Gene Card
Best human hits
PYCR1; PYCR2; PYCR3
Species
Unique Gene ID
Harore.g00011305
Gene Model ID
Harore.CG.MTP2014.S30.g11305
Location
S30:187150..189755
Transcript Models and Sequences
Harore.CG.MTP2014.S30.g11305.01.t
Harore.CG.MTP2014.S30.g11305.02.t
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
7 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Pyrroline-COOH_reductase | PIRSF | Pyrroline-5-carboxylate reductase |
| P5C_Rdtase_cat_N | Pfam | Pyrroline-5-carboxylate reductase, catalytic, N-terminal |
| 6-PGluconate_DH-like_C_sf | SUPERFAMILY | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily |
| P5CR_dimer | Pfam | Pyrroline-5-carboxylate reductase, dimerisation domain |
| Pyrroline-COOH_reductase | Hamap | Pyrroline-5-carboxylate reductase |
| NAD(P)-bd_dom_sf | SUPERFAMILY | NAD(P)-binding domain superfamily |
| Pyrroline-COOH_reductase | TIGRFAM | Pyrroline-5-carboxylate reductase |
GOSlim
12 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| protein binding | Orthology | molecular function |
| cytoplasm | Orthology | cellular component |
| mitochondrion | Orthology | cellular component |
| mitochondrial matrix | Orthology | cellular component |
| cytosol | Blast | cellular component |
| identical protein binding | Orthology | molecular function |
| oxidation-reduction process | Orthology | biological process |
| catalytic activity | Orthology | molecular function |
| cellular biosynthetic process | Orthology | biological process |
| cellular response to stress | Orthology | biological process |
| response to oxidative stress | Orthology | biological process |
| negative regulation of cell death | Orthology | biological process |
GO (Orthology)
14 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| pyrroline-5-carboxylate reductase activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| cytoplasm | Hs | cellular component |
| mitochondrion | Hs | cellular component |
| mitochondrial matrix | Hs | cellular component |
| proline biosynthetic process | Hs | biological process |
| cellular amino acid biosynthetic process | Hs | biological process |
| oxidoreductase activity | Hs | molecular function |
| cellular response to oxidative stress | Hs | biological process |
| identical protein binding | Hs | molecular function |
| regulation of mitochondrial membrane potential | Hs | biological process |
| oxidation-reduction process | Hs | biological process |
| L-proline biosynthetic process | Hs | biological process |
| negative regulation of hydrogen peroxide-induced cell death | Hs | biological process |
GO (Blast)
8 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| pyrroline-5-carboxylate reductase activity | Hs | molecular function | 320 | 1.52e-109 |
| protein binding | Hs | molecular function | 320 | 1.52e-109 |
| cytoplasm | Hs | cellular component | 318 | 5.98e-109 |
| mitochondrion | Hs | cellular component | 320 | 1.52e-109 |
| mitochondrial matrix | Hs | cellular component | 320 | 1.52e-109 |
| cytosol | Hs | cellular component | 215 | 5.95e-69 |
| oxidoreductase activity | Hs | molecular function | 320 | 1.52e-109 |
| identical protein binding | Hs | molecular function | 320 | 1.52e-109 |
GO (InterProScan)
3 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| pyrroline-5-carboxylate reductase activity | PIRSF | molecular function | 3.8E-82 |
| proline biosynthetic process | PIRSF | biological process | 3.8E-82 |
| oxidation-reduction process | PIRSF | biological process | 3.8E-82 |
