Gene Card
Best human hits
EARS2; EPRS; QARS
Species
Unique Gene ID
Harore.g00004113
Gene Model ID
Harore.CG.MTP2014.S110.g04113
Location
S110:194875..197465
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Rbsml_L25/Gln-tRNA_synth_N | Gene3D | Ribosomal protein L25/Gln-tRNA synthetase, N-terminal |
Gln-tRNA-synth | TIGRFAM | Glutamine-tRNA synthetase |
Glu/Gln-tRNA-synth | PRINTS | Glutamyl/glutaminyl-tRNA synthetase |
Ribosomal_L25/Gln-tRNA_synth | SUPERFAMILY | Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily |
Glu/Gln-tRNA-synth_Ib_cat-dom | Pfam | Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain |
Rossmann-like_a/b/a_fold | Gene3D | Rossmann-like alpha/beta/alpha sandwich fold |
Glu/Gln-tRNA-synth_Ib_codon-bd | Pfam | Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain |
Gln-tRNA-synth_Ib_RNA-bd_2 | Pfam | Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 |
aa-tRNA-synth_I_CS | ProSitePatterns | Aminoacyl-tRNA synthetase, class I, conserved site |
Gln-tRNA-synth_Ib_RNA-bd_N | Pfam | Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
RNA binding | Blast | molecular function |
catalytic activity | Blast | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
cytoplasm | Orthology | cellular component |
mitochondrion | Blast | cellular component |
mitochondrial matrix | Orthology | cellular component |
cytosol | Orthology | cellular component |
brain development | Orthology | biological process |
zinc ion binding | Blast | molecular function |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
ligase activity | Orthology | molecular function |
protein kinase binding | Orthology | molecular function |
macromolecular complex | Orthology | cellular component |
identical protein binding | Blast | molecular function |
protein homodimerization activity | Blast | molecular function |
negative regulation of transcription, DNA-templated | Orthology | biological process |
metal ion binding | Blast | molecular function |
enzyme regulator activity | Orthology | molecular function |
protein kinase activity | Orthology | molecular function |
RNA metabolic process | Orthology | biological process |
regulation of catalytic activity | Orthology | biological process |
intracellular part | Orthology | cellular component |
intracellular signal transduction | Orthology | biological process |
cellular response to stress | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
negative regulation of apoptotic process | Orthology | biological process |
enzyme binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
aminoacyl-tRNA ligase activity | Hs | molecular function |
glutamine-tRNA ligase activity | Hs | molecular function |
protein kinase inhibitor activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
cytosol | Hs | cellular component |
translation | Hs | biological process |
tRNA aminoacylation for protein translation | Hs | biological process |
glutaminyl-tRNA aminoacylation | Hs | biological process |
negative regulation of protein kinase activity | Hs | biological process |
brain development | Hs | biological process |
membrane | Hs | cellular component |
integral component of membrane | Hs | cellular component |
ligase activity | Hs | molecular function |
aminoacyl-tRNA synthetase multienzyme complex | Hs | cellular component |
protein kinase binding | Hs | molecular function |
negative regulation of stress-activated MAPK cascade | Hs | biological process |
macromolecular complex | Hs | cellular component |
tRNA aminoacylation | Hs | biological process |
negative regulation of transcription, DNA-templated | Hs | biological process |
negative regulation of apoptotic signaling pathway | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
tRNA binding | Hs | molecular function | 55.8 | 7.21e-08 |
nucleotide binding | Hs | molecular function | 1032 | 0.0 |
RNA binding | Hs | molecular function | 244 | 6.74e-68 |
catalytic activity | Hs | molecular function | 244 | 6.74e-68 |
aminoacyl-tRNA ligase activity | Hs | molecular function | 1032 | 0.0 |
glutamate-tRNA ligase activity | Hs | molecular function | 244 | 6.74e-68 |
glutamine-tRNA ligase activity | Hs | molecular function | 1032 | 0.0 |
proline-tRNA ligase activity | Hs | molecular function | 244 | 6.74e-68 |
protein kinase inhibitor activity | Hs | molecular function | 1032 | 0.0 |
protein binding | Hs | molecular function | 1032 | 0.0 |
ATP binding | Hs | molecular function | 1032 | 0.0 |
cytoplasm | Hs | cellular component | 1032 | 0.0 |
mitochondrion | Hs | cellular component | 55.8 | 7.21e-08 |
mitochondrial matrix | Hs | cellular component | 1032 | 0.0 |
cytosol | Hs | cellular component | 1032 | 0.0 |
zinc ion binding | Hs | molecular function | 244 | 6.74e-68 |
membrane | Hs | cellular component | 1032 | 0.0 |
integral component of membrane | Hs | cellular component | 1032 | 0.0 |
ligase activity | Hs | molecular function | 1032 | 0.0 |
aminoacyl-tRNA synthetase multienzyme complex | Hs | cellular component | 1032 | 0.0 |
protein kinase binding | Hs | molecular function | 1032 | 0.0 |
intracellular ribonucleoprotein complex | Hs | cellular component | 244 | 6.74e-68 |
macromolecular complex | Hs | cellular component | 1032 | 0.0 |
RNA stem-loop binding | Hs | molecular function | 244 | 6.74e-68 |
identical protein binding | Hs | molecular function | 244 | 6.74e-68 |
protein homodimerization activity | Hs | molecular function | 244 | 6.74e-68 |
metal ion binding | Hs | molecular function | 244 | 6.74e-68 |
glutamate-tRNA(Gln) ligase activity | Hs | molecular function | 55.8 | 7.21e-08 |
GTPase binding | Hs | molecular function | 244 | 6.74e-68 |
GAIT complex | Hs | cellular component | 244 | 6.74e-68 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
nucleotide binding | TIGRFAM | molecular function | 1.2E-179 |
aminoacyl-tRNA ligase activity | Pfam | molecular function | 4.2E-111 |
glutamine-tRNA ligase activity | TIGRFAM | molecular function | 1.2E-179 |
ATP binding | TIGRFAM | molecular function | 1.2E-179 |
cytoplasm | TIGRFAM | cellular component | 1.2E-179 |
translation | SUPERFAMILY | biological process | 1.1E-52 |
tRNA aminoacylation for protein translation | Pfam | biological process | 5.0E-50 |
glutaminyl-tRNA aminoacylation | TIGRFAM | biological process | 1.2E-179 |
tRNA aminoacylation | Pfam | biological process | 4.2E-111 |