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GENE CARD

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Gene Card

Best human hits

ILKAP; PPM1K; TAB1

Unique Gene ID

Cirobu.g00012205

Gene Model ID

KH2012:KH.L23.9

Location

KhL23:78174..83726

External Database Gene Card

External database links

1 result

Database Gene ID
ENSEMBL ENSCING00000003713
Collections

Gateway full ORF

2 results

cima861138

Plate: VES64_L19

cima866019

Plate: VES65_F19

Gene collection 1 (N. Satoh)

2 results

citb9e12

Plate: R1CiGC29p22

cicl050m01

Plate: R1CiGC13n04

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
PP2C PANTHER Protein phosphatase 2C family
PPM-type_phosphatase_dom SMART PPM-type phosphatase domain
PPM-type_phosphatase_dom Pfam PPM-type phosphatase domain
PPM-type_dom_sf SUPERFAMILY PPM-type phosphatase domain superfamily
PPM-type_dom_sf Gene3D PPM-type phosphatase domain superfamily
PPM-type_phosphatase_dom CDD PPM-type phosphatase domain
PPM-type_phosphatase_dom ProSiteProfiles PPM-type phosphatase domain

GOSlim

39 results

GO Term Annotation Origin Type
catalytic activity Orthology molecular function
protein binding Orthology molecular function
nucleus Blast cellular component
nucleoplasm Blast cellular component
cytoplasm Blast cellular component
mitochondrion Blast cellular component
mitochondrial matrix Blast cellular component
cytosol Orthology cellular component
protein dephosphorylation Orthology biological process
enzyme activator activity Orthology molecular function
kinase activity Orthology molecular function
phosphorylation Orthology biological process
nuclear speck Orthology cellular component
hydrolase activity Orthology molecular function
cation binding Blast molecular function
metal ion binding Blast molecular function
positive regulation of catalytic activity Orthology biological process
intracellular signal transduction Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
positive regulation of signal transduction Orthology biological process
signal transduction Orthology biological process
innate immune response Orthology biological process
anatomical structure morphogenesis Orthology biological process
heart development Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cellular response to organic substance Orthology biological process
transcription factor activity, sequence-specific DNA binding Orthology molecular function
cellular response to stress Orthology biological process
protein phosphorylation Orthology biological process
intracellular organelle part Orthology cellular component
whole membrane Orthology cellular component
endosome Orthology cellular component
bounding membrane of organelle Orthology cellular component
peptidase activity, acting on L-amino acid peptides Orthology molecular function
animal organ development Orthology biological process
blood vessel development Orthology biological process
immune response Orthology biological process
protein kinase binding Orthology molecular function
cytokine-mediated signaling pathway Orthology biological process

GO (Orthology)

27 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
activation of MAPKKK activity Hs biological process
activation of MAPK activity Hs biological process
MyD88-dependent toll-like receptor signaling pathway Hs biological process
heart morphogenesis Hs biological process
catalytic activity Hs molecular function
protein serine/threonine phosphatase activity Hs molecular function
protein binding Hs molecular function
cytosol Hs cellular component
protein dephosphorylation Hs biological process
transforming growth factor beta receptor signaling pathway Hs biological process
I-kappaB kinase/NF-kappaB signaling Hs biological process
JNK cascade Hs biological process
enzyme activator activity Hs molecular function
endosome membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
protein deubiquitination Hs biological process
nuclear speck Hs cellular component
kinase activator activity Hs molecular function
lung development Hs biological process
aorta development Hs biological process
Fc-epsilon receptor signaling pathway Hs biological process
positive regulation of MAP kinase activity Hs biological process
mitogen-activated protein kinase p38 binding Hs molecular function
positive regulation of NF-kappaB transcription factor activity Hs biological process
coronary vasculature development Hs biological process
interleukin-1-mediated signaling pathway Hs biological process

GO (Blast)

19 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
catalytic activity Hs molecular function 332 1.14e-108
phosphoprotein phosphatase activity Hs molecular function 62.8 1.52e-10
protein serine/threonine phosphatase activity Hs molecular function 332 1.14e-108
protein binding Hs molecular function 332 1.14e-108
nucleus Hs cellular component 62.8 1.52e-10
nucleoplasm Hs cellular component 62.8 1.52e-10
cytoplasm Hs cellular component 62.8 1.52e-10
mitochondrion Hs cellular component 62.0 2.31e-10
mitochondrial matrix Hs cellular component 62.0 2.31e-10
cytosol Hs cellular component 332 1.14e-108
enzyme activator activity Hs molecular function 332 1.14e-108
endosome membrane Hs cellular component 332 1.14e-108
kinase activity Hs molecular function 332 1.14e-108
nuclear speck Hs cellular component 332 1.14e-108
hydrolase activity Hs molecular function 62.8 1.52e-10
kinase activator activity Hs molecular function 332 1.14e-108
cation binding Hs molecular function 62.8 1.52e-10
metal ion binding Hs molecular function 62.8 1.52e-10
mitogen-activated protein kinase p38 binding Hs molecular function 332 1.14e-108

GO (InterProScan)

3 results

GO Term Analysis Type e-value
catalytic activity CDD molecular function 4.98658E-43
protein serine/threonine phosphatase activity PANTHER molecular function 1.5E-135
protein dephosphorylation PANTHER biological process 1.5E-135