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GENE CARD

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Gene Card

Best human hits

AC011462.1; PDHA1; PDHA2

Species

H.roretzi

Unique Gene ID

Harore.g00005258

Gene Model ID

Harore.CG.MTP2014.S145.g05258

Location

S145:61950..66364

Transcript Models and Sequences

  Harore.CG.MTP2014.S145.g05258.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term Analysis Definition
DH_E1 Pfam Dehydrogenase, E1 component
THDP-binding SUPERFAMILY Thiamin diphosphate-binding fold
Pyrv_DH_E1_asu_subgrp-y TIGRFAM Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y

GOSlim

17 results

GO Term Annotation Origin Type
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleolus Orthology cellular component
mitochondrion Orthology cellular component
mitochondrial matrix Orthology cellular component
metabolic process Orthology biological process
myelin sheath Orthology cellular component
intracellular membrane-bounded organelle Orthology cellular component
oxidation-reduction process Orthology biological process
catalytic activity Orthology molecular function
organic substance metabolic process Orthology biological process
phosphate-containing compound metabolic process Orthology biological process
amide biosynthetic process Orthology biological process
cellular metabolic process Orthology biological process
transferase activity Orthology molecular function
cytoplasmic part Orthology cellular component
macromolecular complex Orthology cellular component

GO (Orthology)

20 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
pyruvate dehydrogenase activity Hs molecular function
pyruvate dehydrogenase (acetyl-transferring) activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleolus Hs cellular component
mitochondrion Hs cellular component
mitochondrial matrix Hs cellular component
carbohydrate metabolic process Hs biological process
glucose metabolic process Hs biological process
acetyl-CoA biosynthetic process from pyruvate Hs biological process
pyruvate metabolic process Hs biological process
tricarboxylic acid cycle Hs biological process
metabolic process Hs biological process
oxidoreductase activity Hs molecular function
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Hs molecular function
pyruvate dehydrogenase (NAD+) activity Hs molecular function
myelin sheath Hs cellular component
intracellular membrane-bounded organelle Hs cellular component
pyruvate dehydrogenase complex Hs cellular component
oxidation-reduction process Hs biological process

GO (Blast)

15 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
alpha-ketoacid dehydrogenase activity Hs molecular function 118 2.45e-29
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity Hs molecular function 118 2.45e-29
pyruvate dehydrogenase activity Hs molecular function 459 2.77e-161
pyruvate dehydrogenase (acetyl-transferring) activity Hs molecular function 459 2.77e-161
protein binding Hs molecular function 459 2.77e-161
nucleus Hs cellular component 459 2.77e-161
nucleolus Hs cellular component 459 2.77e-161
mitochondrion Hs cellular component 459 2.77e-161
mitochondrial matrix Hs cellular component 459 2.77e-161
oxidoreductase activity Hs molecular function 459 2.77e-161
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Hs molecular function 459 2.77e-161
pyruvate dehydrogenase (NAD+) activity Hs molecular function 459 2.77e-161
myelin sheath Hs cellular component 459 2.77e-161
intracellular membrane-bounded organelle Hs cellular component 459 2.77e-161
pyruvate dehydrogenase complex Hs cellular component 459 2.77e-161

GO (InterProScan)

5 results

GO Term Analysis Type e-value
pyruvate dehydrogenase (acetyl-transferring) activity TIGRFAM molecular function 9.1E-125
acetyl-CoA biosynthetic process from pyruvate TIGRFAM biological process 9.1E-125
metabolic process Pfam biological process 1.8E-110
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Pfam molecular function 1.8E-110
intracellular membrane-bounded organelle TIGRFAM cellular component 9.1E-125