Gene Card
Best human hits
ALDH1A1; ALDH4A1; ALDH8A1
Species
Unique Gene ID
Harore.g00002695
Gene Model ID
Harore.CG.MTP2014.S11.g02695
Location
S11:463322..470333
Transcript Models and Sequences
Harore.CG.MTP2014.S11.g02695.01.t
Harore.CG.MTP2014.S11.g02695.02.t
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Ald_DH_C | Gene3D | Aldehyde dehydrogenase, C-terminal |
P5CDH/ALDH4A1 | CDD | Delta-1-pyrroline-5-carboxylate dehydrogenase |
P5CDH/ALDH4A1 | TIGRFAM | Delta-1-pyrroline-5-carboxylate dehydrogenase |
Ald_DH_CS_CYS | ProSitePatterns | Aldehyde dehydrogenase, cysteine active site |
Ald_DH_N | Gene3D | Aldehyde dehydrogenase, N-terminal |
Aldehyde_DH_dom | Pfam | Aldehyde dehydrogenase domain |
Ald_DH/histidinol_DH | SUPERFAMILY | Aldehyde/histidinol dehydrogenase |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Blast | molecular function |
GTPase activator activity | Blast | molecular function |
intracellular | Blast | cellular component |
cytoplasm | Blast | cellular component |
mitochondrion | Orthology | cellular component |
mitochondrial matrix | Orthology | cellular component |
cytosol | Blast | cellular component |
metabolic process | Orthology | biological process |
identical protein binding | Orthology | molecular function |
oxidation-reduction process | Orthology | biological process |
extracellular exosome | Blast | cellular component |
catalytic activity | Orthology | molecular function |
cellular metabolic process | Orthology | biological process |
organic substance metabolic process | Orthology | biological process |
binding | Blast | molecular function |
coenzyme binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
1-pyrroline-5-carboxylate dehydrogenase activity | Hs | molecular function |
aldehyde dehydrogenase (NAD) activity | Hs | molecular function |
mitochondrion | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
proline metabolic process | Hs | biological process |
proline catabolic process | Hs | biological process |
metabolic process | Hs | biological process |
electron carrier activity | Hs | molecular function |
proline catabolic process to glutamate | Hs | biological process |
oxidoreductase activity | Hs | molecular function |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | Hs | molecular function |
electron transport chain | Hs | biological process |
identical protein binding | Hs | molecular function |
glyoxylate metabolic process | Hs | biological process |
oxidation-reduction process | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 144 | 2.31e-37 |
retinal dehydrogenase activity | Hs | molecular function | 144 | 2.31e-37 |
1-pyrroline-5-carboxylate dehydrogenase activity | Hs | molecular function | 748 | 0.0 |
aldehyde dehydrogenase (NAD) activity | Hs | molecular function | 748 | 0.0 |
GTPase activator activity | Hs | molecular function | 144 | 2.31e-37 |
androgen binding | Hs | molecular function | 144 | 2.31e-37 |
intracellular | Hs | cellular component | 139 | 2.29e-35 |
cytoplasm | Hs | cellular component | 144 | 2.31e-37 |
mitochondrion | Hs | cellular component | 748 | 0.0 |
mitochondrial matrix | Hs | cellular component | 748 | 0.0 |
cytosol | Hs | cellular component | 144 | 2.31e-37 |
electron carrier activity | Hs | molecular function | 748 | 0.0 |
oxidoreductase activity | Hs | molecular function | 748 | 0.0 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | Hs | molecular function | 748 | 0.0 |
benzaldehyde dehydrogenase (NAD+) activity | Hs | molecular function | 144 | 2.31e-37 |
identical protein binding | Hs | molecular function | 748 | 0.0 |
NAD binding | Hs | molecular function | 144 | 2.31e-37 |
extracellular exosome | Hs | cellular component | 144 | 2.31e-37 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
1-pyrroline-5-carboxylate dehydrogenase activity | CDD | molecular function | 0.0 |
metabolic process | Gene3D | biological process | 1.1E-210 |
proline catabolic process to glutamate | CDD | biological process | 0.0 |
oxidoreductase activity | Gene3D | molecular function | 1.1E-210 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | Gene3D | molecular function | 1.1E-210 |
oxidation-reduction process | Gene3D | biological process | 1.1E-210 |