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GENE CARD

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Gene Card

Collections

Gene collection 1 (N. Satoh)

2 results

citb9j18

Plate: R1CiGC30c07

ciad008l24

Plate: R1CiGC01j10

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

13 results

IPR Term Analysis Definition
Ras-like_Gua-exchang_fac_N ProSiteProfiles Ras-like guanine nucleotide exchange factor, N-terminal
Ras_GEF_dom_sf SUPERFAMILY Ras guanine nucleotide exchange factor domain superfamily
Ubiquitin-like_domsf SUPERFAMILY Ubiquitin-like domain superfamily
Ras_G-nucl-exch_fac_CS ProSitePatterns Ras guanine-nucleotide exchange factor, conserved site
RASGEF_cat_dom SMART Ras guanine-nucleotide exchange factors catalytic domain
RASGEF_cat_dom CDD Ras guanine-nucleotide exchange factors catalytic domain
Ras-like_Gua-exchang_fac_N SMART Ras-like guanine nucleotide exchange factor, N-terminal
RA_dom ProSiteProfiles Ras-associating (RA) domain
RASGEF_cat_dom Pfam Ras guanine-nucleotide exchange factors catalytic domain
Ras-like_Gua-exchang_fac_N Pfam Ras-like guanine nucleotide exchange factor, N-terminal
RASGEF_cat_dom_sf Gene3D Ras guanine-nucleotide exchange factor catalytic domain superfamily
RASGEF_cat_dom ProSiteProfiles Ras guanine-nucleotide exchange factors catalytic domain
Ras-like_Gua-exchang_fac_N CDD Ras-like guanine nucleotide exchange factor, N-terminal

GOSlim

19 results

GO Term Annotation Origin Type
protein binding Orthology molecular function
intracellular Orthology cellular component
nucleus Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
brush border Orthology cellular component
signal transduction Orthology biological process
small GTPase mediated signal transduction Orthology biological process
GTPase regulator activity Orthology molecular function
positive regulation of GTPase activity Orthology biological process
regulation of catalytic activity Orthology biological process
regulation of molecular function Orthology biological process
enzyme binding Orthology molecular function
molecular function regulator Orthology molecular function
organic substance metabolic process Orthology biological process
negative regulation of apoptotic process Orthology biological process
intracellular signal transduction Orthology biological process
positive regulation of signal transduction Orthology biological process
regulation of signal transduction Orthology biological process

GO (Orthology)

23 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
guanyl-nucleotide exchange factor activity Hs molecular function
protein binding Hs molecular function
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
brush border Hs cellular component
signal transduction Hs biological process
small GTPase mediated signal transduction Hs biological process
Ras protein signal transduction Hs biological process
Ral guanyl-nucleotide exchange factor activity Hs molecular function
Ras GTPase binding Hs molecular function
regulation of lipid metabolic process Hs biological process
GTPase regulator activity Hs molecular function
small GTPase binding Hs molecular function
positive regulation of GTPase activity Hs biological process
regulation of catalytic activity Hs biological process
regulation of molecular function Hs biological process
Ras guanyl-nucleotide exchange factor activity Hs molecular function
Rho guanyl-nucleotide exchange factor activity Hs molecular function
negative regulation of cardiac muscle cell apoptotic process Hs biological process
positive regulation of phosphatidylinositol 3-kinase signaling Hs biological process
regulation of Ral protein signal transduction Hs biological process

GO (Blast)

11 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
guanyl-nucleotide exchange factor activity Hs molecular function 305 1.22e-89
protein binding Hs molecular function 305 1.22e-89
intracellular Hs cellular component 212 7.35e-57
nucleus Hs cellular component 212 7.35e-57
cytoplasm Hs cellular component 212 7.35e-57
cytosol Hs cellular component 305 1.22e-89
brush border Hs cellular component 212 7.35e-57
Ral guanyl-nucleotide exchange factor activity Hs molecular function 305 1.22e-89
Ras GTPase binding Hs molecular function 196 3.64e-52
GTPase regulator activity Hs molecular function 212 7.35e-57
small GTPase binding Hs molecular function 196 3.64e-52

GO (InterProScan)

3 results

GO Term Analysis Type e-value
guanyl-nucleotide exchange factor activity Gene3D molecular function 1.5E-77
signal transduction ProSiteProfiles biological process 8.989
small GTPase mediated signal transduction Gene3D biological process 1.5E-77