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GENE CARD

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Gene Card

Best human hits

ANKFY1; HGS; ZFYVE28

Species

C.savignyi

Unique Gene ID

Cisavi.g00000091

Gene Model ID

Cisavi.CG.ENS81.R0.1861033-1866825

Location

R0:1861032..1866825

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

13 results

IPR Term Analysis Definition
Znf_FYVE-rel ProSiteProfiles Zinc finger, FYVE-related
ENTH_VHS Gene3D ENTH/VHS
VHS_dom Pfam VHS domain
Znf_FYVE_PHD SUPERFAMILY Zinc finger, FYVE/PHD-type
Znf_FYVE Pfam FYVE zinc finger
VHS_dom ProSiteProfiles VHS domain
VHS_dom SMART VHS domain
Znf_FYVE SMART FYVE zinc finger
ENTH_VHS SUPERFAMILY ENTH/VHS
Znf_RING/FYVE/PHD Gene3D Zinc finger, RING/FYVE/PHD-type
Ubi-bd_Hrs_VPS27 PIRSF Ubiquitin binding protein, Hrs/VPS27
HRS_helical Pfam Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain
UIM_dom ProSiteProfiles Ubiquitin interacting motif

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

36 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
protein binding Hs molecular function
intracellular Hs cellular component
cytoplasm Hs cellular component
lysosome Hs cellular component
endosome Hs cellular component
early endosome Hs cellular component
cytosol Hs cellular component
protein targeting to lysosome Hs biological process
intracellular protein transport Hs biological process
signal transduction Hs biological process
negative regulation of cell proliferation Hs biological process
positive regulation of gene expression Hs biological process
protein transport Hs biological process
membrane Hs cellular component
endosomal transport Hs biological process
macroautophagy Hs biological process
kinase activity Hs molecular function
phosphorylation Hs biological process
negative regulation of angiogenesis Hs biological process
protein deubiquitination Hs biological process
protein domain specific binding Hs molecular function
negative regulation of vascular endothelial growth factor receptor signaling pathway Hs biological process
early endosome membrane Hs cellular component
multivesicular body membrane Hs cellular component
ESCRT-0 complex Hs cellular component
multivesicular body assembly Hs biological process
negative regulation of epidermal growth factor receptor signaling pathway Hs biological process
regulation of protein catabolic process Hs biological process
intracellular membrane-bounded organelle Hs cellular component
regulation of MAP kinase activity Hs biological process
ubiquitin-like protein ligase binding Hs molecular function
negative regulation of JAK-STAT cascade Hs biological process
metal ion binding Hs molecular function
membrane organization Hs biological process
extracellular exosome Hs cellular component
protein localization to membrane Hs biological process

GO (Blast)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
protein binding Hs molecular function 503 7.64e-172
intracellular Hs cellular component 503 7.64e-172
cytoplasm Hs cellular component 503 7.64e-172
lysosome Hs cellular component 503 7.64e-172
lysosomal membrane Hs cellular component 89.7 1.00e-18
endosome Hs cellular component 503 7.64e-172
early endosome Hs cellular component 503 7.64e-172
cytosol Hs cellular component 503 7.64e-172
endosome membrane Hs cellular component 89.7 1.00e-18
membrane Hs cellular component 503 7.64e-172
kinase activity Hs molecular function 503 7.64e-172
Rab GTPase binding Hs molecular function 89.7 1.00e-18
protein domain specific binding Hs molecular function 503 7.64e-172
retromer complex Hs cellular component 89.7 1.00e-18
early endosome membrane Hs cellular component 503 7.64e-172
phosphatidylinositol-3-phosphate binding Hs molecular function 82.0 2.33e-16
multivesicular body membrane Hs cellular component 503 7.64e-172
ESCRT-0 complex Hs cellular component 503 7.64e-172
intracellular membrane-bounded organelle Hs cellular component 503 7.64e-172
macropinosome Hs cellular component 89.7 1.00e-18
ubiquitin-like protein ligase binding Hs molecular function 503 7.64e-172
metal ion binding Hs molecular function 503 7.64e-172
extracellular exosome Hs cellular component 503 7.64e-172
phosphatidylinositol phosphate binding Hs molecular function 89.7 1.00e-18

GO (InterProScan)

2 results

GO Term Analysis Type e-value
intracellular protein transport Pfam biological process 1.0E-32
metal ion binding SMART molecular function 1.5E-30