Gene Card
Best human hits
PRKACB; PRKG1; PRKG2
Species
Unique Gene ID
Cisavi.g00011099
Gene Model ID
Cisavi.CG.ENS81.R88.346571-373071
Location
R88:346570..373071
Transcript Models and Sequences
Cisavi.CG.ENS81.R88.346571-373071.09600.t
Cisavi.CG.ENS81.R88.346571-373071.09601.t
Cisavi.CG.ENS81.R88.346571-373071.09602.t
Cisavi.CG.ENS81.R88.346571-373071.09603.t
Cisavi.CG.ENS81.R88.346571-373071.09604.t
Cisavi.CG.ENS81.R88.346571-373071.09605.t
Cisavi.CG.ENS81.R88.346571-373071.09606.t
Cisavi.CG.ENS81.R88.346571-373071.09607.t
n/a
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Click here to see the tree inference method
InterPro
19 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
| cNMP-bd_CS | ProSitePatterns | Cyclic nucleotide-binding, conserved site |
| STKc_cGK | CDD | cGMP-dependent protein kinase, catalytic domain |
| Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
| Prot_kinase_dom | SMART | Protein kinase domain |
| cGMP_dep_kinase | PIRSF | cGMP-dependent kinase |
| cGMP_dep_kinase | PRINTS | cGMP-dependent kinase |
| cNMP-bd_dom | ProSiteProfiles | Cyclic nucleotide-binding domain |
| cNMP-bd_dom | SMART | Cyclic nucleotide-binding domain |
| RmlC-like_jellyroll | Gene3D | RmlC-like jelly roll fold |
| cNMP-bd-like | SUPERFAMILY | Cyclic nucleotide-binding-like |
| PKcGMP_CC | Pfam | cGMP-dependent protein kinase, N-terminal coiled-coil domain |
| AGC-kinase_C | ProSiteProfiles | AGC-kinase, C-terminal |
| cNMP-bd_dom | CDD | Cyclic nucleotide-binding domain |
| Prot_kinase_dom | Pfam | Protein kinase domain |
| cNMP-bd_dom | Pfam | Cyclic nucleotide-binding domain |
| Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
| AGC-kinase_C | SMART | AGC-kinase, C-terminal |
| Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
26 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| nucleotide binding | Hs | molecular function |
| neuron migration | Hs | biological process |
| catalytic activity | Hs | molecular function |
| protein kinase activity | Hs | molecular function |
| protein serine/threonine kinase activity | Hs | molecular function |
| cGMP-dependent protein kinase activity | Hs | molecular function |
| calcium channel regulator activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| ATP binding | Hs | molecular function |
| cytoplasm | Hs | cellular component |
| Golgi apparatus | Hs | cellular component |
| cytosol | Hs | cellular component |
| plasma membrane | Hs | cellular component |
| protein phosphorylation | Hs | biological process |
| signal transduction | Hs | biological process |
| metabolic process | Hs | biological process |
| kinase activity | Hs | molecular function |
| phosphorylation | Hs | biological process |
| dendrite development | Hs | biological process |
| transferase activity | Hs | molecular function |
| cGMP-mediated signaling | Hs | biological process |
| actin cytoskeleton organization | Hs | biological process |
| cGMP binding | Hs | molecular function |
| forebrain development | Hs | biological process |
| regulation of GTPase activity | Hs | biological process |
| negative regulation of smooth muscle contraction | Hs | biological process |
GO (Blast)
30 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 843 | 0.0 |
| magnesium ion binding | Hs | molecular function | 273 | 2.00e-84 |
| catalytic activity | Hs | molecular function | 843 | 0.0 |
| protein kinase activity | Hs | molecular function | 843 | 0.0 |
| protein serine/threonine kinase activity | Hs | molecular function | 843 | 0.0 |
| cAMP-dependent protein kinase activity | Hs | molecular function | 273 | 2.00e-84 |
| cGMP-dependent protein kinase activity | Hs | molecular function | 843 | 0.0 |
| calcium channel regulator activity | Hs | molecular function | 843 | 0.0 |
| protein binding | Hs | molecular function | 843 | 0.0 |
| ATP binding | Hs | molecular function | 843 | 0.0 |
| nucleus | Hs | cellular component | 273 | 2.00e-84 |
| nucleoplasm | Hs | cellular component | 273 | 2.00e-84 |
| cytoplasm | Hs | cellular component | 843 | 0.0 |
| Golgi apparatus | Hs | cellular component | 843 | 0.0 |
| centrosome | Hs | cellular component | 273 | 2.00e-84 |
| cytosol | Hs | cellular component | 843 | 0.0 |
| plasma membrane | Hs | cellular component | 843 | 0.0 |
| cAMP-dependent protein kinase complex | Hs | cellular component | 273 | 2.00e-84 |
| membrane | Hs | cellular component | 637 | 0.0 |
| kinase activity | Hs | molecular function | 843 | 0.0 |
| apical plasma membrane | Hs | cellular component | 637 | 0.0 |
| transferase activity | Hs | molecular function | 843 | 0.0 |
| cGMP binding | Hs | molecular function | 843 | 0.0 |
| ubiquitin protein ligase binding | Hs | molecular function | 273 | 2.00e-84 |
| nuclear membrane | Hs | cellular component | 637 | 0.0 |
| protein homodimerization activity | Hs | molecular function | 637 | 0.0 |
| intercellular bridge | Hs | cellular component | 273 | 2.00e-84 |
| perinuclear region of cytoplasm | Hs | cellular component | 273 | 2.00e-84 |
| extracellular exosome | Hs | cellular component | 273 | 2.00e-84 |
| ciliary base | Hs | cellular component | 273 | 2.00e-84 |
GO (InterProScan)
5 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein kinase activity | SMART | molecular function | 1.0E-88 |
| protein serine/threonine kinase activity | SMART | molecular function | 5.9E-6 |
| cGMP-dependent protein kinase activity | CDD | molecular function | 2.17583E-179 |
| ATP binding | SMART | molecular function | 4.8E-88 |
| protein phosphorylation | SMART | biological process | 1.0E-88 |
