Gene Card
Best human hits
FRK; FYN; SRC
Unique Gene ID
Cirobu.g00012925
Gene Model ID
KH2012:KH.L65.19
Location
KhL65:157683..165141
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000005770 |
NCBI Reference Sequence | XM_002123599.3 |
cieg005e09
Plate: R1CiGC16o19
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Tyr_kinase_cat_dom | SMART | Tyrosine-protein kinase, catalytic domain |
SH3_domain | SMART | SH3 domain |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Tyr_kinase_AS | ProSitePatterns | Tyrosine-protein kinase, active site |
SH2 | PRINTS | SH2 domain |
SH3_domain | Pfam | SH3 domain |
SH2_dom_sf | Gene3D | SH2 domain superfamily |
Ser-Thr/Tyr_kinase_cat_dom | PRINTS | Serine-threonine/tyrosine-protein kinase, catalytic domain |
SH2 | Pfam | SH2 domain |
SH2 | SMART | SH2 domain |
Ser-Thr/Tyr_kinase_cat_dom | Pfam | Serine-threonine/tyrosine-protein kinase, catalytic domain |
SH3_domain | PRINTS | SH3 domain |
SH3-like_dom_sf | SUPERFAMILY | SH3-like domain superfamily |
SH2_dom_sf | SUPERFAMILY | SH2 domain superfamily |
SH2 | ProSiteProfiles | SH2 domain |
SH3_domain | ProSiteProfiles | SH3 domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Blast | molecular function |
protein kinase activity | Blast | molecular function |
signal transducer activity | Blast | molecular function |
receptor binding | Blast | molecular function |
integrin binding | Blast | molecular function |
protein binding | Blast | molecular function |
ATP binding | Blast | molecular function |
extracellular region | Blast | cellular component |
intracellular | Blast | cellular component |
nucleus | Blast | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Blast | cellular component |
mitochondrion | Blast | cellular component |
mitochondrial inner membrane | Blast | cellular component |
lysosome | Blast | cellular component |
endosome | Blast | cellular component |
cytosol | Blast | cellular component |
cytoskeleton | Blast | cellular component |
plasma membrane | Blast | cellular component |
protein phosphorylation | InterProScan | biological process |
protein C-terminus binding | Blast | molecular function |
tubulin binding | Blast | molecular function |
membrane | Blast | cellular component |
kinase activity | Blast | molecular function |
transferase activity | Blast | molecular function |
enzyme binding | Blast | molecular function |
kinase binding | Blast | molecular function |
protein kinase binding | Blast | molecular function |
heme binding | Blast | molecular function |
ubiquitin protein ligase binding | Blast | molecular function |
identical protein binding | Blast | molecular function |
neuron projection | Blast | cellular component |
intracellular membrane-bounded organelle | Blast | cellular component |
membrane raft | Blast | cellular component |
metal ion binding | Blast | molecular function |
perinuclear region of cytoplasm | Blast | cellular component |
cell adhesion molecule binding | Blast | molecular function |
extracellular exosome | Blast | cellular component |
cell periphery | Blast | cellular component |
cytoskeletal part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
positive regulation of signal transduction | Blast | biological process |
molecular function regulator | Blast | molecular function |
macromolecular complex binding | Blast | molecular function |
plasma membrane region | Blast | cellular component |
organelle | Blast | cellular component |
postsynapse | Blast | cellular component |
neuron part | Blast | cellular component |
transcription factor binding | Blast | molecular function |
intracellular part | Blast | cellular component |
plasma membrane part | Blast | cellular component |
cell projection membrane | Blast | cellular component |
cell leading edge | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
vacuolar part | Blast | cellular component |
endomembrane system | Blast | cellular component |
intracellular organelle lumen | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
phosphotransferase activity, alcohol group as acceptor | Blast | molecular function |
organic substance metabolic process | Blast | biological process |
cytoskeletal protein binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 401 | 7.86e-137 |
G-protein coupled receptor binding | Hs | molecular function | 366 | 9.04e-123 |
podosome | Hs | cellular component | 371 | 1.03e-124 |
protein kinase activity | Hs | molecular function | 401 | 7.86e-137 |
protein tyrosine kinase activity | Hs | molecular function | 401 | 7.86e-137 |
non-membrane spanning protein tyrosine kinase activity | Hs | molecular function | 401 | 7.86e-137 |
signal transducer activity | Hs | molecular function | 366 | 9.04e-123 |
SH3/SH2 adaptor activity | Hs | molecular function | 371 | 1.03e-124 |
protein kinase C binding | Hs | molecular function | 371 | 1.03e-124 |
Ras guanyl-nucleotide exchange factor activity | Hs | molecular function | 366 | 9.04e-123 |
receptor binding | Hs | molecular function | 401 | 7.86e-137 |
insulin receptor binding | Hs | molecular function | 371 | 1.03e-124 |
integrin binding | Hs | molecular function | 371 | 1.03e-124 |
protein binding | Hs | molecular function | 401 | 7.86e-137 |
ATP binding | Hs | molecular function | 401 | 7.86e-137 |
extracellular region | Hs | cellular component | 401 | 7.86e-137 |
intracellular | Hs | cellular component | 401 | 7.86e-137 |
nucleus | Hs | cellular component | 401 | 7.86e-137 |
nucleoplasm | Hs | cellular component | 371 | 1.03e-124 |
cytoplasm | Hs | cellular component | 401 | 7.86e-137 |
mitochondrion | Hs | cellular component | 371 | 1.03e-124 |
mitochondrial inner membrane | Hs | cellular component | 371 | 1.03e-124 |
lysosome | Hs | cellular component | 371 | 1.03e-124 |
endosome | Hs | cellular component | 366 | 9.04e-123 |
late endosome | Hs | cellular component | 371 | 1.03e-124 |
cytosol | Hs | cellular component | 401 | 7.86e-137 |
cytoskeleton | Hs | cellular component | 371 | 1.03e-124 |
actin filament | Hs | cellular component | 371 | 1.03e-124 |
plasma membrane | Hs | cellular component | 401 | 7.86e-137 |
caveola | Hs | cellular component | 371 | 1.03e-124 |
protein C-terminus binding | Hs | molecular function | 371 | 1.03e-124 |
postsynaptic density | Hs | cellular component | 371 | 1.03e-124 |
tubulin binding | Hs | molecular function | 366 | 9.04e-123 |
membrane | Hs | cellular component | 371 | 1.03e-124 |
kinase activity | Hs | molecular function | 401 | 7.86e-137 |
transferase activity | Hs | molecular function | 401 | 7.86e-137 |
enzyme binding | Hs | molecular function | 371 | 1.03e-124 |
kinase binding | Hs | molecular function | 371 | 1.03e-124 |
protein kinase binding | Hs | molecular function | 371 | 1.03e-124 |
protein domain specific binding | Hs | molecular function | 371 | 1.03e-124 |
heme binding | Hs | molecular function | 371 | 1.03e-124 |
estrogen receptor binding | Hs | molecular function | 371 | 1.03e-124 |
dendrite | Hs | cellular component | 366 | 9.04e-123 |
extrinsic component of cytoplasmic side of plasma membrane | Hs | cellular component | 401 | 7.86e-137 |
ubiquitin protein ligase binding | Hs | molecular function | 371 | 1.03e-124 |
type 5 metabotropic glutamate receptor binding | Hs | molecular function | 366 | 9.04e-123 |
ruffle membrane | Hs | cellular component | 371 | 1.03e-124 |
azurophil granule lumen | Hs | cellular component | 401 | 7.86e-137 |
specific granule lumen | Hs | cellular component | 401 | 7.86e-137 |
SH2 domain binding | Hs | molecular function | 371 | 1.03e-124 |
T cell receptor binding | Hs | molecular function | 366 | 9.04e-123 |
CD4 receptor binding | Hs | molecular function | 366 | 9.04e-123 |
CD8 receptor binding | Hs | molecular function | 366 | 9.04e-123 |
identical protein binding | Hs | molecular function | 366 | 9.04e-123 |
neuron projection | Hs | cellular component | 371 | 1.03e-124 |
intracellular membrane-bounded organelle | Hs | cellular component | 366 | 9.04e-123 |
phosphatidylinositol 3-kinase binding | Hs | molecular function | 366 | 9.04e-123 |
ion channel binding | Hs | molecular function | 371 | 1.03e-124 |
membrane raft | Hs | cellular component | 366 | 9.04e-123 |
cadherin binding | Hs | molecular function | 371 | 1.03e-124 |
metal ion binding | Hs | molecular function | 366 | 9.04e-123 |
ephrin receptor binding | Hs | molecular function | 371 | 1.03e-124 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity | Hs | molecular function | 371 | 1.03e-124 |
tau protein binding | Hs | molecular function | 366 | 9.04e-123 |
perinuclear region of cytoplasm | Hs | cellular component | 371 | 1.03e-124 |
cell adhesion molecule binding | Hs | molecular function | 371 | 1.03e-124 |
phosphoprotein binding | Hs | molecular function | 371 | 1.03e-124 |
hormone receptor binding | Hs | molecular function | 371 | 1.03e-124 |
peptide hormone receptor binding | Hs | molecular function | 366 | 9.04e-123 |
extracellular exosome | Hs | cellular component | 401 | 7.86e-137 |
growth factor receptor binding | Hs | molecular function | 371 | 1.03e-124 |
connexin binding | Hs | molecular function | 371 | 1.03e-124 |
cell periphery | Hs | cellular component | 366 | 9.04e-123 |
scaffold protein binding | Hs | molecular function | 371 | 1.03e-124 |
disordered domain specific binding | Hs | molecular function | 366 | 9.04e-123 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 1.7E-96 |
protein tyrosine kinase activity | SMART | molecular function | 7.1E-135 |
protein binding | SUPERFAMILY | molecular function | 9.58E-13 |
ATP binding | ProSiteProfiles | molecular function | 42.746 |
protein phosphorylation | SMART | biological process | 7.1E-135 |