Gene Card
Best human hits
MAPK3; MAPK4; MAPK6
Unique Gene ID
Cirobu.g00014797
Gene Model ID
KH2012:KH.S606.2
Location
KhS606:5183..19550
Transcript Models and Sequences
KH2012:KH.S606.2.v1.A.ND2-1
KH2012:KH.S606.2.v2.A.SL1-1
KH2012:KH.S606.2.v2.A.SL3-1
KH2012:KH.S606.2.v2.A.SL4-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000001296 |
NCBI Reference Sequence | NM_001078522.1 |
cien102621
Plate: VES86_C09
cien174931
Plate: VES97_C08
cicl007p06
Plate: R1CiGC09o17
cieg009d07
Plate: R1CiGC16p18
cicl060g03
Plate: R1CiGC15o09
cicl016m16
Plate: R1CiGC10m20
n/a
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IPR Term | Analysis | Definition |
---|---|---|
Prot_kinase_dom | Pfam | Protein kinase domain |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
MAPK_ERK3/4 | PRINTS | Mitogen-activated protein (MAP) kinase, ERK3/4 |
Tyr_kinase_AS | ProSitePatterns | Tyrosine-protein kinase, active site |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
intracellular | Orthology | cellular component |
nucleus | Orthology | cellular component |
nuclear envelope | Blast | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Blast | cellular component |
early endosome | Blast | cellular component |
Golgi apparatus | Blast | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Orthology | cellular component |
plasma membrane | Blast | cellular component |
focal adhesion | Blast | cellular component |
protein phosphorylation | Orthology | biological process |
cell cycle | Orthology | biological process |
signal transduction | Orthology | biological process |
regulation of gene expression | Orthology | biological process |
membrane | Blast | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
transferase activity | Orthology | molecular function |
protein kinase binding | Orthology | molecular function |
intracellular signal transduction | Orthology | biological process |
identical protein binding | Blast | molecular function |
protein homodimerization activity | Orthology | molecular function |
protein heterodimerization activity | Orthology | molecular function |
extracellular exosome | Blast | cellular component |
cellular response to organic substance | Orthology | biological process |
neuron projection development | Orthology | biological process |
positive regulation of catalytic activity | Blast | biological process |
positive regulation of signal transduction | Blast | biological process |
endosome | Blast | cellular component |
membrane raft | Blast | cellular component |
plasma membrane region | Blast | cellular component |
enzyme binding | Blast | molecular function |
cell projection | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
MAPK cascade | Hs | biological process |
nucleotide binding | Hs | molecular function |
protein kinase activity | Hs | molecular function |
protein serine/threonine kinase activity | Hs | molecular function |
MAP kinase activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
intracellular | Hs | cellular component |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
protein phosphorylation | Hs | biological process |
cell cycle | Hs | biological process |
signal transduction | Hs | biological process |
regulation of gene expression | Hs | biological process |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
transferase activity | Hs | molecular function |
protein kinase binding | Hs | molecular function |
septin cytoskeleton | Hs | cellular component |
protein homodimerization activity | Hs | molecular function |
protein heterodimerization activity | Hs | molecular function |
positive regulation of dendritic spine development | Hs | biological process |
cellular response to organic substance | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 337 | 1.37e-103 |
phosphotyrosine residue binding | Hs | molecular function | 245 | 3.45e-73 |
protein kinase activity | Hs | molecular function | 337 | 1.37e-103 |
protein serine/threonine kinase activity | Hs | molecular function | 337 | 1.37e-103 |
MAP kinase activity | Hs | molecular function | 337 | 1.37e-103 |
MAP kinase kinase activity | Hs | molecular function | 245 | 3.45e-73 |
protein binding | Hs | molecular function | 337 | 1.37e-103 |
ATP binding | Hs | molecular function | 337 | 1.37e-103 |
intracellular | Hs | cellular component | 308 | 2.54e-94 |
nucleus | Hs | cellular component | 337 | 1.37e-103 |
nuclear envelope | Hs | cellular component | 245 | 3.45e-73 |
nucleoplasm | Hs | cellular component | 337 | 1.37e-103 |
cytoplasm | Hs | cellular component | 337 | 1.37e-103 |
mitochondrion | Hs | cellular component | 245 | 3.45e-73 |
early endosome | Hs | cellular component | 245 | 3.45e-73 |
late endosome | Hs | cellular component | 245 | 3.45e-73 |
Golgi apparatus | Hs | cellular component | 245 | 3.45e-73 |
cytosol | Hs | cellular component | 337 | 1.37e-103 |
cytoskeleton | Hs | cellular component | 245 | 3.45e-73 |
plasma membrane | Hs | cellular component | 245 | 3.45e-73 |
caveola | Hs | cellular component | 245 | 3.45e-73 |
focal adhesion | Hs | cellular component | 245 | 3.45e-73 |
membrane | Hs | cellular component | 245 | 3.45e-73 |
kinase activity | Hs | molecular function | 337 | 1.37e-103 |
transferase activity | Hs | molecular function | 337 | 1.37e-103 |
protein kinase binding | Hs | molecular function | 337 | 1.37e-103 |
phosphatase binding | Hs | molecular function | 245 | 3.45e-73 |
pseudopodium | Hs | cellular component | 245 | 3.45e-73 |
septin cytoskeleton | Hs | cellular component | 337 | 1.37e-103 |
identical protein binding | Hs | molecular function | 245 | 3.45e-73 |
protein homodimerization activity | Hs | molecular function | 308 | 2.54e-94 |
protein heterodimerization activity | Hs | molecular function | 337 | 1.37e-103 |
extracellular exosome | Hs | cellular component | 245 | 3.45e-73 |
scaffold protein binding | Hs | molecular function | 245 | 3.45e-73 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 2.1E-58 |
MAP kinase activity | PRINTS | molecular function | 2.8E-9 |
ATP binding | Pfam | molecular function | 2.1E-58 |
protein phosphorylation | Pfam | biological process | 2.1E-58 |