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GENE CARD

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Gene Card

Best human hits

ARAF; KSR1; KSR2

Species

H.roretzi

Unique Gene ID

Harore.g00006934

Gene Model ID

Harore.CG.MTP2014.S326.g06934

Location

S326:45359..58097

Transcript Models and Sequences

  Harore.CG.MTP2014.S326.g06934.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term Analysis Definition
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Prot_kinase_dom SMART Protein kinase domain
KSR_SAM-like_dom Pfam Kinase suppressor of RAS, SAM-like domain
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain

GOSlim

30 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
protein kinase activity Orthology molecular function
protein serine/threonine kinase activity Orthology molecular function
signal transducer activity Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
intracellular Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Blast cellular component
endoplasmic reticulum Orthology cellular component
endoplasmic reticulum membrane Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
protein phosphorylation Orthology biological process
protein C-terminus binding Orthology molecular function
membrane Orthology cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
transferase activity Orthology molecular function
macromolecular complex Orthology cellular component
intracellular signal transduction Orthology biological process
cell projection Orthology cellular component
metal ion binding Orthology molecular function
kinase binding Orthology molecular function
positive regulation of signal transduction Orthology biological process
small GTPase mediated signal transduction Orthology biological process
protein kinase binding Orthology molecular function
cell projection membrane Orthology cellular component
cell leading edge Orthology cellular component
positive regulation of catalytic activity Blast biological process

GO (Orthology)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
MAPK cascade Hs biological process
nucleotide binding Hs molecular function
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
signal transducer activity Hs molecular function
MAP-kinase scaffold activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
intracellular Hs cellular component
cytoplasm Hs cellular component
endoplasmic reticulum Hs cellular component
endoplasmic reticulum membrane Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
protein phosphorylation Hs biological process
Ras protein signal transduction Hs biological process
protein C-terminus binding Hs molecular function
membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
transferase activity Hs molecular function
calcium-mediated signaling Hs biological process
cAMP-mediated signaling Hs biological process
mitogen-activated protein kinase kinase binding Hs molecular function
ruffle membrane Hs cellular component
macromolecular complex Hs cellular component
intracellular signal transduction Hs biological process
cell projection Hs cellular component
positive regulation of MAPK cascade Hs biological process
metal ion binding Hs molecular function
chaperone binding Hs molecular function
Hsp90 protein binding Hs molecular function
14-3-3 protein binding Hs molecular function

GO (Blast)

28 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 320 1.24e-93
protein kinase activity Hs molecular function 320 1.24e-93
protein serine/threonine kinase activity Hs molecular function 320 1.24e-93
MAP kinase kinase kinase activity Hs molecular function 172 7.72e-45
signal transducer activity Hs molecular function 320 1.24e-93
signal transducer activity, downstream of receptor Hs molecular function 172 7.72e-45
MAP-kinase scaffold activity Hs molecular function 297 3.28e-86
protein binding Hs molecular function 320 1.24e-93
ATP binding Hs molecular function 320 1.24e-93
intracellular Hs cellular component 320 1.24e-93
cytoplasm Hs cellular component 320 1.24e-93
mitochondrion Hs cellular component 172 7.72e-45
endoplasmic reticulum Hs cellular component 297 3.28e-86
endoplasmic reticulum membrane Hs cellular component 297 3.28e-86
cytosol Hs cellular component 320 1.24e-93
plasma membrane Hs cellular component 320 1.24e-93
protein C-terminus binding Hs molecular function 297 3.28e-86
membrane Hs cellular component 320 1.24e-93
kinase activity Hs molecular function 320 1.24e-93
transferase activity Hs molecular function 320 1.24e-93
mitogen-activated protein kinase kinase binding Hs molecular function 297 3.28e-86
ruffle membrane Hs cellular component 297 3.28e-86
macromolecular complex Hs cellular component 297 3.28e-86
cell projection Hs cellular component 297 3.28e-86
metal ion binding Hs molecular function 320 1.24e-93
chaperone binding Hs molecular function 297 3.28e-86
Hsp90 protein binding Hs molecular function 297 3.28e-86
14-3-3 protein binding Hs molecular function 297 3.28e-86

GO (InterProScan)

3 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 2.8E-49
ATP binding SMART molecular function 9.6E-38
protein phosphorylation Pfam biological process 2.8E-49