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GENE CARD

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Gene Card

Best human hits

PNPLA1; PNPLA2; PNPLA3

Species

H.roretzi

Unique Gene ID

Harore.g00011880

Gene Model ID

Harore.CG.MTP2014.S109.g11880

Location

S109:54379..56269

Transcript Models and Sequences

  Harore.CG.MTP2014.S109.g11880.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term Analysis Definition
PLPL PANTHER Patatin-like phospholipase domain-containing protein
PNPLA_dom ProSiteProfiles Patatin-like phospholipase domain
PNPLA_dom Pfam Patatin-like phospholipase domain
Acyl_Trfase/lysoPLipase SUPERFAMILY Acyl transferase/acyl hydrolase/lysophospholipase

GOSlim

22 results

GO Term Annotation Origin Type
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
endoplasmic reticulum lumen Orthology cellular component
endoplasmic reticulum membrane Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
metabolic process Orthology biological process
membrane Orthology cellular component
integral component of membrane Orthology cellular component
transferase activity Orthology molecular function
hydrolase activity Orthology molecular function
cellular metabolic process Orthology biological process
organic substance metabolic process Orthology biological process
intracellular non-membrane-bounded organelle Orthology cellular component
phosphate-containing compound metabolic process Orthology biological process
cellular biosynthetic process Orthology biological process
organelle organization Orthology biological process
anion binding Orthology molecular function
carbohydrate derivative binding Orthology molecular function
adenyl ribonucleotide binding Orthology molecular function
coenzyme binding Orthology molecular function
cellular protein modification process Orthology biological process

GO (Orthology)

35 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
long-chain fatty acid metabolic process Hs biological process
lipoprotein lipase activity Hs molecular function
phospholipase A2 activity Hs molecular function
triglyceride lipase activity Hs molecular function
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
endoplasmic reticulum lumen Hs cellular component
endoplasmic reticulum membrane Hs cellular component
lipid droplet Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
lipid metabolic process Hs biological process
glycerophospholipid metabolic process Hs biological process
phosphatidic acid biosynthetic process Hs biological process
metabolic process Hs biological process
negative regulation of sequestering of triglyceride Hs biological process
positive regulation of triglyceride catabolic process Hs biological process
membrane Hs cellular component
integral component of membrane Hs cellular component
lipid catabolic process Hs biological process
acylglycerol O-acyltransferase activity Hs molecular function
transferase activity Hs molecular function
transferase activity, transferring acyl groups Hs molecular function
hydrolase activity Hs molecular function
triglyceride biosynthetic process Hs biological process
triglyceride catabolic process Hs biological process
lipid storage Hs biological process
lipid particle organization Hs biological process
lysophosphatidic acid binding Hs molecular function
long-chain fatty acyl-CoA binding Hs molecular function
lysophosphatidic acid acyltransferase activity Hs molecular function
post-translational protein modification Hs biological process
mono-olein transacylation activity Hs molecular function
diolein transacylation activity Hs molecular function
lipid homeostasis Hs biological process

GO (Blast)

21 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
lipoprotein lipase activity Hs molecular function 251 3.15e-76
phospholipase A2 activity Hs molecular function 202 8.22e-58
triglyceride lipase activity Hs molecular function 251 3.15e-76
nucleoplasm Hs cellular component 251 3.15e-76
cytoplasm Hs cellular component 251 3.15e-76
endoplasmic reticulum lumen Hs cellular component 251 3.15e-76
endoplasmic reticulum membrane Hs cellular component 251 3.15e-76
lipid droplet Hs cellular component 251 3.15e-76
cytosol Hs cellular component 251 3.15e-76
plasma membrane Hs cellular component 251 3.15e-76
membrane Hs cellular component 251 3.15e-76
integral component of membrane Hs cellular component 251 3.15e-76
acylglycerol O-acyltransferase activity Hs molecular function 251 3.15e-76
transferase activity Hs molecular function 202 8.22e-58
transferase activity, transferring acyl groups Hs molecular function 202 8.22e-58
hydrolase activity Hs molecular function 251 3.15e-76
lysophosphatidic acid binding Hs molecular function 202 8.22e-58
long-chain fatty acyl-CoA binding Hs molecular function 202 8.22e-58
lysophosphatidic acid acyltransferase activity Hs molecular function 202 8.22e-58
mono-olein transacylation activity Hs molecular function 202 8.22e-58
diolein transacylation activity Hs molecular function 202 8.22e-58

GO (InterProScan)

4 results

GO Term Analysis Type e-value
lipid metabolic process Pfam biological process 6.8E-7
metabolic process SUPERFAMILY biological process 1.86E-42
lipid catabolic process PANTHER biological process 1.3E-108
hydrolase activity PANTHER molecular function 1.3E-108