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GENE CARD

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Gene Card

Best human hits

HSP90AA1; HSP90AB1; HSP90B1

Species

C.savignyi

Unique Gene ID

Cisavi.g00001068

Gene Model ID

Cisavi.CG.ENS81.R11.207906-212165

Location

R11:207905..212165

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

14 results

IPR Term Analysis Definition
Heat_shock_protein_90_CS ProSitePatterns Heat shock protein Hsp90, conserved site
Hsp90_fam Hamap Heat shock protein Hsp90 family
HATPase_C_sf SUPERFAMILY Histidine kinase/HSP90-like ATPase superfamily
Hsp90_fam PIRSF Heat shock protein Hsp90 family
HATPase_C SMART Histidine kinase/HSP90-like ATPase
Hsp90_fam PANTHER Heat shock protein Hsp90 family
HATPase_C CDD Histidine kinase/HSP90-like ATPase
HATPase_C Pfam Histidine kinase/HSP90-like ATPase
HSP90_C Gene3D HSP90, C-terminal domain
Hsp90_N PRINTS Heat shock protein Hsp90, N-terminal
Ribosomal_S5_D2-typ_fold SUPERFAMILY Ribosomal protein S5 domain 2-type fold
HATPase_C_sf Gene3D Histidine kinase/HSP90-like ATPase superfamily
HSP90_C SUPERFAMILY HSP90, C-terminal domain
Hsp90_fam Pfam Heat shock protein Hsp90 family

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

120 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
G2/M transition of mitotic cell cycle Hs biological process
nucleotide binding Hs molecular function
positive regulation of protein phosphorylation Hs biological process
UTP binding Hs molecular function
CTP binding Hs molecular function
RNA binding Hs molecular function
double-stranded RNA binding Hs molecular function
protein tyrosine kinase activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
GTP binding Hs molecular function
extracellular region Hs cellular component
intracellular Hs cellular component
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
lysosomal membrane Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
protein folding Hs biological process
xenobiotic metabolic process Hs biological process
mitochondrial transport Hs biological process
receptor-mediated endocytosis Hs biological process
response to stress Hs biological process
response to unfolded protein Hs biological process
telomere maintenance via telomerase Hs biological process
signal transduction Hs biological process
drug binding Hs molecular function
COP9 signalosome Hs cellular component
response to heat Hs biological process
response to cold Hs biological process
response to salt stress Hs biological process
cell surface Hs cellular component
response to organic substance Hs biological process
regulation of G2/M transition of mitotic cell cycle Hs biological process
membrane Hs cellular component
inclusion body Hs cellular component
basolateral plasma membrane Hs cellular component
apical plasma membrane Hs cellular component
ATPase activity Hs molecular function
sulfonylurea receptor binding Hs molecular function
peptidyl-tyrosine phosphorylation Hs biological process
cytokine-mediated signaling pathway Hs biological process
protein kinase regulator activity Hs molecular function
kinase binding Hs molecular function
protein kinase binding Hs molecular function
central nervous system neuron axonogenesis Hs biological process
MHC class II protein complex binding Hs molecular function
establishment of cell polarity Hs biological process
nitric-oxide synthase regulator activity Hs molecular function
positive regulation of transforming growth factor beta receptor signaling pathway Hs biological process
TPR domain binding Hs molecular function
heat shock protein binding Hs molecular function
regulation of protein ubiquitination Hs biological process
brush border membrane Hs cellular component
positive regulation of protein binding Hs biological process
negative regulation of proteasomal ubiquitin-dependent protein catabolic process Hs biological process
positive regulation of phosphoprotein phosphatase activity Hs biological process
dATP binding Hs molecular function
ruffle membrane Hs cellular component
macromolecular complex Hs cellular component
positive regulation of peptidyl-serine phosphorylation Hs biological process
positive regulation of protein import into nucleus, translocation Hs biological process
aryl hydrocarbon receptor complex Hs cellular component
secretory granule lumen Hs cellular component
protein refolding Hs biological process
response to cocaine Hs biological process
peptide binding Hs molecular function
melanosome Hs cellular component
response to drug Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
histone deacetylase binding Hs molecular function
ATP-dependent protein binding Hs molecular function
neuronal cell body Hs cellular component
negative regulation of apoptotic process Hs biological process
lysosomal lumen Hs cellular component
myelin sheath Hs cellular component
negative regulation of neuron apoptotic process Hs biological process
dendritic growth cone Hs cellular component
axonal growth cone Hs cellular component
ion channel binding Hs molecular function
protein import into mitochondrial outer membrane Hs biological process
cadherin binding Hs molecular function
positive regulation of nitric oxide biosynthetic process Hs biological process
positive regulation of cell differentiation Hs biological process
positive regulation of cell size Hs biological process
response to antibiotic Hs biological process
protein dimerization activity Hs molecular function
vascular endothelial growth factor receptor signaling pathway Hs biological process
tau protein binding Hs molecular function
perinuclear region of cytoplasm Hs cellular component
axon extension Hs biological process
protein stabilization Hs biological process
regulation of nitric-oxide synthase activity Hs biological process
GTPase binding Hs molecular function
unfolded protein binding Hs molecular function
chaperone-mediated protein complex assembly Hs biological process
positive regulation of protein kinase B signaling Hs biological process
regulation of interferon-gamma-mediated signaling pathway Hs biological process
regulation of type I interferon-mediated signaling pathway Hs biological process
extracellular exosome Hs cellular component
DNA polymerase binding Hs molecular function
negative regulation of cell cycle arrest Hs biological process
cellular response to organic cyclic compound Hs biological process
endocytic vesicle lumen Hs cellular component
positive regulation of protein serine/threonine kinase activity Hs biological process
scaffold protein binding Hs molecular function
supramolecular fiber organization Hs biological process
disordered domain specific binding Hs molecular function
negative regulation of transforming growth factor beta activation Hs biological process
positive regulation of cellular protein catabolic process Hs biological process
positive regulation of cyclin-dependent protein kinase activity Hs biological process
ficolin-1-rich granule lumen Hs cellular component
histone methyltransferase binding Hs molecular function
protein tyrosine kinase binding Hs molecular function
sperm head plasma membrane Hs cellular component
ooplasm Hs cellular component
positive regulation of protein localization to cell surface Hs biological process

GO (Blast)

78 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 1074 0.0
UTP binding Hs molecular function 1064 0.0
CTP binding Hs molecular function 1064 0.0
RNA binding Hs molecular function 1074 0.0
double-stranded RNA binding Hs molecular function 1064 0.0
protein tyrosine kinase activity Hs molecular function 1074 0.0
calcium ion binding Hs molecular function 610 0.0
protein binding Hs molecular function 1074 0.0
ATP binding Hs molecular function 1074 0.0
GTP binding Hs molecular function 1064 0.0
extracellular region Hs cellular component 1074 0.0
intracellular Hs cellular component 1074 0.0
nucleus Hs cellular component 1074 0.0
nucleoplasm Hs cellular component 1074 0.0
cytoplasm Hs cellular component 1074 0.0
mitochondrion Hs cellular component 1064 0.0
lysosomal membrane Hs cellular component 1064 0.0
endoplasmic reticulum Hs cellular component 610 0.0
endoplasmic reticulum lumen Hs cellular component 610 0.0
endoplasmic reticulum membrane Hs cellular component 610 0.0
cytosol Hs cellular component 1074 0.0
plasma membrane Hs cellular component 1074 0.0
focal adhesion Hs cellular component 610 0.0
drug binding Hs molecular function 1064 0.0
COP9 signalosome Hs cellular component 1064 0.0
cell surface Hs cellular component 1064 0.0
membrane Hs cellular component 1074 0.0
inclusion body Hs cellular component 1064 0.0
basolateral plasma membrane Hs cellular component 1064 0.0
apical plasma membrane Hs cellular component 1064 0.0
ATPase activity Hs molecular function 1074 0.0
sulfonylurea receptor binding Hs molecular function 1064 0.0
protein kinase regulator activity Hs molecular function 1064 0.0
kinase binding Hs molecular function 1064 0.0
protein kinase binding Hs molecular function 1064 0.0
protein phosphatase binding Hs molecular function 610 0.0
MHC class II protein complex binding Hs molecular function 1074 0.0
nitric-oxide synthase regulator activity Hs molecular function 1074 0.0
midbody Hs cellular component 610 0.0
TPR domain binding Hs molecular function 1074 0.0
extracellular matrix Hs cellular component 610 0.0
heat shock protein binding Hs molecular function 1064 0.0
brush border membrane Hs cellular component 1064 0.0
dATP binding Hs molecular function 1064 0.0
ruffle membrane Hs cellular component 1074 0.0
macromolecular complex Hs cellular component 1074 0.0
endoplasmic reticulum chaperone complex Hs cellular component 610 0.0
aryl hydrocarbon receptor complex Hs cellular component 1064 0.0
secretory granule lumen Hs cellular component 1074 0.0
peptide binding Hs molecular function 1064 0.0
melanosome Hs cellular component 1074 0.0
identical protein binding Hs molecular function 1074 0.0
protein homodimerization activity Hs molecular function 1074 0.0
histone deacetylase binding Hs molecular function 1074 0.0
ATP-dependent protein binding Hs molecular function 1064 0.0
neuronal cell body Hs cellular component 1074 0.0
lysosomal lumen Hs cellular component 1074 0.0
myelin sheath Hs cellular component 1074 0.0
dendritic growth cone Hs cellular component 1074 0.0
axonal growth cone Hs cellular component 1074 0.0
ion channel binding Hs molecular function 1064 0.0
cadherin binding Hs molecular function 1064 0.0
protein dimerization activity Hs molecular function 1064 0.0
tau protein binding Hs molecular function 1074 0.0
perinuclear region of cytoplasm Hs cellular component 1074 0.0
low-density lipoprotein particle receptor binding Hs molecular function 610 0.0
GTPase binding Hs molecular function 1074 0.0
unfolded protein binding Hs molecular function 1074 0.0
extracellular exosome Hs cellular component 1074 0.0
DNA polymerase binding Hs molecular function 1074 0.0
endocytic vesicle lumen Hs cellular component 1074 0.0
scaffold protein binding Hs molecular function 1074 0.0
disordered domain specific binding Hs molecular function 1074 0.0
ficolin-1-rich granule lumen Hs cellular component 1074 0.0
histone methyltransferase binding Hs molecular function 1064 0.0
protein tyrosine kinase binding Hs molecular function 1074 0.0
sperm head plasma membrane Hs cellular component 1064 0.0
ooplasm Hs cellular component 1064 0.0

GO (InterProScan)

4 results

GO Term Analysis Type e-value
ATP binding PANTHER molecular function 0.0
protein folding PANTHER biological process 0.0
response to stress PANTHER biological process 0.0
unfolded protein binding PANTHER molecular function 0.0