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GENE CARD

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Gene Card

Best human hits

AGO1; AGO2; AGO3

Species

C.savignyi

Unique Gene ID

Cisavi.g00004618

Gene Model ID

Cisavi.CG.ENS81.R22.812237-819985

Location

R22:812236..819985

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

14 results

IPR Term Analysis Definition
ArgoL1 SMART Argonaute, linker 1 domain
Piwi SMART Piwi domain
ArgoL1 Pfam Argonaute, linker 1 domain
ArgoL2 Pfam Argonaute linker 2 domain
PAZ_dom ProSiteProfiles PAZ domain
PAZ_dom_sf SUPERFAMILY PAZ domain superfamily
Argonaute_Mid_dom Pfam Protein argonaute, Mid domain
Piwi ProSiteProfiles Piwi domain
Piwi Pfam Piwi domain
PAZ_dom SMART PAZ domain
Argonaute_N Pfam Protein argonaute, N-terminal
RNaseH_sf Gene3D Ribonuclease H superfamily
RNaseH-like_sf SUPERFAMILY Ribonuclease H-like superfamily
PAZ_dom Pfam PAZ domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

76 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
RNA 7-methylguanosine cap binding Hs molecular function
condensed nuclear chromosome Hs cellular component
P-body Hs cellular component
nuclear-transcribed mRNA catabolic process Hs biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II core binding Hs molecular function
core promoter binding Hs molecular function
nucleic acid binding Hs molecular function
RNA binding Hs molecular function
double-stranded RNA binding Hs molecular function
single-stranded RNA binding Hs molecular function
mRNA binding Hs molecular function
translation initiation factor activity Hs molecular function
nuclease activity Hs molecular function
endonuclease activity Hs molecular function
endoribonuclease activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
polysome Hs cellular component
mRNA cap binding complex Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
mRNA catabolic process Hs biological process
translation Hs biological process
translational initiation Hs biological process
regulation of translation Hs biological process
Wnt signaling pathway, calcium modulating pathway Hs biological process
protein C-terminus binding Hs molecular function
post-embryonic development Hs biological process
RNA secondary structure unwinding Hs biological process
miRNA metabolic process Hs biological process
positive regulation of gene expression Hs biological process
membrane Hs cellular component
RISC complex Hs cellular component
negative regulation of angiogenesis Hs biological process
hydrolase activity Hs molecular function
cell junction Hs cellular component
production of siRNA involved in RNA interference Hs biological process
dendrite Hs cellular component
intracellular ribonucleoprotein complex Hs cellular component
gene silencing by RNA Hs biological process
pre-miRNA processing Hs biological process
micro-ribonucleoprotein complex Hs cellular component
siRNA loading onto RISC involved in RNA interference Hs biological process
production of miRNAs involved in gene silencing by miRNA Hs biological process
siRNA binding Hs molecular function
miRNA binding Hs molecular function
miRNA mediated inhibition of translation Hs biological process
mRNA cleavage involved in gene silencing by miRNA Hs biological process
miRNA loading onto RISC involved in gene silencing by miRNA Hs biological process
cytoplasmic ribonucleoprotein granule Hs cellular component
transcription regulatory region DNA binding Hs molecular function
positive regulation of angiogenesis Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
negative regulation of translational initiation Hs biological process
metal ion binding Hs molecular function
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening Hs biological process
regulation of gene silencing by miRNA Hs biological process
extracellular exosome Hs cellular component
endoribonuclease activity, cleaving siRNA-paired mRNA Hs molecular function
RISC-loading complex Hs cellular component
regulation of stem cell proliferation Hs biological process
RNA phosphodiester bond hydrolysis, endonucleolytic Hs biological process
endoribonuclease activity, cleaving miRNA-paired mRNA Hs molecular function
mRNA cap binding Hs molecular function
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Hs biological process
positive regulation of trophoblast cell migration Hs biological process
synaptonemal complex assembly Hs biological process
male meiotic nuclear division Hs biological process
male gonad development Hs biological process
nuclear body Hs cellular component
regulation of cell morphogenesis Hs biological process
negative regulation of apoptotic process Hs biological process

GO (Blast)

40 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
RNA 7-methylguanosine cap binding Hs molecular function 1305 0.0
condensed nuclear chromosome Hs cellular component 1244 0.0
P-body Hs cellular component 1305 0.0
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 1267 0.0
RNA polymerase II core binding Hs molecular function 1305 0.0
core promoter binding Hs molecular function 1305 0.0
nucleic acid binding Hs molecular function 1305 0.0
RNA binding Hs molecular function 1305 0.0
double-stranded RNA binding Hs molecular function 1305 0.0
single-stranded RNA binding Hs molecular function 1305 0.0
mRNA binding Hs molecular function 1305 0.0
translation initiation factor activity Hs molecular function 1305 0.0
nuclease activity Hs molecular function 1305 0.0
endonuclease activity Hs molecular function 1305 0.0
endoribonuclease activity Hs molecular function 1305 0.0
protein binding Hs molecular function 1305 0.0
nucleus Hs cellular component 1305 0.0
nucleoplasm Hs cellular component 1305 0.0
cytoplasm Hs cellular component 1305 0.0
cytosol Hs cellular component 1305 0.0
polysome Hs cellular component 1305 0.0
mRNA cap binding complex Hs cellular component 1305 0.0
protein C-terminus binding Hs molecular function 1305 0.0
membrane Hs cellular component 1305 0.0
RISC complex Hs cellular component 1305 0.0
hydrolase activity Hs molecular function 1305 0.0
cell junction Hs cellular component 1305 0.0
dendrite Hs cellular component 1305 0.0
intracellular ribonucleoprotein complex Hs cellular component 1305 0.0
micro-ribonucleoprotein complex Hs cellular component 1305 0.0
siRNA binding Hs molecular function 1305 0.0
miRNA binding Hs molecular function 1305 0.0
cytoplasmic ribonucleoprotein granule Hs cellular component 1244 0.0
transcription regulatory region DNA binding Hs molecular function 1267 0.0
metal ion binding Hs molecular function 1305 0.0
extracellular exosome Hs cellular component 1305 0.0
endoribonuclease activity, cleaving siRNA-paired mRNA Hs molecular function 1305 0.0
RISC-loading complex Hs cellular component 1305 0.0
endoribonuclease activity, cleaving miRNA-paired mRNA Hs molecular function 1305 0.0
mRNA cap binding Hs molecular function 1305 0.0

GO (InterProScan)

2 results

GO Term Analysis Type e-value
nucleic acid binding SMART molecular function 1.5E-127
protein binding SUPERFAMILY molecular function 1.19E-61