Login
Help

GENE CARD

Submit your Data

Gene Card

Best human hits

ARAF; BRAF; RAF1

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00011956

Gene Model ID

KH2012:KH.L18.20

Location

KhL18:560952..572004

Transcript Models and Sequences

  KH2012:KH.L18.20.v1.A.SL1-2
KH2012:KH.L18.20.v1.A.SL2-2
KH2012:KH.L18.20.v1.A.SL4-2
KH2012:KH.L18.20.v1.A.SL6-2
KH2012:KH.L18.20.v2.A.SL1-1
KH2012:KH.L18.20.v2.A.SL2-1
KH2012:KH.L18.20.v2.A.SL4-1
KH2012:KH.L18.20.v2.A.SL6-1
KH2012:KH.L18.20.v3.A.ND5-2
KH2012:KH.L18.20.v4.A.SL3-1
KH2012:KH.L18.20.v5.A.SL1-2
KH2012:KH.L18.20.v5.A.SL2-2
KH2012:KH.L18.20.v5.A.SL4-2
KH2012:KH.L18.20.v5.A.SL6-2
KH2012:KH.L18.20.v6.A.SL3-2
KH2012:KH.L18.20.v7.A.SL3-2

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000003721
NCBI Reference Sequence NM_001078337.1
Collections

Gateway full ORF

2 results

cien121481

Plate: VES89_N06

cien188257

Plate: VES99_A10

Gene collection 1 (N. Satoh)

2 results

citb5a16

Plate: R1CiGC29a22

cilv076n12

Plate: R1CiGC44f13

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
 Click here to see how you can interact with this tree
 Click here to see the tree inference method

Gene Annotations

InterPro

13 results

IPR Term Analysis Definition
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Prot_kinase_dom Pfam Protein kinase domain
PE/DAG-bd ProSitePatterns Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
PE/DAG-bd SMART Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site
PE/DAG-bd CDD Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
RBD_dom Pfam Raf-like Ras-binding
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Prot_kinase_dom SMART Protein kinase domain
PE/DAG-bd ProSiteProfiles Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
PE/DAG-bd Pfam Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Ubiquitin-like_domsf SUPERFAMILY Ubiquitin-like domain superfamily
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily

GOSlim

88 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
response to hypoxia Orthology biological process
protein kinase activity Orthology molecular function
protein serine/threonine kinase activity Orthology molecular function
calcium ion binding Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
intracellular Orthology cellular component
nucleus Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Orthology cellular component
Golgi apparatus Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
cellular protein modification process Orthology biological process
protein phosphorylation Orthology biological process
apoptotic process Orthology biological process
signal transduction Orthology biological process
multicellular organism development Orthology biological process
heart development Orthology biological process
cell proliferation Orthology biological process
negative regulation of cell proliferation Orthology biological process
negative regulation of signal transduction Orthology biological process
positive regulation of gene expression Orthology biological process
membrane Orthology cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
nuclear speck Orthology cellular component
transferase activity Orthology molecular function
enzyme binding Orthology molecular function
cell differentiation Orthology biological process
intracellular signal transduction Orthology biological process
wound healing Orthology biological process
regulation of cell proliferation Orthology biological process
identical protein binding Orthology molecular function
regulation of apoptotic process Orthology biological process
neuron projection Orthology cellular component
negative regulation of apoptotic process Orthology biological process
positive regulation of catalytic activity Orthology biological process
intracellular membrane-bounded organelle Orthology cellular component
cell body Orthology cellular component
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
protein heterodimerization activity Orthology molecular function
establishment of protein localization to membrane Orthology biological process
positive regulation of signal transduction Orthology biological process
cellular process Orthology biological process
cell Orthology cellular component
whole membrane Orthology cellular component
mitochondrial membrane Orthology cellular component
bounding membrane of organelle Orthology cellular component
regulation of catalytic activity Orthology biological process
nervous system process Orthology biological process
animal organ development Orthology biological process
anatomical structure morphogenesis Orthology biological process
enzyme activator activity Orthology molecular function
blood coagulation Orthology biological process
cell projection Orthology cellular component
plasma membrane region Orthology cellular component
protein kinase binding Orthology molecular function
regulation of signal transduction Orthology biological process
regulation of cellular metabolic process Orthology biological process
proteolysis Orthology biological process
ion transport Orthology biological process
transmembrane transport Orthology biological process
developmental process Orthology biological process
small GTPase mediated signal transduction Orthology biological process
endopeptidase activity Orthology molecular function
immune system process Orthology biological process
response to organic substance Orthology biological process
organelle organization Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cellular response to organic substance Orthology biological process
axon development Orthology biological process
cellular response to stress Orthology biological process
response to wounding Orthology biological process
axonogenesis Orthology biological process
immune response Orthology biological process
protein oligomerization Orthology biological process
chemical synaptic transmission Orthology biological process
head development Orthology biological process
cell morphogenesis involved in differentiation Orthology biological process
cell adhesion Orthology biological process
cell motility Orthology biological process
synapse part Orthology cellular component
intracellular transport Orthology biological process
neuron part Orthology cellular component
membrane organization Orthology biological process

GO (Orthology)

95 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
MAPK cascade Hs biological process
nucleotide binding Hs molecular function
activation of MAPKK activity Hs biological process
response to hypoxia Hs biological process
cellular glucose homeostasis Hs biological process
positive regulation of protein phosphorylation Hs biological process
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
MAP kinase kinase kinase activity Hs molecular function
signal transducer activity, downstream of receptor Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
mitochondrial outer membrane Hs cellular component
Golgi apparatus Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
cellular protein modification process Hs biological process
protein phosphorylation Hs biological process
apoptotic process Hs biological process
signal transduction Hs biological process
activation of adenylate cyclase activity Hs biological process
multicellular organism development Hs biological process
heart development Hs biological process
adenylate cyclase binding Hs molecular function
cell proliferation Hs biological process
negative regulation of cell proliferation Hs biological process
visual learning Hs biological process
animal organ morphogenesis Hs biological process
negative regulation of signal transduction Hs biological process
positive regulation of gene expression Hs biological process
adenylate cyclase activator activity Hs molecular function
membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
nuclear speck Hs cellular component
transferase activity Hs molecular function
Ras GTPase binding Hs molecular function
enzyme binding Hs molecular function
cell differentiation Hs biological process
platelet activation Hs biological process
thyroid gland development Hs biological process
pseudopodium Hs cellular component
negative regulation of protein complex assembly Hs biological process
mitogen-activated protein kinase kinase binding Hs molecular function
regulation of TOR signaling Hs biological process
regulation of proteasomal ubiquitin-dependent protein catabolic process Hs biological process
positive regulation of peptidyl-serine phosphorylation Hs biological process
ion transmembrane transport Hs biological process
somatic stem cell population maintenance Hs biological process
regulation of Rho protein signal transduction Hs biological process
intracellular signal transduction Hs biological process
wound healing Hs biological process
regulation of cell proliferation Hs biological process
identical protein binding Hs molecular function
regulation of apoptotic process Hs biological process
neuron projection Hs cellular component
negative regulation of apoptotic process Hs biological process
positive regulation of catalytic activity Hs biological process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
intracellular membrane-bounded organelle Hs cellular component
positive T cell selection Hs biological process
response to peptide hormone Hs biological process
negative regulation of neuron apoptotic process Hs biological process
cell body Hs cellular component
intermediate filament cytoskeleton organization Hs biological process
regulation of T cell differentiation Hs biological process
regulation of cell differentiation Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
alpha-beta T cell differentiation Hs biological process
metal ion binding Hs molecular function
protein heterodimerization activity Hs molecular function
neurotrophin TRK receptor signaling pathway Hs biological process
thymus development Hs biological process
regulation of axon regeneration Hs biological process
positive regulation of axon regeneration Hs biological process
positive regulation of axonogenesis Hs biological process
T cell receptor signaling pathway Hs biological process
protein heterooligomerization Hs biological process
positive regulation of stress fiber assembly Hs biological process
response to cAMP Hs biological process
long-term synaptic potentiation Hs biological process
head morphogenesis Hs biological process
face development Hs biological process
positive regulation of ERK1 and ERK2 cascade Hs biological process
cellular response to calcium ion Hs biological process
establishment of protein localization to membrane Hs biological process
positive regulation of substrate adhesion-dependent cell spreading Hs biological process
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors Hs biological process
regulation of cell motility Hs biological process
negative regulation of synaptic vesicle exocytosis Hs biological process

GO (Blast)

32 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 558 0.0
protein kinase activity Hs molecular function 558 0.0
protein serine/threonine kinase activity Hs molecular function 558 0.0
MAP kinase kinase kinase activity Hs molecular function 558 0.0
signal transducer activity, downstream of receptor Hs molecular function 558 0.0
calcium ion binding Hs molecular function 558 0.0
protein binding Hs molecular function 558 0.0
ATP binding Hs molecular function 558 0.0
intracellular Hs cellular component 558 0.0
nucleus Hs cellular component 558 0.0
cytoplasm Hs cellular component 558 0.0
mitochondrion Hs cellular component 558 0.0
mitochondrial outer membrane Hs cellular component 497 1.76e-167
Golgi apparatus Hs cellular component 497 1.76e-167
cytosol Hs cellular component 558 0.0
plasma membrane Hs cellular component 558 0.0
adenylate cyclase binding Hs molecular function 497 1.76e-167
adenylate cyclase activator activity Hs molecular function 497 1.76e-167
membrane Hs cellular component 558 0.0
kinase activity Hs molecular function 558 0.0
nuclear speck Hs cellular component 497 1.76e-167
transferase activity Hs molecular function 558 0.0
Ras GTPase binding Hs molecular function 558 0.0
enzyme binding Hs molecular function 497 1.76e-167
pseudopodium Hs cellular component 497 1.76e-167
mitogen-activated protein kinase kinase binding Hs molecular function 558 0.0
identical protein binding Hs molecular function 558 0.0
neuron projection Hs cellular component 558 0.0
intracellular membrane-bounded organelle Hs cellular component 558 0.0
cell body Hs cellular component 558 0.0
metal ion binding Hs molecular function 558 0.0
protein heterodimerization activity Hs molecular function 558 0.0

GO (InterProScan)

6 results

GO Term Analysis Type e-value
protein kinase activity SMART molecular function 5.0E-60
signal transducer activity, downstream of receptor Pfam molecular function 3.2E-8
ATP binding SMART molecular function 5.0E-60
protein phosphorylation SMART biological process 5.0E-60
signal transduction Pfam biological process 3.2E-8
intracellular signal transduction CDD biological process 1.3437E-11

Back to Top