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GENE CARD

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Gene Card

Best human hits

PLCB1; PLCB2; PLCB3

Species

C.savignyi

Unique Gene ID

Cisavi.g00003263

Gene Model ID

Cisavi.CG.ENS81.R167.194940-217616

Location

R167:194939..217616

Transcript Models and Sequences

  Cisavi.CG.ENS81.R167.194940-217616.04145.t
Cisavi.CG.ENS81.R167.194940-217616.04146.t
Cisavi.CG.ENS81.R167.194940-217616.04147.t
Cisavi.CG.ENS81.R167.194940-217616.04148.t
Cisavi.CG.ENS81.R167.194940-217616.04149.t
Cisavi.CG.ENS81.R167.194940-217616.04150.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

18 results

IPR Term Analysis Definition
PI-PLC_fam PANTHER Phosphoinositide phospholipase C family
PLC-like_Pdiesterase_TIM-brl SUPERFAMILY PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
PLipase_C_PInositol-sp_X_dom ProSiteProfiles Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC_fam PRINTS Phosphoinositide phospholipase C family
PLC-like_Pdiesterase_TIM-brl Gene3D PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
PLipase_C_Pinositol-sp_Y ProSiteProfiles Phospholipase C, phosphatidylinositol-specific, Y domain
EF-hand-dom_pair SUPERFAMILY EF-hand domain pair
C2_dom ProSiteProfiles C2 domain
C2_domain_sf Gene3D C2 domain superfamily
PLipase_C_PInositol-sp_X_dom Pfam Phosphatidylinositol-specific phospholipase C, X domain
PLipase_C_Pinositol-sp_Y SMART Phospholipase C, phosphatidylinositol-specific, Y domain
PLipase_C_PInositol-sp_X_dom SMART Phosphatidylinositol-specific phospholipase C, X domain
PLC_EF-hand-like Pfam Phosphoinositide-specific phospholipase C, EF-hand-like domain
C2_dom SMART C2 domain
PLC-beta_PH CDD PLC-beta, PH domain
PLipase_C_Pinositol-sp_Y Pfam Phospholipase C, phosphatidylinositol-specific, Y domain
PLC-beta PIRSF Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta
PLC-beta2 PANTHER 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

57 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
G2/M transition of mitotic cell cycle Hs biological process
nuclear chromatin Hs cellular component
phosphatidylinositol phospholipase C activity Hs molecular function
phospholipase C activity Hs molecular function
signal transducer activity Hs molecular function
GTPase activator activity Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
calmodulin binding Hs molecular function
lamin binding Hs molecular function
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function
intracellular Hs cellular component
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
lipid metabolic process Hs biological process
phospholipid metabolic process Hs biological process
signal transduction Hs biological process
G-protein coupled receptor signaling pathway Hs biological process
activation of phospholipase C activity Hs biological process
G-protein coupled acetylcholine receptor signaling pathway Hs biological process
Wnt signaling pathway, calcium modulating pathway Hs biological process
brain development Hs biological process
memory Hs biological process
phosphoric diester hydrolase activity Hs molecular function
regulation of G-protein coupled receptor protein signaling pathway Hs biological process
membrane Hs cellular component
lipid catabolic process Hs biological process
nuclear speck Hs cellular component
hydrolase activity Hs molecular function
enzyme binding Hs molecular function
cerebral cortex development Hs biological process
nuclear membrane Hs cellular component
macromolecular complex Hs cellular component
intracellular signal transduction Hs biological process
positive regulation of embryonic development Hs biological process
protein homodimerization activity Hs molecular function
myelin sheath Hs cellular component
positive regulation of GTPase activity Hs biological process
cadherin binding Hs molecular function
fat cell differentiation Hs biological process
positive regulation of myoblast differentiation Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of JNK cascade Hs biological process
phosphatidylinositol metabolic process Hs biological process
metal ion binding Hs molecular function
insulin-like growth factor receptor signaling pathway Hs biological process
positive regulation of developmental growth Hs biological process
sensory perception of bitter taste Hs biological process
regulation of cell cycle Hs biological process
extracellular exosome Hs cellular component
interleukin-1-mediated signaling pathway Hs biological process
regulation of fertilization Hs biological process
positive regulation of G1/S transition of mitotic cell cycle Hs biological process
positive regulation of acrosome reaction Hs biological process

GO (Blast)

27 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nuclear chromatin Hs cellular component 734 0.0
phosphatidylinositol phospholipase C activity Hs molecular function 791 0.0
phospholipase C activity Hs molecular function 791 0.0
signal transducer activity Hs molecular function 791 0.0
GTPase activator activity Hs molecular function 734 0.0
calcium ion binding Hs molecular function 791 0.0
protein binding Hs molecular function 791 0.0
calmodulin binding Hs molecular function 791 0.0
lamin binding Hs molecular function 734 0.0
phosphatidylinositol-4,5-bisphosphate binding Hs molecular function 734 0.0
intracellular Hs cellular component 739 0.0
nucleus Hs cellular component 734 0.0
nucleoplasm Hs cellular component 791 0.0
cytoplasm Hs cellular component 739 0.0
cytosol Hs cellular component 791 0.0
phosphoric diester hydrolase activity Hs molecular function 791 0.0
membrane Hs cellular component 791 0.0
nuclear speck Hs cellular component 734 0.0
hydrolase activity Hs molecular function 791 0.0
enzyme binding Hs molecular function 734 0.0
nuclear membrane Hs cellular component 734 0.0
macromolecular complex Hs cellular component 791 0.0
protein homodimerization activity Hs molecular function 734 0.0
myelin sheath Hs cellular component 734 0.0
cadherin binding Hs molecular function 791 0.0
metal ion binding Hs molecular function 739 0.0
extracellular exosome Hs cellular component 734 0.0

GO (InterProScan)

7 results

GO Term Analysis Type e-value
phosphatidylinositol phospholipase C activity PIRSF molecular function 0.0
phospholipase C activity PANTHER molecular function 2.5E-226
calcium ion binding PIRSF molecular function 0.0
lipid metabolic process SUPERFAMILY biological process 7.48E-125
signal transduction SMART biological process 2.9E-65
phosphoric diester hydrolase activity SUPERFAMILY molecular function 7.48E-125
intracellular signal transduction PANTHER biological process 6.9E-302

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