Gene Card
Best human hits
IARS2; LARS; MARS2
Species
Unique Gene ID
Cisavi.g00003372
Gene Model ID
Cisavi.CG.ENS81.R17.1671186-1688777
Location
R17:1671185..1688777
Transcript Models and Sequences
Cisavi.CG.ENS81.R17.1671186-1688777.15583.t
Cisavi.CG.ENS81.R17.1671186-1688777.15584.t
Cisavi.CG.ENS81.R17.1671186-1688777.15585.t
Cisavi.CG.ENS81.R17.1671186-1688777.15586.t
Cisavi.CG.ENS81.R17.1671186-1688777.15587.t
Cisavi.CG.ENS81.R17.1671186-1688777.15588.t
Cisavi.CG.ENS81.R17.1671186-1688777.15589.t
Cisavi.CG.ENS81.R17.1671186-1688777.15590.t
Cisavi.CG.ENS81.R17.1671186-1688777.15591.t
n/a
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InterPro
9 results
| IPR Term | Analysis | Definition |
|---|---|---|
| M/V/L/I-tRNA-synth_anticd-bd | Pfam | Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding |
| Val/Leu/Ile-tRNA-synth_edit | SUPERFAMILY | Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain |
| aa-tRNA-synth_Ia | Pfam | Aminoacyl-tRNA synthetase, class Ia |
| Leu-tRNA-synth_Ia_arc/euk | TIGRFAM | Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic |
| Leu-tRNA-synth_Ia_arc/euk | PANTHER | Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic |
| tRNAsynth_Ia_anticodon-bd | SUPERFAMILY | Aminoacyl-tRNA synthetase, class Ia, anticodon-binding |
| Methionyl/Leucyl_tRNA_Synth | Pfam | Methionyl/Leucyl tRNA synthetase |
| Rossmann-like_a/b/a_fold | Gene3D | Rossmann-like alpha/beta/alpha sandwich fold |
| Val/Leu/Ile-tRNA-synth_edit | Gene3D | Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
30 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| nucleotide binding | Hs | molecular function |
| aminoacyl-tRNA editing activity | Hs | molecular function |
| aminoacyl-tRNA ligase activity | Hs | molecular function |
| glutamine-tRNA ligase activity | Hs | molecular function |
| leucine-tRNA ligase activity | Hs | molecular function |
| valine-tRNA ligase activity | Hs | molecular function |
| GTPase activator activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| ATP binding | Hs | molecular function |
| cytoplasm | Hs | cellular component |
| lysosome | Hs | cellular component |
| endoplasmic reticulum | Hs | cellular component |
| cytosol | Hs | cellular component |
| translation | Hs | biological process |
| tRNA aminoacylation for protein translation | Hs | biological process |
| glutaminyl-tRNA aminoacylation | Hs | biological process |
| leucyl-tRNA aminoacylation | Hs | biological process |
| valyl-tRNA aminoacylation | Hs | biological process |
| protein targeting to lysosome | Hs | biological process |
| regulation of cell size | Hs | biological process |
| negative regulation of autophagy | Hs | biological process |
| endomembrane system | Hs | cellular component |
| nuclear body | Hs | cellular component |
| ligase activity | Hs | molecular function |
| aminoacyl-tRNA synthetase multienzyme complex | Hs | cellular component |
| cellular response to amino acid starvation | Hs | biological process |
| positive regulation of GTPase activity | Hs | biological process |
| cellular response to amino acid stimulus | Hs | biological process |
| positive regulation of TORC1 signaling | Hs | biological process |
| cellular response to leucine starvation | Hs | biological process |
GO (Blast)
22 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| tRNA binding | Hs | molecular function | 62.4 | 1.37e-09 |
| nucleotide binding | Hs | molecular function | 1544 | 0.0 |
| aminoacyl-tRNA editing activity | Hs | molecular function | 1544 | 0.0 |
| aminoacyl-tRNA ligase activity | Hs | molecular function | 1544 | 0.0 |
| glutamine-tRNA ligase activity | Hs | molecular function | 1544 | 0.0 |
| isoleucine-tRNA ligase activity | Hs | molecular function | 62.4 | 1.37e-09 |
| leucine-tRNA ligase activity | Hs | molecular function | 1544 | 0.0 |
| methionine-tRNA ligase activity | Hs | molecular function | 47.4 | 5.07e-05 |
| valine-tRNA ligase activity | Hs | molecular function | 1544 | 0.0 |
| GTPase activator activity | Hs | molecular function | 1544 | 0.0 |
| protein binding | Hs | molecular function | 1544 | 0.0 |
| ATP binding | Hs | molecular function | 1544 | 0.0 |
| cytoplasm | Hs | cellular component | 1544 | 0.0 |
| mitochondrion | Hs | cellular component | 62.4 | 1.37e-09 |
| mitochondrial matrix | Hs | cellular component | 62.4 | 1.37e-09 |
| lysosome | Hs | cellular component | 1544 | 0.0 |
| endoplasmic reticulum | Hs | cellular component | 1544 | 0.0 |
| cytosol | Hs | cellular component | 1544 | 0.0 |
| endomembrane system | Hs | cellular component | 1544 | 0.0 |
| nuclear body | Hs | cellular component | 1544 | 0.0 |
| ligase activity | Hs | molecular function | 1544 | 0.0 |
| aminoacyl-tRNA synthetase multienzyme complex | Hs | cellular component | 1544 | 0.0 |
GO (InterProScan)
8 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| nucleotide binding | PANTHER | molecular function | 0.0 |
| aminoacyl-tRNA editing activity | Gene3D | molecular function | 4.8E-221 |
| aminoacyl-tRNA ligase activity | SUPERFAMILY | molecular function | 1.5E-23 |
| leucine-tRNA ligase activity | PANTHER | molecular function | 0.0 |
| ATP binding | PANTHER | molecular function | 0.0 |
| cytoplasm | PANTHER | cellular component | 0.0 |
| tRNA aminoacylation for protein translation | Gene3D | biological process | 4.8E-221 |
| leucyl-tRNA aminoacylation | PANTHER | biological process | 0.0 |
