Gene Card
Best human hits
DST; MACF1; SYNE1
Species
Unique Gene ID
Harore.g00003001
Gene Model ID
Harore.CG.MTP2014.S1752.g03001
Location
S1752:0..3195
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
3 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Spectrin_repeat | Pfam | Spectrin repeat |
| SYNE1 | PANTHER | Nesprin-1 |
| Spectrin/alpha-actinin | SMART | Spectrin/alpha-actinin |
GOSlim
57 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| RNA binding | Blast | molecular function |
| actin binding | Blast | molecular function |
| integrin binding | Blast | molecular function |
| calcium ion binding | Blast | molecular function |
| protein binding | Blast | molecular function |
| nucleus | Blast | cellular component |
| nuclear envelope | Blast | cellular component |
| nucleoplasm | Blast | cellular component |
| nucleolus | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| endoplasmic reticulum membrane | Blast | cellular component |
| Golgi apparatus | Blast | cellular component |
| cytosol | Blast | cellular component |
| cytoskeleton | Blast | cellular component |
| microtubule | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| focal adhesion | Blast | cellular component |
| microtubule binding | Blast | molecular function |
| protein C-terminus binding | Blast | molecular function |
| cytoskeletal protein binding | Blast | molecular function |
| microtubule cytoskeleton | Blast | cellular component |
| membrane | Blast | cellular component |
| integral component of membrane | Blast | cellular component |
| enzyme binding | Blast | molecular function |
| cell junction | Blast | cellular component |
| axon | Blast | cellular component |
| cell leading edge | Blast | cellular component |
| cytoplasmic vesicle | Blast | cellular component |
| nuclear membrane | Blast | cellular component |
| protein homodimerization activity | Blast | molecular function |
| cell projection | Blast | cellular component |
| postsynaptic membrane | Blast | cellular component |
| metal ion binding | Blast | molecular function |
| actin filament binding | Blast | molecular function |
| extracellular exosome | Blast | cellular component |
| cytoplasmic part | Blast | cellular component |
| intracellular non-membrane-bounded organelle | Blast | cellular component |
| macromolecular complex | Blast | cellular component |
| extracellular region part | Blast | cellular component |
| membrane part | Blast | cellular component |
| whole membrane | Blast | cellular component |
| nuclear outer membrane-endoplasmic reticulum membrane network | Blast | cellular component |
| bounding membrane of organelle | Blast | cellular component |
| cytoskeletal part | Blast | cellular component |
| cell periphery | Blast | cellular component |
| basolateral plasma membrane | Blast | cellular component |
| nucleoside-triphosphatase activity | Blast | molecular function |
| organelle part | Blast | cellular component |
| cell-substrate junction | Blast | cellular component |
| cell projection membrane | Blast | cellular component |
| intrinsic component of membrane | Blast | cellular component |
| cell adhesion molecule binding | Blast | molecular function |
| cell projection part | Blast | cellular component |
| organelle organization | InterProScan | biological process |
| cell | InterProScan | cellular component |
| cellular protein localization | InterProScan | biological process |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
56 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| P-body | Hs | cellular component | 144 | 5.84e-38 |
| RNA binding | Hs | molecular function | 144 | 5.84e-38 |
| actin binding | Hs | molecular function | 144 | 5.84e-38 |
| integrin binding | Hs | molecular function | 49.7 | 2.01e-06 |
| calcium ion binding | Hs | molecular function | 50.4 | 9.33e-07 |
| protein binding | Hs | molecular function | 144 | 5.84e-38 |
| lamin binding | Hs | molecular function | 144 | 5.84e-38 |
| basement membrane | Hs | cellular component | 49.7 | 2.01e-06 |
| nucleus | Hs | cellular component | 144 | 5.84e-38 |
| nuclear envelope | Hs | cellular component | 144 | 5.84e-38 |
| nuclear outer membrane | Hs | cellular component | 144 | 5.84e-38 |
| nucleoplasm | Hs | cellular component | 144 | 5.84e-38 |
| nucleolus | Hs | cellular component | 144 | 5.84e-38 |
| cytoplasm | Hs | cellular component | 144 | 5.84e-38 |
| endoplasmic reticulum | Hs | cellular component | 49.7 | 2.01e-06 |
| endoplasmic reticulum membrane | Hs | cellular component | 49.7 | 2.01e-06 |
| Golgi apparatus | Hs | cellular component | 144 | 5.84e-38 |
| cytosol | Hs | cellular component | 49.7 | 2.01e-06 |
| cytoskeleton | Hs | cellular component | 144 | 5.84e-38 |
| microtubule | Hs | cellular component | 50.4 | 9.33e-07 |
| intermediate filament | Hs | cellular component | 49.7 | 2.01e-06 |
| plasma membrane | Hs | cellular component | 50.4 | 9.33e-07 |
| focal adhesion | Hs | cellular component | 49.7 | 2.01e-06 |
| cell cortex | Hs | cellular component | 49.7 | 2.01e-06 |
| microtubule binding | Hs | molecular function | 50.4 | 9.33e-07 |
| protein C-terminus binding | Hs | molecular function | 49.7 | 2.01e-06 |
| cytoskeletal protein binding | Hs | molecular function | 49.7 | 2.01e-06 |
| basal plasma membrane | Hs | cellular component | 49.7 | 2.01e-06 |
| actin cytoskeleton | Hs | cellular component | 50.4 | 9.33e-07 |
| microtubule cytoskeleton | Hs | cellular component | 49.7 | 2.01e-06 |
| membrane | Hs | cellular component | 144 | 5.84e-38 |
| integral component of membrane | Hs | cellular component | 144 | 5.84e-38 |
| ATPase activity | Hs | molecular function | 50.4 | 9.33e-07 |
| enzyme binding | Hs | molecular function | 144 | 5.84e-38 |
| sarcomere | Hs | cellular component | 144 | 5.84e-38 |
| Z disc | Hs | cellular component | 49.7 | 2.01e-06 |
| cell junction | Hs | cellular component | 50.4 | 9.33e-07 |
| hemidesmosome | Hs | cellular component | 49.7 | 2.01e-06 |
| axon | Hs | cellular component | 49.7 | 2.01e-06 |
| cell leading edge | Hs | cellular component | 49.7 | 2.01e-06 |
| cytoplasmic vesicle | Hs | cellular component | 49.7 | 2.01e-06 |
| H zone | Hs | cellular component | 49.7 | 2.01e-06 |
| nuclear membrane | Hs | cellular component | 144 | 5.84e-38 |
| ruffle membrane | Hs | cellular component | 50.4 | 9.33e-07 |
| LINC complex | Hs | cellular component | 144 | 5.84e-38 |
| microtubule plus-end | Hs | cellular component | 49.7 | 2.01e-06 |
| protein homodimerization activity | Hs | molecular function | 144 | 5.84e-38 |
| cell projection | Hs | cellular component | 50.4 | 9.33e-07 |
| postsynaptic membrane | Hs | cellular component | 144 | 5.84e-38 |
| cadherin binding | Hs | molecular function | 50.4 | 9.33e-07 |
| metal ion binding | Hs | molecular function | 50.4 | 9.33e-07 |
| microtubule plus-end binding | Hs | molecular function | 49.7 | 2.01e-06 |
| microtubule minus-end binding | Hs | molecular function | 50.4 | 9.33e-07 |
| actin filament binding | Hs | molecular function | 144 | 5.84e-38 |
| extracellular exosome | Hs | cellular component | 49.7 | 2.01e-06 |
| axon cytoplasm | Hs | cellular component | 49.7 | 2.01e-06 |
GO (InterProScan)
5 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein binding | Pfam | molecular function | 1.0E-7 |
| nuclear envelope | PANTHER | cellular component | 1.4E-59 |
| LINC complex | PANTHER | cellular component | 1.4E-59 |
| actin filament binding | PANTHER | molecular function | 1.4E-59 |
| cytoskeletal anchoring at nuclear membrane | PANTHER | biological process | 1.4E-59 |
