER | molecular function | 1.8E-150 |
proteolysis | PANTHER | biological process | 1.8E-150 |
electron carrier activity | SUPERFAMILY | molecular function | 1.1E-25 |
iron-sulfur cluster binding | SUPERFAMILY | molecular function | 1.1E-25 |