Gene Card
Best human hits
DES; GFAP; VIM
Species
Unique Gene ID
Cisavi.g00009497
Gene Model ID
Cisavi.CG.ENS81.R58.3067831-3077101
Location
R58:3067830..3077101
Transcript Models and Sequences
Cisavi.CG.ENS81.R58.3067831-3077101.17627.t
Cisavi.CG.ENS81.R58.3067831-3077101.17628.t
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
5 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Intermediate_filament_CS | ProSitePatterns | Intermediate filament protein, conserved site |
| IF | PANTHER | Intermediate filament protein |
| Keratin_I | PRINTS | Keratin, type I |
| IF | Pfam | Intermediate filament protein |
| IF | SMART | Intermediate filament protein |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
103 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| double-stranded RNA binding | Hs | molecular function |
| integrin binding | Hs | molecular function |
| structural molecule activity | Hs | molecular function |
| structural constituent of cytoskeleton | Hs | molecular function |
| structural constituent of eye lens | Hs | molecular function |
| protein binding | Hs | molecular function |
| intracellular | Hs | cellular component |
| nucleus | Hs | cellular component |
| cytoplasm | Hs | cellular component |
| lysosome | Hs | cellular component |
| peroxisome | Hs | cellular component |
| cytosol | Hs | cellular component |
| polysome | Hs | cellular component |
| cytoskeleton | Hs | cellular component |
| intermediate filament | Hs | cellular component |
| neurofilament | Hs | cellular component |
| plasma membrane | Hs | cellular component |
| cell-cell junction | Hs | cellular component |
| fascia adherens | Hs | cellular component |
| focal adhesion | Hs | cellular component |
| muscle contraction | Hs | biological process |
| cytoskeleton organization | Hs | biological process |
| regulation of heart contraction | Hs | biological process |
| protein C-terminus binding | Hs | molecular function |
| cytoskeletal protein binding | Hs | molecular function |
| response to wounding | Hs | biological process |
| positive regulation of gene expression | Hs | biological process |
| negative regulation of neuron projection development | Hs | biological process |
| astrocyte development | Hs | biological process |
| intercalated disc | Hs | cellular component |
| membrane | Hs | cellular component |
| viral process | Hs | biological process |
| cytokine-mediated signaling pathway | Hs | biological process |
| kinase binding | Hs | molecular function |
| protein domain specific binding | Hs | molecular function |
| Z disc | Hs | cellular component |
| extracellular matrix organization | Hs | biological process |
| intracellular ribonucleoprotein complex | Hs | cellular component |
| neuron projection regeneration | Hs | biological process |
| cell leading edge | Hs | cellular component |
| neuromuscular junction | Hs | cellular component |
| sarcolemma | Hs | cellular component |
| identical protein binding | Hs | molecular function |
| cell projection | Hs | cellular component |
| neuron projection | Hs | cellular component |
| myelin sheath | Hs | cellular component |
| contractile fiber | Hs | cellular component |
| regulation of mRNA stability | Hs | biological process |
| cell body | Hs | cellular component |
| intermediate filament organization | Hs | biological process |
| intermediate filament cytoskeleton | Hs | cellular component |
| phagocytic vesicle | Hs | cellular component |
| positive regulation of translation | Hs | biological process |
| positive regulation of glial cell proliferation | Hs | biological process |
| long-term synaptic potentiation | Hs | biological process |
| SMAD protein signal transduction | Hs | biological process |
| axon development | Hs | biological process |
| extracellular exosome | Hs | cellular component |
| cellular response to interferon-gamma | Hs | biological process |
| scaffold protein binding | Hs | molecular function |
| glial cell projection | Hs | cellular component |
| astrocyte projection | Hs | cellular component |
| astrocyte end-foot | Hs | cellular component |
| cardiac myofibril | Hs | cellular component |
| cytoplasmic side of lysosomal membrane | Hs | cellular component |
| keratin filament binding | Hs | molecular function |
| MAPK cascade | Hs | biological process |
| microtubule cytoskeleton organization | Hs | biological process |
| Ras guanyl-nucleotide exchange factor activity | Hs | molecular function |
| extracellular space | Hs | cellular component |
| nucleoplasm | Hs | cellular component |
| multicellular organism development | Hs | biological process |
| nervous system development | Hs | biological process |
| microtubule binding | Hs | molecular function |
| anterograde axonal transport | Hs | biological process |
| retrograde axonal transport | Hs | biological process |
| response to toxic substance | Hs | biological process |
| response to organic substance | Hs | biological process |
| axonal transport of mitochondrion | Hs | biological process |
| spinal cord development | Hs | biological process |
| cerebral cortex development | Hs | biological process |
| cell differentiation | Hs | biological process |
| axon | Hs | cellular component |
| growth cone | Hs | cellular component |
| protein binding, bridging | Hs | molecular function |
| nuclear membrane | Hs | cellular component |
| TSC1-TSC2 complex | Hs | cellular component |
| cytoplasmic ribonucleoprotein granule | Hs | cellular component |
| locomotion | Hs | biological process |
| phospholipase binding | Hs | molecular function |
| response to peptide hormone | Hs | biological process |
| negative regulation of neuron apoptotic process | Hs | biological process |
| type III intermediate filament | Hs | cellular component |
| intermediate filament cytoskeleton organization | Hs | biological process |
| protein heterodimerization activity | Hs | molecular function |
| neuron projection morphogenesis | Hs | biological process |
| positive regulation of axonogenesis | Hs | biological process |
| neuromuscular process controlling balance | Hs | biological process |
| protein polymerization | Hs | biological process |
| neurofilament cytoskeleton organization | Hs | biological process |
| regulation of molecular function | Hs | biological process |
| neurofibrillary tangle | Hs | cellular component |
| axon cytoplasm | Hs | cellular component |
GO (Blast)
47 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| double-stranded RNA binding | Hs | molecular function | 319 | 9.97e-104 |
| integrin binding | Hs | molecular function | 279 | 1.31e-88 |
| structural molecule activity | Hs | molecular function | 319 | 9.97e-104 |
| structural constituent of cytoskeleton | Hs | molecular function | 319 | 9.97e-104 |
| structural constituent of eye lens | Hs | molecular function | 319 | 9.97e-104 |
| protein binding | Hs | molecular function | 319 | 9.97e-104 |
| intracellular | Hs | cellular component | 279 | 1.31e-88 |
| nucleus | Hs | cellular component | 276 | 3.18e-87 |
| cytoplasm | Hs | cellular component | 319 | 9.97e-104 |
| lysosome | Hs | cellular component | 279 | 1.31e-88 |
| peroxisome | Hs | cellular component | 319 | 9.97e-104 |
| cytosol | Hs | cellular component | 319 | 9.97e-104 |
| polysome | Hs | cellular component | 319 | 9.97e-104 |
| cytoskeleton | Hs | cellular component | 319 | 9.97e-104 |
| intermediate filament | Hs | cellular component | 319 | 9.97e-104 |
| neurofilament | Hs | cellular component | 279 | 1.31e-88 |
| plasma membrane | Hs | cellular component | 319 | 9.97e-104 |
| cell-cell junction | Hs | cellular component | 276 | 3.18e-87 |
| fascia adherens | Hs | cellular component | 276 | 3.18e-87 |
| focal adhesion | Hs | cellular component | 319 | 9.97e-104 |
| protein C-terminus binding | Hs | molecular function | 319 | 9.97e-104 |
| cytoskeletal protein binding | Hs | molecular function | 276 | 3.18e-87 |
| intercalated disc | Hs | cellular component | 276 | 3.18e-87 |
| membrane | Hs | cellular component | 279 | 1.31e-88 |
| kinase binding | Hs | molecular function | 279 | 1.31e-88 |
| protein domain specific binding | Hs | molecular function | 319 | 9.97e-104 |
| Z disc | Hs | cellular component | 276 | 3.18e-87 |
| intracellular ribonucleoprotein complex | Hs | cellular component | 319 | 9.97e-104 |
| cell leading edge | Hs | cellular component | 319 | 9.97e-104 |
| neuromuscular junction | Hs | cellular component | 276 | 3.18e-87 |
| sarcolemma | Hs | cellular component | 276 | 3.18e-87 |
| identical protein binding | Hs | molecular function | 319 | 9.97e-104 |
| cell projection | Hs | cellular component | 319 | 9.97e-104 |
| neuron projection | Hs | cellular component | 319 | 9.97e-104 |
| myelin sheath | Hs | cellular component | 279 | 1.31e-88 |
| contractile fiber | Hs | cellular component | 276 | 3.18e-87 |
| cell body | Hs | cellular component | 279 | 1.31e-88 |
| intermediate filament cytoskeleton | Hs | cellular component | 279 | 1.31e-88 |
| phagocytic vesicle | Hs | cellular component | 319 | 9.97e-104 |
| extracellular exosome | Hs | cellular component | 319 | 9.97e-104 |
| scaffold protein binding | Hs | molecular function | 319 | 9.97e-104 |
| glial cell projection | Hs | cellular component | 279 | 1.31e-88 |
| astrocyte projection | Hs | cellular component | 279 | 1.31e-88 |
| astrocyte end-foot | Hs | cellular component | 279 | 1.31e-88 |
| cardiac myofibril | Hs | cellular component | 276 | 3.18e-87 |
| cytoplasmic side of lysosomal membrane | Hs | cellular component | 279 | 1.31e-88 |
| keratin filament binding | Hs | molecular function | 319 | 9.97e-104 |
GO (InterProScan)
2 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| structural molecule activity | PANTHER | molecular function | 7.2E-148 |
| intermediate filament | PANTHER | cellular component | 7.2E-148 |
