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GENE CARD

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Gene Card

Best human hits

TRAF2; TRAF4; TRAF6

Species

H.roretzi

Unique Gene ID

Harore.g00003158

Gene Model ID

Harore.CG.MTP2014.S53.g03158

Location

S53:311974..335087

Transcript Models and Sequences

  Harore.CG.MTP2014.S53.g03158.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
Znf_RING/FYVE/PHD Gene3D Zinc finger, RING/FYVE/PHD-type
TNF_rcpt--assoc_TRAF PIRSF TNF receptor-associated factor TRAF
Znf_RING ProSiteProfiles Zinc finger, RING-type
MATH/TRAF_dom ProSiteProfiles MATH/TRAF domain
Znf_TRAF Pfam Zinc finger, TRAF-type
Znf_RING_CS ProSitePatterns Zinc finger, RING-type, conserved site
TRAF-like SUPERFAMILY TRAF-like
TRAF-like Gene3D TRAF-like
TRAF4 PANTHER TNF receptor-associated factor 4
MATH/TRAF_dom SMART MATH/TRAF domain
Znf_RING SMART Zinc finger, RING-type
Znf_TRAF ProSiteProfiles Zinc finger, TRAF-type

GOSlim

51 results

GO Term Annotation Origin Type
DNA binding Orthology molecular function
ubiquitin-protein transferase activity Blast molecular function
signal transducer activity Blast molecular function
receptor binding Orthology molecular function
protein binding Orthology molecular function
intracellular Orthology cellular component
nucleus Orthology cellular component
nucleoplasm Blast cellular component
cytoplasm Orthology cellular component
cytosol Blast cellular component
cytoskeleton Orthology cellular component
plasma membrane Orthology cellular component
apoptotic process Orthology biological process
signal transduction Orthology biological process
multicellular organism development Orthology biological process
zinc ion binding Orthology molecular function
membrane Orthology cellular component
transferase activity Blast molecular function
enzyme binding Orthology molecular function
protein kinase binding Orthology molecular function
cell junction Orthology cellular component
ubiquitin protein ligase binding Orthology molecular function
macromolecular complex Blast cellular component
identical protein binding Orthology molecular function
regulation of apoptotic process Orthology biological process
membrane raft Blast cellular component
metal ion binding Orthology molecular function
protein N-terminus binding Blast molecular function
perinuclear region of cytoplasm Orthology cellular component
positive regulation of catalytic activity Orthology biological process
enzyme regulator activity Orthology molecular function
protein kinase activity Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
intracellular signal transduction Orthology biological process
positive regulation of signal transduction Orthology biological process
cellular response to stress Orthology biological process
protein phosphorylation Orthology biological process
intracellular part Blast cellular component
intracellular non-membrane-bounded organelle Blast cellular component
cell periphery Blast cellular component
cytoplasmic part Blast cellular component
binding Blast molecular function
plasma membrane part Blast cellular component
intracellular organelle part Blast cellular component
whole membrane Blast cellular component
endosome Blast cellular component
bounding membrane of organelle Blast cellular component
vesicle Blast cellular component
organelle membrane Blast cellular component
integral component of plasma membrane Blast cellular component
endoplasmic reticulum membrane Blast cellular component

GO (Orthology)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
DNA binding Hs molecular function
tumor necrosis factor receptor binding Hs molecular function
protein binding Hs molecular function
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
cytoskeleton Hs cellular component
plasma membrane Hs cellular component
bicellular tight junction Hs cellular component
apoptotic process Hs biological process
signal transduction Hs biological process
activation of NF-kappaB-inducing kinase activity Hs biological process
multicellular organism development Hs biological process
zinc ion binding Hs molecular function
membrane Hs cellular component
protein kinase binding Hs molecular function
cell junction Hs cellular component
ubiquitin protein ligase binding Hs molecular function
thioesterase binding Hs molecular function
identical protein binding Hs molecular function
regulation of apoptotic process Hs biological process
positive regulation of protein kinase activity Hs biological process
positive regulation of JNK cascade Hs biological process
metal ion binding Hs molecular function
perinuclear region of cytoplasm Hs cellular component
WW domain binding Hs molecular function

GO (Blast)

48 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
ubiquitin ligase complex Hs cellular component 160 2.97e-43
DNA binding Hs molecular function 530 0.0
ubiquitin-protein transferase activity Hs molecular function 164 3.47e-44
signal transducer activity Hs molecular function 160 2.97e-43
receptor binding Hs molecular function 160 2.97e-43
tumor necrosis factor receptor binding Hs molecular function 530 0.0
CD40 receptor binding Hs molecular function 160 2.97e-43
protein binding Hs molecular function 530 0.0
intracellular Hs cellular component 530 0.0
nucleus Hs cellular component 530 0.0
nucleoplasm Hs cellular component 160 2.97e-43
cytoplasm Hs cellular component 530 0.0
lipid droplet Hs cellular component 164 3.47e-44
cytosol Hs cellular component 164 3.47e-44
cytoskeleton Hs cellular component 530 0.0
plasma membrane Hs cellular component 530 0.0
bicellular tight junction Hs cellular component 530 0.0
cell cortex Hs cellular component 164 3.47e-44
zinc ion binding Hs molecular function 530 0.0
lipid binding Hs molecular function 160 2.97e-43
cytoplasmic side of plasma membrane Hs cellular component 164 3.47e-44
endosome membrane Hs cellular component 164 3.47e-44
vesicle membrane Hs cellular component 160 2.97e-43
membrane Hs cellular component 530 0.0
transferase activity Hs molecular function 164 3.47e-44
enzyme binding Hs molecular function 160 2.97e-43
protein kinase binding Hs molecular function 530 0.0
protein phosphatase binding Hs molecular function 160 2.97e-43
cell junction Hs cellular component 530 0.0
mitogen-activated protein kinase kinase kinase binding Hs molecular function 164 3.47e-44
ubiquitin conjugating enzyme binding Hs molecular function 164 3.47e-44
ubiquitin protein ligase binding Hs molecular function 530 0.0
thioesterase binding Hs molecular function 530 0.0
macromolecular complex Hs cellular component 164 3.47e-44
CD40 receptor complex Hs cellular component 164 3.47e-44
identical protein binding Hs molecular function 530 0.0
histone deacetylase binding Hs molecular function 164 3.47e-44
protein kinase B binding Hs molecular function 164 3.47e-44
membrane raft Hs cellular component 160 2.97e-43
sphingolipid binding Hs molecular function 160 2.97e-43
metal ion binding Hs molecular function 530 0.0
protein N-terminus binding Hs molecular function 164 3.47e-44
perinuclear region of cytoplasm Hs cellular component 530 0.0
WW domain binding Hs molecular function 530 0.0
ubiquitin protein ligase activity Hs molecular function 164 3.47e-44
TRAF2-GSTP1 complex Hs cellular component 160 2.97e-43
AIP1-IRE1 complex Hs cellular component 160 2.97e-43
IRE1-TRAF2-ASK1 complex Hs cellular component 160 2.97e-43

GO (InterProScan)

6 results

GO Term Analysis Type e-value
protein binding Gene3D molecular function 1.4E-60
signal transduction PIRSF biological process 1.8E-66
activation of NF-kappaB-inducing kinase activity PANTHER biological process 1.7E-111
zinc ion binding PIRSF molecular function 1.8E-66
regulation of apoptotic process PIRSF biological process 1.8E-66
positive regulation of JNK cascade PANTHER biological process 1.7E-111