Gene Card
Best human hits
PLA2G4A; PLA2G4E; PLA2G4F
Species
Unique Gene ID
Cisavi.g00007302
Gene Model ID
Cisavi.CG.ENS81.R4.837037-852625
Location
R4:837036..852625
Transcript Models and Sequences
Cisavi.CG.ENS81.R4.837037-852625.13234.t
Cisavi.CG.ENS81.R4.837037-852625.13235.t
Cisavi.CG.ENS81.R4.837037-852625.13236.t
Cisavi.CG.ENS81.R4.837037-852625.13237.t
Cisavi.CG.ENS81.R4.837037-852625.13238.t
Cisavi.CG.ENS81.R4.837037-852625.13239.t
Cisavi.CG.ENS81.R4.837037-852625.13240.t
Cisavi.CG.ENS81.R4.837037-852625.13241.t
Cisavi.CG.ENS81.R4.837037-852625.13242.t
n/a
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InterPro
8 results
| IPR Term | Analysis | Definition |
|---|---|---|
| LysoPLipase_cat_dom | SMART | Lysophospholipase, catalytic domain |
| LysoPLipase_cat_dom | Pfam | Lysophospholipase, catalytic domain |
| C2_dom | SMART | C2 domain |
| C2_domain_sf | Gene3D | C2 domain superfamily |
| C2_dom | ProSiteProfiles | C2 domain |
| LysoPLipase_cat_dom | ProSiteProfiles | Lysophospholipase, catalytic domain |
| Acyl_Trfase/lysoPLipase | SUPERFAMILY | Acyl transferase/acyl hydrolase/lysophospholipase |
| C2_dom | Pfam | C2 domain |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
30 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| phospholipase activity | Hs | molecular function |
| lysophospholipase activity | Hs | molecular function |
| phospholipase A2 activity | Hs | molecular function |
| calcium ion binding | Hs | molecular function |
| calcium-dependent phospholipid binding | Hs | molecular function |
| cytoplasm | Hs | cellular component |
| mitochondrial inner membrane | Hs | cellular component |
| endoplasmic reticulum | Hs | cellular component |
| endoplasmic reticulum membrane | Hs | cellular component |
| Golgi apparatus | Hs | cellular component |
| lipid droplet | Hs | cellular component |
| cytosol | Hs | cellular component |
| lipid metabolic process | Hs | biological process |
| phospholipid metabolic process | Hs | biological process |
| phosphatidic acid biosynthetic process | Hs | biological process |
| metabolic process | Hs | biological process |
| phosphatidylcholine 1-acylhydrolase activity | Hs | molecular function |
| phospholipid catabolic process | Hs | biological process |
| lipid catabolic process | Hs | biological process |
| hydrolase activity | Hs | molecular function |
| arachidonic acid metabolic process | Hs | biological process |
| cytoplasmic vesicle | Hs | cellular component |
| cardiolipin acyl-chain remodeling | Hs | biological process |
| regulation of cell proliferation | Hs | biological process |
| metal ion binding | Hs | molecular function |
| calcium-dependent phospholipase A2 activity | Hs | molecular function |
| arachidonic acid secretion | Hs | biological process |
| cellular response to antibiotic | Hs | biological process |
| phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) | Hs | molecular function |
| phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) | Hs | molecular function |
GO (Blast)
24 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| phospholipase activity | Hs | molecular function | 697 | 0.0 |
| lysophospholipase activity | Hs | molecular function | 697 | 0.0 |
| phospholipase A2 activity | Hs | molecular function | 697 | 0.0 |
| calcium ion binding | Hs | molecular function | 697 | 0.0 |
| calcium-dependent phospholipid binding | Hs | molecular function | 697 | 0.0 |
| cytoplasm | Hs | cellular component | 697 | 0.0 |
| mitochondrial inner membrane | Hs | cellular component | 697 | 0.0 |
| lysosome | Hs | cellular component | 276 | 3.30e-81 |
| lysosomal membrane | Hs | cellular component | 276 | 3.30e-81 |
| endoplasmic reticulum | Hs | cellular component | 697 | 0.0 |
| endoplasmic reticulum membrane | Hs | cellular component | 697 | 0.0 |
| Golgi apparatus | Hs | cellular component | 697 | 0.0 |
| lipid droplet | Hs | cellular component | 697 | 0.0 |
| cytosol | Hs | cellular component | 697 | 0.0 |
| phosphatidylcholine 1-acylhydrolase activity | Hs | molecular function | 697 | 0.0 |
| membrane | Hs | cellular component | 276 | 3.30e-81 |
| hydrolase activity | Hs | molecular function | 697 | 0.0 |
| cytoplasmic vesicle | Hs | cellular component | 697 | 0.0 |
| vesicle | Hs | cellular component | 276 | 3.30e-81 |
| ruffle membrane | Hs | cellular component | 276 | 3.30e-81 |
| metal ion binding | Hs | molecular function | 697 | 0.0 |
| calcium-dependent phospholipase A2 activity | Hs | molecular function | 697 | 0.0 |
| phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) | Hs | molecular function | 697 | 0.0 |
| phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) | Hs | molecular function | 697 | 0.0 |
GO (InterProScan)
3 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| phospholipase activity | Pfam | molecular function | 9.0E-42 |
| metabolic process | SUPERFAMILY | biological process | 2.27E-122 |
| phospholipid catabolic process | Pfam | biological process | 9.0E-42 |
