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GENE CARD

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Gene Card

Best human hits

CTBP1; CTBP2; PHGDH

Species

H.roretzi

Unique Gene ID

Harore.g00010278

Gene Model ID

Harore.CG.MTP2014.S115.g10278

Location

S115:247629..251967

Transcript Models and Sequences

  Harore.CG.MTP2014.S115.g10278.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term Analysis Definition
NAD(P)-bd_dom_sf SUPERFAMILY NAD(P)-binding domain superfamily
D-isomer_2_OHA_DH_cat_dom Pfam D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
D-isomer_DH_NAD-bd Pfam D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain

GOSlim

34 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcription corepressor activity Blast molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
protein phosphorylation Orthology biological process
protein C-terminus binding Orthology molecular function
transcription factor binding Orthology molecular function
metabolic process Orthology biological process
negative regulation of cell proliferation Orthology biological process
protein kinase binding Blast molecular function
cell junction Blast cellular component
cell differentiation Orthology biological process
protein homodimerization activity Orthology molecular function
myelin sheath Blast cellular component
macromolecular complex binding Blast molecular function
synapse Blast cellular component
negative regulation of transcription, DNA-templated Orthology biological process
oxidation-reduction process Orthology biological process
extracellular exosome Blast cellular component
intracellular part Orthology cellular component
macromolecular complex Orthology cellular component
catalytic activity Orthology molecular function
organelle organization Orthology biological process
cellular protein modification process Orthology biological process
nucleotide binding Orthology molecular function
coenzyme binding Orthology molecular function
cell cycle Orthology biological process
cellular metabolic process Blast biological process

GO (Orthology)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
RNA polymerase II transcription corepressor activity Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
transcription factor complex Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
protein phosphorylation Hs biological process
protein C-terminus binding Hs molecular function
transcription factor binding Hs molecular function
metabolic process Hs biological process
negative regulation of cell proliferation Hs biological process
viral process Hs biological process
oxidoreductase activity Hs molecular function
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Hs molecular function
hydroxypyruvate reductase activity Hs molecular function
transcriptional repressor complex Hs cellular component
viral genome replication Hs biological process
protein domain specific binding Hs molecular function
cell differentiation Hs biological process
glyoxylate reductase (NADP) activity Hs molecular function
positive regulation of histone deacetylation Hs biological process
negative regulation of histone acetylation Hs biological process
protein homodimerization activity Hs molecular function
negative regulation of transcription, DNA-templated Hs biological process
NAD binding Hs molecular function
regulation of cell cycle Hs biological process
oxidation-reduction process Hs biological process
repressing transcription factor binding Hs molecular function

GO (Blast)

29 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
RNA polymerase II transcription corepressor activity Hs molecular function 530 0.0
transcription factor activity, sequence-specific DNA binding Hs molecular function 530 0.0
transcription corepressor activity Hs molecular function 531 1.21e-178
phosphoglycerate dehydrogenase activity Hs molecular function 133 4.58e-33
protein binding Hs molecular function 531 1.21e-178
nucleus Hs cellular component 531 1.21e-178
nucleoplasm Hs cellular component 530 0.0
transcription factor complex Hs cellular component 530 0.0
cytoplasm Hs cellular component 530 0.0
cytosol Hs cellular component 531 1.21e-178
protein C-terminus binding Hs molecular function 530 0.0
transcription factor binding Hs molecular function 530 0.0
electron carrier activity Hs molecular function 133 4.58e-33
oxidoreductase activity Hs molecular function 531 1.21e-178
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Hs molecular function 531 1.21e-178
hydroxypyruvate reductase activity Hs molecular function 531 1.21e-178
transcriptional repressor complex Hs cellular component 531 1.21e-178
protein kinase binding Hs molecular function 531 1.21e-178
protein domain specific binding Hs molecular function 530 0.0
cell junction Hs cellular component 531 1.21e-178
L-malate dehydrogenase activity Hs molecular function 133 4.58e-33
glyoxylate reductase (NADP) activity Hs molecular function 531 1.21e-178
protein homodimerization activity Hs molecular function 531 1.21e-178
myelin sheath Hs cellular component 133 4.58e-33
macromolecular complex binding Hs molecular function 531 1.21e-178
synapse Hs cellular component 531 1.21e-178
NAD binding Hs molecular function 531 1.21e-178
extracellular exosome Hs cellular component 133 4.58e-33
repressing transcription factor binding Hs molecular function 530 0.0

GO (InterProScan)

4 results

GO Term Analysis Type e-value
metabolic process Pfam biological process 2.2E-26
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Pfam molecular function 2.2E-26
NAD binding Pfam molecular function 2.6E-52
oxidation-reduction process Pfam biological process 2.6E-52