Aniseed - Gene card

Gene 'Haaura.CG.MTP2014.S2...'

Gene Card

Best human hits

GCLC

Species

H.aurantium

Unique Gene ID

Haaura.g00009505

Gene Model ID

Haaura.CG.MTP2014.S2324.g09505

Location

S2324:342..7960

Transcript Models and Sequences

Haaura.CG.MTP2014.S2324.g09505.01.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

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Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term	Analysis	Definition
GCS	PANTHER	Glutamate-cysteine ligase catalytic subunit
GCS	Pfam	Glutamate-cysteine ligase catalytic subunit
Gln_synth/guanido_kin_cat_dom	SUPERFAMILY	Glutamine synthetase/guanido kinase, catalytic domain

GOSlim

No result

GO Term	Annotation Origin	Type

GO (Orthology)

38 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
nucleotide binding	Hs	molecular function
magnesium ion binding	Hs	molecular function
catalytic activity	Hs	molecular function
glutamate-cysteine ligase activity	Hs	molecular function
ATP binding	Hs	molecular function
cytosol	Hs	cellular component
cysteine metabolic process	Hs	biological process
glutamate metabolic process	Hs	biological process
glutathione metabolic process	Hs	biological process
glutathione biosynthetic process	Hs	biological process
response to oxidative stress	Hs	biological process
aging	Hs	biological process
response to nutrient	Hs	biological process
apoptotic mitochondrial changes	Hs	biological process
response to heat	Hs	biological process
response to xenobiotic stimulus	Hs	biological process
response to hormone	Hs	biological process
response to activity	Hs	biological process
glutamate binding	Hs	molecular function
ligase activity	Hs	molecular function
glutamate-cysteine ligase complex	Hs	cellular component
negative regulation of protein ubiquitination	Hs	biological process
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Hs	biological process
cellular response to insulin stimulus	Hs	biological process
negative regulation of apoptotic process	Hs	biological process
negative regulation of neuron apoptotic process	Hs	biological process
ADP binding	Hs	molecular function
cell redox homeostasis	Hs	biological process
negative regulation of transcription, DNA-templated	Hs	biological process
response to arsenic-containing substance	Hs	biological process
response to cadmium ion	Hs	biological process
protein heterodimerization activity	Hs	molecular function
coenzyme binding	Hs	molecular function
regulation of blood vessel size	Hs	biological process
regulation of mitochondrial depolarization	Hs	biological process
cellular response to mechanical stimulus	Hs	biological process
cellular response to glucose stimulus	Hs	biological process
negative regulation of extrinsic apoptotic signaling pathway	Hs	biological process

GO (Blast)

12 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score
nucleotide binding	Hs	molecular function	783
magnesium ion binding	Hs	molecular function	783
catalytic activity	Hs	molecular function	783
glutamate-cysteine ligase activity	Hs	molecular function	783
ATP binding	Hs	molecular function	783
cytosol	Hs	cellular component	783
glutamate binding	Hs	molecular function	783
ligase activity	Hs	molecular function	783
glutamate-cysteine ligase complex	Hs	cellular component	783
ADP binding	Hs	molecular function	783
protein heterodimerization activity	Hs	molecular function	783
coenzyme binding	Hs	molecular function	783

GO (InterProScan)

3 results

GO Term	Analysis	Type	e-value
catalytic activity	SUPERFAMILY	molecular function	9.71E-54
glutamate-cysteine ligase activity	PANTHER	molecular function	6.3E-267
glutathione biosynthetic process	PANTHER	biological process	6.3E-267