Gene Card
Best human hits
AC011462.1; PDHA1; PDHA2
Species
Unique Gene ID
Harore.g00005258
Gene Model ID
Harore.CG.MTP2014.S145.g05258
Location
S145:61950..66364
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
DH_E1 | Pfam | Dehydrogenase, E1 component |
THDP-binding | SUPERFAMILY | Thiamin diphosphate-binding fold |
Pyrv_DH_E1_asu_subgrp-y | TIGRFAM | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y |
GO Term | Annotation Origin | Type |
---|---|---|
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleolus | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
mitochondrial matrix | Orthology | cellular component |
metabolic process | Orthology | biological process |
myelin sheath | Orthology | cellular component |
intracellular membrane-bounded organelle | Orthology | cellular component |
oxidation-reduction process | Orthology | biological process |
catalytic activity | Orthology | molecular function |
organic substance metabolic process | Orthology | biological process |
phosphate-containing compound metabolic process | Orthology | biological process |
amide biosynthetic process | Orthology | biological process |
cellular metabolic process | Orthology | biological process |
transferase activity | Orthology | molecular function |
cytoplasmic part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
pyruvate dehydrogenase activity | Hs | molecular function |
pyruvate dehydrogenase (acetyl-transferring) activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleolus | Hs | cellular component |
mitochondrion | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
carbohydrate metabolic process | Hs | biological process |
glucose metabolic process | Hs | biological process |
acetyl-CoA biosynthetic process from pyruvate | Hs | biological process |
pyruvate metabolic process | Hs | biological process |
tricarboxylic acid cycle | Hs | biological process |
metabolic process | Hs | biological process |
oxidoreductase activity | Hs | molecular function |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Hs | molecular function |
pyruvate dehydrogenase (NAD+) activity | Hs | molecular function |
myelin sheath | Hs | cellular component |
intracellular membrane-bounded organelle | Hs | cellular component |
pyruvate dehydrogenase complex | Hs | cellular component |
oxidation-reduction process | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
alpha-ketoacid dehydrogenase activity | Hs | molecular function | 118 | 2.45e-29 |
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity | Hs | molecular function | 118 | 2.45e-29 |
pyruvate dehydrogenase activity | Hs | molecular function | 459 | 2.77e-161 |
pyruvate dehydrogenase (acetyl-transferring) activity | Hs | molecular function | 459 | 2.77e-161 |
protein binding | Hs | molecular function | 459 | 2.77e-161 |
nucleus | Hs | cellular component | 459 | 2.77e-161 |
nucleolus | Hs | cellular component | 459 | 2.77e-161 |
mitochondrion | Hs | cellular component | 459 | 2.77e-161 |
mitochondrial matrix | Hs | cellular component | 459 | 2.77e-161 |
oxidoreductase activity | Hs | molecular function | 459 | 2.77e-161 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Hs | molecular function | 459 | 2.77e-161 |
pyruvate dehydrogenase (NAD+) activity | Hs | molecular function | 459 | 2.77e-161 |
myelin sheath | Hs | cellular component | 459 | 2.77e-161 |
intracellular membrane-bounded organelle | Hs | cellular component | 459 | 2.77e-161 |
pyruvate dehydrogenase complex | Hs | cellular component | 459 | 2.77e-161 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
pyruvate dehydrogenase (acetyl-transferring) activity | TIGRFAM | molecular function | 9.1E-125 |
acetyl-CoA biosynthetic process from pyruvate | TIGRFAM | biological process | 9.1E-125 |
metabolic process | Pfam | biological process | 1.8E-110 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Pfam | molecular function | 1.8E-110 |
intracellular membrane-bounded organelle | TIGRFAM | cellular component | 9.1E-125 |