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Gene Card

Best human hits

RAPGEF1

Species

H.roretzi

Unique Gene ID

Harore.g00009612

Gene Model ID

Harore.CG.MTP2014.S219.g09612

Location

S219:2628..28830

Transcript Models and Sequences

  Harore.CG.MTP2014.S219.g09612.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term Analysis Definition
Ras-like_Gua-exchang_fac_N CDD Ras-like guanine nucleotide exchange factor, N-terminal
Ras_GEF_dom_sf SUPERFAMILY Ras guanine nucleotide exchange factor domain superfamily
Ras-like_Gua-exchang_fac_N ProSiteProfiles Ras-like guanine nucleotide exchange factor, N-terminal
Ras-like_Gua-exchang_fac_N Pfam Ras-like guanine nucleotide exchange factor, N-terminal

GOSlim

36 results

GO Term Annotation Origin Type
blood vessel development Orthology biological process
protein binding Orthology molecular function
intracellular Orthology cellular component
cytoplasm Orthology cellular component
endosome Orthology cellular component
early endosome Orthology cellular component
cytosol Orthology cellular component
signal transduction Orthology biological process
small GTPase mediated signal transduction Orthology biological process
nervous system development Orthology biological process
cytokine-mediated signaling pathway Orthology biological process
positive regulation of GTPase activity Orthology biological process
perinuclear region of cytoplasm Orthology cellular component
regulation of molecular function Orthology biological process
negative regulation of canonical Wnt signaling pathway Orthology biological process
positive regulation of catalytic activity Orthology biological process
intracellular signal transduction Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
positive regulation of signal transduction Orthology biological process
enzyme binding Orthology molecular function
molecular function regulator Orthology molecular function
cell surface receptor signaling pathway Orthology biological process
neuron projection development Orthology biological process
intracellular organelle part Orthology cellular component
whole membrane Orthology cellular component
cytoplasmic vesicle Orthology cellular component
bounding membrane of organelle Orthology cellular component
cellular response to organic substance Orthology biological process
cellular response to stress Orthology biological process
regulation of signal transduction Orthology biological process
regulation of cellular metabolic process Orthology biological process
protein phosphorylation Orthology biological process
negative regulation of signal transduction Orthology biological process
cell development Orthology biological process
cell adhesion Orthology biological process
negative regulation of cell proliferation Orthology biological process

GO (Orthology)

34 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
activation of MAPKK activity Hs biological process
blood vessel development Hs biological process
guanyl-nucleotide exchange factor activity Hs molecular function
protein binding Hs molecular function
intracellular Hs cellular component
cytoplasm Hs cellular component
endosome Hs cellular component
early endosome Hs cellular component
cytosol Hs cellular component
signal transduction Hs biological process
transmembrane receptor protein tyrosine kinase signaling pathway Hs biological process
small GTPase mediated signal transduction Hs biological process
nervous system development Hs biological process
positive regulation of neuron projection development Hs biological process
Rap guanyl-nucleotide exchange factor activity Hs molecular function
SH3 domain binding Hs molecular function
cytokine-mediated signaling pathway Hs biological process
phagocytic vesicle membrane Hs cellular component
Rap protein signal transduction Hs biological process
nerve growth factor signaling pathway Hs biological process
positive regulation of GTPase activity Hs biological process
regulation of JNK cascade Hs biological process
negative regulation of Ras protein signal transduction Hs biological process
platelet-derived growth factor receptor signaling pathway Hs biological process
perinuclear region of cytoplasm Hs cellular component
negative regulation of protein kinase B signaling Hs biological process
establishment of endothelial barrier Hs biological process
regulation of molecular function Hs biological process
negative regulation of ERK1 and ERK2 cascade Hs biological process
positive regulation of ERK1 and ERK2 cascade Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
cell-cell adhesion Hs biological process
regulation of cell junction assembly Hs biological process
negative regulation of neural precursor cell proliferation Hs biological process

GO (Blast)

11 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
guanyl-nucleotide exchange factor activity Hs molecular function 94.4 1.29e-19
protein binding Hs molecular function 94.4 1.29e-19
intracellular Hs cellular component 94.4 1.29e-19
cytoplasm Hs cellular component 94.4 1.29e-19
endosome Hs cellular component 94.4 1.29e-19
early endosome Hs cellular component 94.4 1.29e-19
cytosol Hs cellular component 94.4 1.29e-19
Rap guanyl-nucleotide exchange factor activity Hs molecular function 94.4 1.29e-19
SH3 domain binding Hs molecular function 94.4 1.29e-19
phagocytic vesicle membrane Hs cellular component 94.4 1.29e-19
perinuclear region of cytoplasm Hs cellular component 94.4 1.29e-19

GO (InterProScan)

No result

GO Term Analysis Type e-value

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