Gene Card
Best human hits
ILKAP; PPM1K; TAB1
Unique Gene ID
Cirobu.g00012205
Gene Model ID
KH2012:KH.L23.9
Location
KhL23:78174..83726
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000003713 |
cima861138
Plate: VES64_L19
cima866019
Plate: VES65_F19
citb9e12
Plate: R1CiGC29p22
cicl050m01
Plate: R1CiGC13n04
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
PP2C | PANTHER | Protein phosphatase 2C family |
PPM-type_phosphatase_dom | SMART | PPM-type phosphatase domain |
PPM-type_phosphatase_dom | Pfam | PPM-type phosphatase domain |
PPM-type_dom_sf | SUPERFAMILY | PPM-type phosphatase domain superfamily |
PPM-type_dom_sf | Gene3D | PPM-type phosphatase domain superfamily |
PPM-type_phosphatase_dom | CDD | PPM-type phosphatase domain |
PPM-type_phosphatase_dom | ProSiteProfiles | PPM-type phosphatase domain |
GO Term | Annotation Origin | Type |
---|---|---|
catalytic activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Blast | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Blast | cellular component |
mitochondrion | Blast | cellular component |
mitochondrial matrix | Blast | cellular component |
cytosol | Orthology | cellular component |
protein dephosphorylation | Orthology | biological process |
enzyme activator activity | Orthology | molecular function |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
nuclear speck | Orthology | cellular component |
hydrolase activity | Orthology | molecular function |
cation binding | Blast | molecular function |
metal ion binding | Blast | molecular function |
positive regulation of catalytic activity | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
protein serine/threonine kinase activity | Orthology | molecular function |
positive regulation of signal transduction | Orthology | biological process |
signal transduction | Orthology | biological process |
innate immune response | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
heart development | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
cellular response to stress | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
whole membrane | Orthology | cellular component |
endosome | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
animal organ development | Orthology | biological process |
blood vessel development | Orthology | biological process |
immune response | Orthology | biological process |
protein kinase binding | Orthology | molecular function |
cytokine-mediated signaling pathway | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
activation of MAPKKK activity | Hs | biological process |
activation of MAPK activity | Hs | biological process |
MyD88-dependent toll-like receptor signaling pathway | Hs | biological process |
heart morphogenesis | Hs | biological process |
catalytic activity | Hs | molecular function |
protein serine/threonine phosphatase activity | Hs | molecular function |
protein binding | Hs | molecular function |
cytosol | Hs | cellular component |
protein dephosphorylation | Hs | biological process |
transforming growth factor beta receptor signaling pathway | Hs | biological process |
I-kappaB kinase/NF-kappaB signaling | Hs | biological process |
JNK cascade | Hs | biological process |
enzyme activator activity | Hs | molecular function |
endosome membrane | Hs | cellular component |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
protein deubiquitination | Hs | biological process |
nuclear speck | Hs | cellular component |
kinase activator activity | Hs | molecular function |
lung development | Hs | biological process |
aorta development | Hs | biological process |
Fc-epsilon receptor signaling pathway | Hs | biological process |
positive regulation of MAP kinase activity | Hs | biological process |
mitogen-activated protein kinase p38 binding | Hs | molecular function |
positive regulation of NF-kappaB transcription factor activity | Hs | biological process |
coronary vasculature development | Hs | biological process |
interleukin-1-mediated signaling pathway | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
catalytic activity | Hs | molecular function | 332 | 1.14e-108 |
phosphoprotein phosphatase activity | Hs | molecular function | 62.8 | 1.52e-10 |
protein serine/threonine phosphatase activity | Hs | molecular function | 332 | 1.14e-108 |
protein binding | Hs | molecular function | 332 | 1.14e-108 |
nucleus | Hs | cellular component | 62.8 | 1.52e-10 |
nucleoplasm | Hs | cellular component | 62.8 | 1.52e-10 |
cytoplasm | Hs | cellular component | 62.8 | 1.52e-10 |
mitochondrion | Hs | cellular component | 62.0 | 2.31e-10 |
mitochondrial matrix | Hs | cellular component | 62.0 | 2.31e-10 |
cytosol | Hs | cellular component | 332 | 1.14e-108 |
enzyme activator activity | Hs | molecular function | 332 | 1.14e-108 |
endosome membrane | Hs | cellular component | 332 | 1.14e-108 |
kinase activity | Hs | molecular function | 332 | 1.14e-108 |
nuclear speck | Hs | cellular component | 332 | 1.14e-108 |
hydrolase activity | Hs | molecular function | 62.8 | 1.52e-10 |
kinase activator activity | Hs | molecular function | 332 | 1.14e-108 |
cation binding | Hs | molecular function | 62.8 | 1.52e-10 |
metal ion binding | Hs | molecular function | 62.8 | 1.52e-10 |
mitogen-activated protein kinase p38 binding | Hs | molecular function | 332 | 1.14e-108 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
catalytic activity | CDD | molecular function | 4.98658E-43 |
protein serine/threonine phosphatase activity | PANTHER | molecular function | 1.5E-135 |
protein dephosphorylation | PANTHER | biological process | 1.5E-135 |