Aniseed - Gene card

Gene Card

Best human hits

MMP14; MMP2; MMP9

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00013077

Gene Model ID

KH2012:KH.L76.4

Location

KhL76:175441..184260

Transcript Models and Sequences

KH2012:KH.L76.4.v1.A.ND2-1
KH2012:KH.L76.4.v1.A.nonSL4-1
KH2012:KH.L76.4.v1.A.SL1-1
KH2012:KH.L76.4.v1.A.SL3-1
KH2012:KH.L76.4.v1.A.SL5-1

External Database Gene Card

External database links

2 results

Database	Gene ID
ENSEMBL	ENSCING00000005511
NCBI Reference Sequence	XM_009863535.2

Collections

Gateway full ORF

4 results

Gene collection 1 (N. Satoh)

2 results

ciad006f19

Plate: R1CiGC01h09

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

23 results

IPR Term	Analysis	Definition
FN_type2_dom	ProSiteProfiles	Fibronectin type II domain
Kringle-like	SUPERFAMILY	Kringle-like fold
72kDa_collagenase	PANTHER	72kDa type IV collagenase
Pept_M10A	PRINTS	Peptidase M10A
Hemopexin-like_repeat	ProSiteProfiles	Hemopexin-like repeats
M10A_MMP	CDD	Peptidase M10A, catalytic domain
FN_type2_dom	CDD	Fibronectin type II domain
FN_type2_sf	Gene3D	Fibronectin type II domain superfamily
FN_type2_dom	Pfam	Fibronectin type II domain
Hemopexin-like_repeat	SMART	Hemopexin-like repeats
Pept_M10A_Zn_BS	ProSitePatterns	Peptidase M10A, cysteine switch, zinc binding site
PGBD-like_sf	SUPERFAMILY	PGBD-like superfamily
Hemopexin-like_repeat	Pfam	Hemopexin-like repeats
FN_type2_dom	ProSitePatterns	Fibronectin type II domain
Hemopexin_CS	ProSitePatterns	Hemopexin, conserved site
FN_type2_dom	SMART	Fibronectin type II domain
Hemopexin-like_dom_sf	SUPERFAMILY	Hemopexin-like domain superfamily
MetalloPept_cat_dom_sf	Gene3D	Metallopeptidase, catalytic domain superfamily
PGBDSf	Gene3D	PGBD superfamily
Pept_M10_metallopeptidase	Pfam	Peptidase M10, metallopeptidase
Hemopexin-like_dom_sf	Gene3D	Hemopexin-like domain superfamily
Hemopexin-like_dom	CDD	Hemopexin-like domain
Peptidase_Metallo	SMART	Peptidase, metallopeptidase

GOSlim

86 results

GO Term	Annotation Origin	Type
angiogenesis	Orthology	biological process
response to hypoxia	Orthology	biological process
endopeptidase activity	Orthology	molecular function
metalloendopeptidase activity	Orthology	molecular function
serine-type endopeptidase activity	Orthology	molecular function
integrin binding	Blast	molecular function
protein binding	Orthology	molecular function
extracellular region	Orthology	cellular component
extracellular space	Orthology	cellular component
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
mitochondrion	Orthology	cellular component
cytosol	Blast	cellular component
plasma membrane	Orthology	cellular component
integral component of plasma membrane	Blast	cellular component
focal adhesion	Blast	cellular component
proteolysis	Orthology	biological process
response to oxidative stress	Orthology	biological process
peptidase activity	Orthology	molecular function
metallopeptidase activity	Orthology	molecular function
zinc ion binding	Orthology	molecular function
membrane	Orthology	cellular component
integral component of membrane	Blast	cellular component
cell migration	Orthology	biological process
hydrolase activity	Orthology	molecular function
cytokine-mediated signaling pathway	Orthology	biological process
extracellular matrix organization	Orthology	biological process
cytoplasmic vesicle	Orthology	cellular component
melanosome	Blast	cellular component
identical protein binding	Orthology	molecular function
positive regulation of apoptotic process	Orthology	biological process
negative regulation of apoptotic process	Orthology	biological process
metal ion binding	Orthology	molecular function
head development	Orthology	biological process
extracellular exosome	Orthology	cellular component
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
calcium ion binding	Orthology	molecular function
endoplasmic reticulum	Orthology	cellular component
endoplasmic reticulum membrane	Orthology	cellular component
cell surface	Orthology	cellular component
positive regulation of gene expression	Orthology	biological process
wound healing	Orthology	biological process
sequence-specific DNA binding	Orthology	molecular function
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
system development	Orthology	biological process
protein phosphorylation	Orthology	biological process
blood vessel development	Orthology	biological process
animal organ development	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
macromolecular complex binding	Orthology	molecular function
cytoplasmic part	Orthology	cellular component
organelle part	Orthology	cellular component
intracellular non-membrane-bounded organelle	Orthology	cellular component
immune system process	Orthology	biological process
cell differentiation	Orthology	biological process
catabolic process	Orthology	biological process
extracellular region part	Orthology	cellular component
cellular response to stress	Orthology	biological process
anatomical structure formation involved in morphogenesis	Orthology	biological process
multicellular organism development	Orthology	biological process
DNA binding	Orthology	molecular function
innate immune response	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
positive regulation of signal transduction	Orthology	biological process
cellular response to organic substance	Orthology	biological process
organelle organization	Orthology	biological process
intracellular organelle part	Orthology	cellular component
endomembrane system	Orthology	cellular component
intracellular organelle lumen	Orthology	cellular component
intracellular signal transduction	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process
transcription regulatory region DNA binding	Orthology	molecular function
macromolecular complex	Orthology	cellular component
intracellular protein transport	Orthology	biological process
establishment of protein localization to organelle	Orthology	biological process
developmental process	Orthology	biological process
anion binding	Orthology	molecular function
carbohydrate derivative binding	Orthology	molecular function
protein metabolic process	Orthology	biological process
defense response	Orthology	biological process
Golgi apparatus part	Blast	cellular component
positive regulation of hydrolase activity	Blast	biological process
enzyme binding	Blast	molecular function
enzyme activator activity	Blast	molecular function
endosome	Blast	cellular component
cytoskeleton	Blast	cellular component

GO (Orthology)

81 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
skeletal system development	Hs	biological process
ossification	Hs	biological process
angiogenesis	Hs	biological process
response to hypoxia	Hs	biological process
positive regulation of protein phosphorylation	Hs	biological process
blood vessel maturation	Hs	biological process
intramembranous ossification	Hs	biological process
endochondral ossification	Hs	biological process
endopeptidase activity	Hs	molecular function
metalloendopeptidase activity	Hs	molecular function
serine-type endopeptidase activity	Hs	molecular function
protein binding	Hs	molecular function
collagen binding	Hs	molecular function
extracellular region	Hs	cellular component
proteinaceous extracellular matrix	Hs	cellular component
extracellular space	Hs	cellular component
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
mitochondrion	Hs	cellular component
plasma membrane	Hs	cellular component
proteolysis	Hs	biological process
peptidase activity	Hs	molecular function
metallopeptidase activity	Hs	molecular function
zinc ion binding	Hs	molecular function
membrane	Hs	cellular component
hydrolase activity	Hs	molecular function
cytokine-mediated signaling pathway	Hs	biological process
sarcomere	Hs	cellular component
extracellular matrix organization	Hs	biological process
macrophage differentiation	Hs	biological process
positive regulation of cell migration	Hs	biological process
collagen catabolic process	Hs	biological process
extracellular matrix	Hs	cellular component
cellular response to reactive oxygen species	Hs	biological process
endodermal cell differentiation	Hs	biological process
identical protein binding	Hs	molecular function
positive regulation of apoptotic process	Hs	biological process
negative regulation of apoptotic process	Hs	biological process
positive regulation of DNA binding	Hs	biological process
positive regulation of innate immune response	Hs	biological process
positive regulation of epidermal growth factor receptor signaling pathway	Hs	biological process
metal ion binding	Hs	molecular function
ephrin receptor signaling pathway	Hs	biological process
skeletal system morphogenesis	Hs	biological process
leukocyte migration	Hs	biological process
face morphogenesis	Hs	biological process
extracellular exosome	Hs	cellular component
cellular response to amino acid stimulus	Hs	biological process
cellular response to cadmium ion	Hs	biological process
positive regulation of release of cytochrome c from mitochondria	Hs	biological process
tertiary granule lumen	Hs	cellular component
ficolin-1-rich granule lumen	Hs	cellular component
negative regulation of intrinsic apoptotic signaling pathway	Hs	biological process
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
core promoter binding	Hs	molecular function
calcium ion binding	Hs	molecular function
collagen trimer	Hs	cellular component
endoplasmic reticulum	Hs	cellular component
endoplasmic reticulum membrane	Hs	cellular component
protein import into nucleus	Hs	biological process
aging	Hs	biological process
heparin binding	Hs	molecular function
cell surface	Hs	cellular component
positive regulation of gene expression	Hs	biological process
viral process	Hs	biological process
protein catabolic process	Hs	biological process
bone mineralization	Hs	biological process
regulation of cell migration	Hs	biological process
response to nutrient levels	Hs	biological process
wound healing, spreading of epidermal cells	Hs	biological process
specific granule lumen	Hs	cellular component
wound healing	Hs	biological process
extrinsic component of endoplasmic reticulum membrane	Hs	cellular component
sequence-specific DNA binding	Hs	molecular function
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
regulation of defense response to virus by host	Hs	biological process
cartilage development	Hs	biological process
negative regulation of type I interferon-mediated signaling pathway	Hs	biological process
bone morphogenesis	Hs	biological process
cellular response to mechanical stimulus	Hs	biological process
cellular response to virus	Hs	biological process

GO (Blast)

36 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
endopeptidase activity	Hs	molecular function	486	4.53e-162
metalloendopeptidase activity	Hs	molecular function	607	0.0
serine-type endopeptidase activity	Hs	molecular function	607	0.0
integrin binding	Hs	molecular function	160	1.20e-41
protein binding	Hs	molecular function	607	0.0
collagen binding	Hs	molecular function	486	4.53e-162
extracellular region	Hs	cellular component	607	0.0
proteinaceous extracellular matrix	Hs	cellular component	607	0.0
extracellular space	Hs	cellular component	607	0.0
nucleus	Hs	cellular component	607	0.0
cytoplasm	Hs	cellular component	607	0.0
mitochondrion	Hs	cellular component	607	0.0
Golgi lumen	Hs	cellular component	160	1.20e-41
cytosol	Hs	cellular component	160	1.20e-41
plasma membrane	Hs	cellular component	607	0.0
integral component of plasma membrane	Hs	cellular component	160	1.20e-41
focal adhesion	Hs	cellular component	160	1.20e-41
peptidase activity	Hs	molecular function	607	0.0
metallopeptidase activity	Hs	molecular function	607	0.0
zinc ion binding	Hs	molecular function	607	0.0
membrane	Hs	cellular component	607	0.0
integral component of membrane	Hs	cellular component	160	1.20e-41
peptidase activator activity	Hs	molecular function	160	1.20e-41
hydrolase activity	Hs	molecular function	607	0.0
sarcomere	Hs	cellular component	607	0.0
extracellular matrix	Hs	cellular component	607	0.0
cytoplasmic vesicle	Hs	cellular component	160	1.20e-41
melanosome	Hs	cellular component	160	1.20e-41
identical protein binding	Hs	molecular function	486	4.53e-162
macropinosome	Hs	cellular component	160	1.20e-41
intermediate filament cytoskeleton	Hs	cellular component	160	1.20e-41
metal ion binding	Hs	molecular function	607	0.0
metalloaminopeptidase activity	Hs	molecular function	160	1.20e-41
extracellular exosome	Hs	cellular component	486	4.53e-162
tertiary granule lumen	Hs	cellular component	486	4.53e-162
ficolin-1-rich granule lumen	Hs	cellular component	486	4.53e-162

GO (InterProScan)

5 results

GO Term	Analysis	Type	e-value
metalloendopeptidase activity	PANTHER	molecular function	7.0E-240
proteolysis	PANTHER	biological process	7.0E-240
metallopeptidase activity	Gene3D	molecular function	1.9E-160
zinc ion binding	Pfam	molecular function	2.6E-54
extracellular matrix	Pfam	cellular component	2.6E-54