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Gene Card

Best human hits

CDK12; CDK13; CDK9

Species

H.roretzi

Unique Gene ID

Harore.g00001020

Gene Model ID

Harore.CG.MTP2014.S230.g01020

Location

S230:6278..8189

Transcript Models and Sequences

  Harore.CG.MTP2014.S230.g01020.01.t

External Database Gene Card

External database links

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term Analysis Definition
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Prot_kinase_dom Pfam Protein kinase domain
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site
Prot_kinase_dom SMART Protein kinase domain
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site

GOSlim

53 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
DNA binding Orthology molecular function
chromatin binding Orthology molecular function
RNA binding Orthology molecular function
protein kinase activity Orthology molecular function
protein serine/threonine kinase activity Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
extracellular region Blast cellular component
extracellular space Blast cellular component
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
Golgi apparatus Blast cellular component
cytosol Blast cellular component
DNA repair Orthology biological process
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
transcription from RNA polymerase II promoter Orthology biological process
transcription initiation from RNA polymerase II promoter Orthology biological process
mRNA processing Orthology biological process
protein phosphorylation Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
transcription factor binding Orthology molecular function
cell proliferation Orthology biological process
membrane Orthology cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
nuclear speck Blast cellular component
transferase activity Orthology molecular function
protein kinase binding Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
cell cycle Orthology biological process
molecular transducer activity Orthology molecular function
intracellular non-membrane-bounded organelle Orthology cellular component
nucleoplasm part Orthology cellular component
macromolecular complex Orthology cellular component
nuclear body Orthology cellular component
DNA replication Orthology biological process
organelle organization Orthology biological process
cytoplasmic part Orthology cellular component
regulation of transcription from RNA polymerase II promoter Orthology biological process
negative regulation of gene expression Orthology biological process
protein ubiquitination Orthology biological process
nucleolus Blast cellular component
intracellular part Blast cellular component
nuclear part Blast cellular component
intracellular organelle part Blast cellular component
cytoplasmic vesicle Blast cellular component
endomembrane system Blast cellular component
intracellular organelle lumen Blast cellular component

GO (Orthology)

48 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
transcription coactivator binding Hs molecular function
DNA binding Hs molecular function
chromatin binding Hs molecular function
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
cyclin-dependent protein serine/threonine kinase activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
chromosome Hs cellular component
cytoplasm Hs cellular component
DNA repair Hs biological process
regulation of DNA repair Hs biological process
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
transcription from RNA polymerase II promoter Hs biological process
transcription initiation from RNA polymerase II promoter Hs biological process
transcription elongation from RNA polymerase II promoter Hs biological process
protein phosphorylation Hs biological process
cellular response to DNA damage stimulus Hs biological process
transcription elongation factor complex Hs cellular component
cyclin/CDK positive transcription elongation factor complex Hs cellular component
transcription factor binding Hs molecular function
cell proliferation Hs biological process
RNA polymerase II carboxy-terminal domain kinase activity Hs molecular function
membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
PML body Hs cellular component
transferase activity Hs molecular function
snRNA binding Hs molecular function
protein kinase binding Hs molecular function
cyclin binding Hs molecular function
replication fork processing Hs biological process
positive regulation of histone phosphorylation Hs biological process
cytoplasmic ribonucleoprotein granule Hs cellular component
response to drug Hs biological process
snRNA transcription from RNA polymerase II promoter Hs biological process
transcription regulatory region DNA binding Hs molecular function
positive regulation of transcription from RNA polymerase II promoter Hs biological process
phosphorylation of RNA polymerase II C-terminal domain Hs biological process
negative regulation of cell cycle arrest Hs biological process
7SK snRNA binding Hs molecular function
negative regulation of mRNA polyadenylation Hs biological process
positive regulation of histone H2B ubiquitination Hs biological process

GO (Blast)

39 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 551 0.0
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 551 0.0
transcription coactivator binding Hs molecular function 551 0.0
fibrillar center Hs cellular component 299 2.93e-91
cyclin K-CDK12 complex Hs cellular component 299 2.93e-91
cyclin K-CDK13 complex Hs cellular component 297 1.45e-90
DNA binding Hs molecular function 551 0.0
chromatin binding Hs molecular function 551 0.0
RNA binding Hs molecular function 297 1.45e-90
protein kinase activity Hs molecular function 551 0.0
protein serine/threonine kinase activity Hs molecular function 551 0.0
cyclin-dependent protein serine/threonine kinase activity Hs molecular function 551 0.0
protein binding Hs molecular function 551 0.0
ATP binding Hs molecular function 551 0.0
extracellular region Hs cellular component 297 1.45e-90
extracellular space Hs cellular component 297 1.45e-90
nucleus Hs cellular component 551 0.0
nucleoplasm Hs cellular component 551 0.0
chromosome Hs cellular component 551 0.0
cytoplasm Hs cellular component 551 0.0
Golgi apparatus Hs cellular component 297 1.45e-90
cytosol Hs cellular component 297 1.45e-90
transcription elongation factor complex Hs cellular component 551 0.0
cyclin/CDK positive transcription elongation factor complex Hs cellular component 551 0.0
transcription factor binding Hs molecular function 551 0.0
RNA polymerase II carboxy-terminal domain kinase activity Hs molecular function 551 0.0
membrane Hs cellular component 551 0.0
kinase activity Hs molecular function 551 0.0
PML body Hs cellular component 551 0.0
nuclear speck Hs cellular component 299 2.93e-91
transferase activity Hs molecular function 551 0.0
snRNA binding Hs molecular function 551 0.0
protein kinase binding Hs molecular function 551 0.0
nuclear cyclin-dependent protein kinase holoenzyme complex Hs cellular component 299 2.93e-91
cyclin binding Hs molecular function 551 0.0
cytoplasmic ribonucleoprotein granule Hs cellular component 551 0.0
transcription regulatory region DNA binding Hs molecular function 551 0.0
7SK snRNA binding Hs molecular function 551 0.0
ficolin-1-rich granule lumen Hs cellular component 297 1.45e-90

GO (InterProScan)

3 results

GO Term Analysis Type e-value
protein kinase activity SMART molecular function 1.0E-90
ATP binding SMART molecular function 1.0E-90
protein phosphorylation SMART biological process 1.0E-90

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