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GENE CARD

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Gene Card

Best human hits

DAB2IP; RASA1; RASAL2

Species

H.roretzi

Unique Gene ID

Harore.g00006283

Gene Model ID

Harore.CG.MTP2014.S15.g06283

Location

S15:361824..378547

Transcript Models and Sequences

  Harore.CG.MTP2014.S15.g06283.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

25 results

IPR Term Analysis Definition
C2_dom ProSiteProfiles C2 domain
C2_domain_sf Gene3D C2 domain superfamily
SH3-like_dom_sf SUPERFAMILY SH3-like domain superfamily
PH-like_dom_sf Gene3D PH-like domain superfamily
SH2 ProSiteProfiles SH2 domain
RasGAP_dom Pfam Ras GTPase-activating domain
SH2 PRINTS SH2 domain
SH3_domain ProSiteProfiles SH3 domain
RasGAP_SH3 CDD RasGAP, SH3 domain
RasGAP_dom SMART Ras GTPase-activating domain
SH2_dom_sf Gene3D SH2 domain superfamily
SH3_domain SMART SH3 domain
PH_domain SMART Pleckstrin homology domain
Rho_GTPase_activation_prot SUPERFAMILY Rho GTPase activation protein
PH_domain ProSiteProfiles Pleckstrin homology domain
PH_domain Pfam Pleckstrin homology domain
p120-RasGAP PANTHER Ras GTPase-activating protein 1
RasGAP_CS ProSitePatterns Ras GTPase-activating protein, conserved site
C2_dom SMART C2 domain
RasGAP_dom ProSiteProfiles Ras GTPase-activating domain
C2_dom Pfam C2 domain
SH2 Pfam SH2 domain
SH3_domain Pfam SH3 domain
SH2_dom_sf SUPERFAMILY SH2 domain superfamily
SH2 SMART SH2 domain

GOSlim

47 results

GO Term Annotation Origin Type
GTPase activity Orthology molecular function
GTPase activator activity Orthology molecular function
receptor binding Orthology molecular function
protein binding Orthology molecular function
cytoplasm Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
signal transduction Orthology biological process
membrane Blast cellular component
kinase binding Blast molecular function
protein kinase binding Blast molecular function
axon Blast cellular component
intracellular signal transduction Orthology biological process
identical protein binding Blast molecular function
protein homodimerization activity Blast molecular function
cell projection Orthology cellular component
neuronal cell body Blast cellular component
negative regulation of apoptotic process Orthology biological process
regulation of GTPase activity Orthology biological process
positive regulation of GTPase activity Orthology biological process
macromolecular complex binding Blast molecular function
blood vessel morphogenesis Orthology biological process
extracellular exosome Blast cellular component
protein phosphorylation Orthology biological process
membrane organization Orthology biological process
cell division Orthology biological process
cell differentiation Orthology biological process
plasma membrane region Orthology cellular component
cell leading edge Orthology cellular component
cell adhesion Orthology biological process
cell morphogenesis Orthology biological process
molecular function regulator Orthology molecular function
transmembrane transport Orthology biological process
monovalent inorganic cation transport Orthology biological process
metal ion transport Orthology biological process
organelle organization Orthology biological process
intrinsic component of plasma membrane Orthology cellular component
small GTPase mediated signal transduction Orthology biological process
negative regulation of signal transduction Orthology biological process
cell surface receptor signaling pathway Orthology biological process
enzyme binding Orthology molecular function
cytoplasmic vesicle Blast cellular component
anion binding Blast molecular function
plasma membrane part Blast cellular component
positive regulation of signal transduction Blast biological process
cell adhesion molecule binding Blast molecular function
macromolecular complex Blast cellular component

GO (Orthology)

27 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
MAPK cascade Hs biological process
mitotic cytokinesis Hs biological process
vasculogenesis Hs biological process
ruffle Hs cellular component
phosphotyrosine residue binding Hs molecular function
GTPase activity Hs molecular function
GTPase activator activity Hs molecular function
receptor binding Hs molecular function
protein binding Hs molecular function
cytoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
negative regulation of cell adhesion Hs biological process
signal transduction Hs biological process
regulation of cell shape Hs biological process
potassium channel inhibitor activity Hs molecular function
regulation of actin filament polymerization Hs biological process
intrinsic component of the cytoplasmic side of the plasma membrane Hs cellular component
intracellular signal transduction Hs biological process
negative regulation of apoptotic process Hs biological process
regulation of GTPase activity Hs biological process
negative regulation of neuron apoptotic process Hs biological process
positive regulation of GTPase activity Hs biological process
negative regulation of Ras protein signal transduction Hs biological process
ephrin receptor signaling pathway Hs biological process
blood vessel morphogenesis Hs biological process
GTPase binding Hs molecular function

GO (Blast)

42 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
ruffle Hs cellular component 820 0.0
phosphotyrosine residue binding Hs molecular function 820 0.0
GTPase activity Hs molecular function 820 0.0
GTPase activator activity Hs molecular function 820 0.0
receptor binding Hs molecular function 820 0.0
death receptor binding Hs molecular function 189 4.73e-49
protein binding Hs molecular function 820 0.0
cytoplasm Hs cellular component 820 0.0
cytosol Hs cellular component 820 0.0
plasma membrane Hs cellular component 820 0.0
membrane Hs cellular component 189 4.73e-49
SH3 domain binding Hs molecular function 189 4.73e-49
potassium channel inhibitor activity Hs molecular function 820 0.0
kinase binding Hs molecular function 189 4.73e-49
protein kinase binding Hs molecular function 189 4.73e-49
endocytic vesicle Hs cellular component 189 4.73e-49
axon Hs cellular component 189 4.73e-49
dendrite Hs cellular component 189 4.73e-49
intrinsic component of the cytoplasmic side of the plasma membrane Hs cellular component 820 0.0
mitogen-activated protein kinase kinase binding Hs molecular function 189 4.73e-49
mitogen-activated protein kinase kinase kinase binding Hs molecular function 189 4.73e-49
phosphatidylinositol-3-phosphate binding Hs molecular function 189 4.73e-49
neuronal cell body membrane Hs cellular component 189 4.73e-49
signaling adaptor activity Hs molecular function 189 4.73e-49
phosphatidylinositol 3-kinase regulatory subunit binding Hs molecular function 189 4.73e-49
identical protein binding Hs molecular function 189 4.73e-49
protein homodimerization activity Hs molecular function 189 4.73e-49
cell projection Hs cellular component 189 4.73e-49
neuronal cell body Hs cellular component 189 4.73e-49
vascular endothelial growth factor receptor 2 binding Hs molecular function 189 4.73e-49
phosphatidylinositol 3-kinase binding Hs molecular function 189 4.73e-49
cerebellar mossy fiber Hs cellular component 189 4.73e-49
climbing fiber Hs cellular component 189 4.73e-49
macromolecular complex binding Hs molecular function 189 4.73e-49
cadherin binding Hs molecular function 189 4.73e-49
GTPase binding Hs molecular function 820 0.0
protein phosphatase 2A binding Hs molecular function 189 4.73e-49
extracellular exosome Hs cellular component 189 4.73e-49
phosphatidylinositol-4-phosphate binding Hs molecular function 189 4.73e-49
14-3-3 protein binding Hs molecular function 189 4.73e-49
parallel fiber Hs cellular component 189 4.73e-49
AIP1-IRE1 complex Hs cellular component 189 4.73e-49

GO (InterProScan)

6 results

GO Term Analysis Type e-value
GTPase activator activity PANTHER molecular function 0.0
protein binding SUPERFAMILY molecular function 4.2E-8
signal transduction SUPERFAMILY biological process 1.69E-69
regulation of GTPase activity SMART biological process 5.2E-94
positive regulation of GTPase activity PANTHER biological process 0.0
negative regulation of Ras protein signal transduction PANTHER biological process 0.0

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