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GENE CARD

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Gene Card

Best human hits

DLL1; DLL4

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00011628

Gene Model ID

KH2012:KH.L155.7

Location

KhL155:23280..28969

Transcript Models and Sequences

  KH2012:KH.L155.7.v1.A.SL1-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000004194
NCBI Reference Sequence NM_001078209.1
Collections

Gateway full ORF

4 results

cien100488

Plate: VES85_E23

cien43954

Plate: VES77_C07

cien148562

Plate: VES93_D11

cien224920

Plate: VES105_G02

Gene collection 1 (N. Satoh)

1 result

cicl011j01

Plate: R1CiGC09b02

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
EGF-like_CS ProSitePatterns EGF-like, conserved site
DSL Pfam Delta/Serrate/lag-2 (DSL) protein
DSL ProSiteProfiles Delta/Serrate/lag-2 (DSL) protein
Notch_ligand_N Pfam Notch ligand, N-terminal domain
EGF-type_Asp/Asn_hydroxyl_site ProSitePatterns EGF-type aspartate/asparagine hydroxylation site
EGF-like_dom ProSiteProfiles EGF-like domain
EGF-like_CS Pfam EGF-like, conserved site
EGF-like_dom SMART EGF-like domain
EGF-like_dom Pfam EGF-like domain
EGF-like_Ca-bd_dom SMART EGF-like calcium-binding domain
DSL SMART Delta/Serrate/lag-2 (DSL) protein

GOSlim

57 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
angiogenesis Orthology biological process
calcium ion binding Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Orthology cellular component
adherens junction Orthology cellular component
cell communication Orthology biological process
signal transduction Orthology biological process
Notch signaling pathway Orthology biological process
cell-cell signaling Orthology biological process
multicellular organism development Orthology biological process
nervous system development Orthology biological process
visual perception Orthology biological process
positive regulation of cell proliferation Orthology biological process
negative regulation of cell proliferation Orthology biological process
positive regulation of gene expression Orthology biological process
negative regulation of gene expression Orthology biological process
membrane Orthology cellular component
integral component of membrane Orthology cellular component
apical plasma membrane Orthology cellular component
cell junction Orthology cellular component
cell differentiation Orthology biological process
cytoplasmic vesicle Orthology cellular component
membrane raft Orthology cellular component
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
response to stimulus Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
heart development Orthology biological process
anatomical structure morphogenesis Orthology biological process
cell development Orthology biological process
animal organ development Orthology biological process
receptor binding Orthology molecular function
neurogenesis Orthology biological process
central nervous system development Orthology biological process
brain development Orthology biological process
immune system process Orthology biological process
cell adhesion Orthology biological process
transcription factor binding Orthology molecular function
negative regulation of apoptotic process Orthology biological process
developmental process Orthology biological process
blood vessel morphogenesis Orthology biological process
cellular response to organic substance Orthology biological process
cell migration Orthology biological process
neuron differentiation Orthology biological process
negative regulation of signal transduction Orthology biological process
positive regulation of signal transduction Orthology biological process
membrane organization Orthology biological process
organelle organization Orthology biological process
generation of neurons Orthology biological process
cell division Orthology biological process
blood vessel development Orthology biological process
cell surface receptor signaling pathway Orthology biological process
regulation of signal transduction Orthology biological process
system development Orthology biological process
anatomical structure development Orthology biological process

GO (Orthology)

89 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
angiogenesis Hs biological process
branching involved in blood vessel morphogenesis Hs biological process
cell fate determination Hs biological process
somitogenesis Hs biological process
somite specification Hs biological process
heart looping Hs biological process
cardiac ventricle morphogenesis Hs biological process
cardiac atrium morphogenesis Hs biological process
ventricular trabecula myocardium morphogenesis Hs biological process
type B pancreatic cell development Hs biological process
pericardium morphogenesis Hs biological process
Notch binding Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
adherens junction Hs cellular component
cell communication Hs biological process
signal transduction Hs biological process
Notch signaling pathway Hs biological process
Notch receptor processing Hs biological process
cell-cell signaling Hs biological process
multicellular organism development Hs biological process
determination of left/right symmetry Hs biological process
compartment pattern specification Hs biological process
nervous system development Hs biological process
visual perception Hs biological process
blood circulation Hs biological process
regulation of blood pressure Hs biological process
positive regulation of cell proliferation Hs biological process
negative regulation of cell proliferation Hs biological process
proximal/distal pattern formation Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of gene expression Hs biological process
astrocyte development Hs biological process
regulation of somitogenesis Hs biological process
membrane Hs cellular component
integral component of membrane Hs cellular component
apical plasma membrane Hs cellular component
spinal cord development Hs biological process
cerebellar Purkinje cell layer structural organization Hs biological process
cell junction Hs cellular component
hemopoiesis Hs biological process
cell differentiation Hs biological process
regulation of cell adhesion Hs biological process
T cell differentiation Hs biological process
Tat protein binding Hs molecular function
cytoplasmic vesicle Hs cellular component
negative regulation of glial cell apoptotic process Hs biological process
organ growth Hs biological process
dorsal aorta morphogenesis Hs biological process
cellular response to vascular endothelial growth factor stimulus Hs biological process
regulation of growth Hs biological process
negative regulation of blood vessel endothelial cell migration Hs biological process
membrane raft Hs cellular component
negative regulation of cell differentiation Hs biological process
negative regulation of epidermal cell differentiation Hs biological process
negative regulation of myeloid cell differentiation Hs biological process
negative regulation of neuron differentiation Hs biological process
negative regulation of Notch signaling pathway Hs biological process
positive regulation of Notch signaling pathway Hs biological process
positive regulation of endocytosis Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
lateral inhibition Hs biological process
neuron fate specification Hs biological process
inner ear development Hs biological process
regulation of neurogenesis Hs biological process
response to stimulus Hs biological process
regulation of cell division Hs biological process
retina development in camera-type eye Hs biological process
retina morphogenesis in camera-type eye Hs biological process
ventral spinal cord interneuron fate commitment Hs biological process
Notch signaling pathway involved in arterial endothelial cell fate commitment Hs biological process
regulation of neural retina development Hs biological process
left/right axis specification Hs biological process
blood vessel lumenization Hs biological process
clathrin-dependent endocytosis Hs biological process
scaffold protein binding Hs molecular function
neuronal stem cell population maintenance Hs biological process
skin epidermis development Hs biological process
regulation of vascular endothelial growth factor signaling pathway Hs biological process
positive regulation of sprouting angiogenesis Hs biological process
positive regulation of neural precursor cell proliferation Hs biological process
skeletal system development Hs biological process
tissue development Hs biological process
paraxial mesoderm development Hs biological process
negative regulation of neurogenesis Hs biological process

GO (Blast)

15 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
Notch binding Hs molecular function 422 2.95e-138
calcium ion binding Hs molecular function 422 2.95e-138
protein binding Hs molecular function 422 2.95e-138
extracellular region Hs cellular component 422 2.95e-138
plasma membrane Hs cellular component 422 2.95e-138
integral component of plasma membrane Hs cellular component 422 2.95e-138
adherens junction Hs cellular component 422 2.95e-138
membrane Hs cellular component 422 2.95e-138
integral component of membrane Hs cellular component 422 2.95e-138
apical plasma membrane Hs cellular component 422 2.95e-138
cell junction Hs cellular component 422 2.95e-138
Tat protein binding Hs molecular function 422 2.95e-138
cytoplasmic vesicle Hs cellular component 422 2.95e-138
membrane raft Hs cellular component 422 2.95e-138
scaffold protein binding Hs molecular function 422 2.95e-138

GO (InterProScan)

6 results

GO Term Analysis Type e-value
calcium ion binding SMART molecular function 1.4E-9
cell communication Pfam biological process 2.0E-18
Notch signaling pathway Pfam biological process 1.7E-22
multicellular organism development Pfam biological process 1.7E-22
membrane Pfam cellular component 2.0E-18
integral component of membrane Pfam cellular component 1.7E-22

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