Gene Card
Best human hits
PNPLA1; PNPLA2; PNPLA3
Species
Unique Gene ID
Harore.g00011880
Gene Model ID
Harore.CG.MTP2014.S109.g11880
Location
S109:54379..56269
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
PLPL | PANTHER | Patatin-like phospholipase domain-containing protein |
PNPLA_dom | ProSiteProfiles | Patatin-like phospholipase domain |
PNPLA_dom | Pfam | Patatin-like phospholipase domain |
Acyl_Trfase/lysoPLipase | SUPERFAMILY | Acyl transferase/acyl hydrolase/lysophospholipase |
GO Term | Annotation Origin | Type |
---|---|---|
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
endoplasmic reticulum lumen | Orthology | cellular component |
endoplasmic reticulum membrane | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
metabolic process | Orthology | biological process |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
transferase activity | Orthology | molecular function |
hydrolase activity | Orthology | molecular function |
cellular metabolic process | Orthology | biological process |
organic substance metabolic process | Orthology | biological process |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
phosphate-containing compound metabolic process | Orthology | biological process |
cellular biosynthetic process | Orthology | biological process |
organelle organization | Orthology | biological process |
anion binding | Orthology | molecular function |
carbohydrate derivative binding | Orthology | molecular function |
adenyl ribonucleotide binding | Orthology | molecular function |
coenzyme binding | Orthology | molecular function |
cellular protein modification process | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
long-chain fatty acid metabolic process | Hs | biological process |
lipoprotein lipase activity | Hs | molecular function |
phospholipase A2 activity | Hs | molecular function |
triglyceride lipase activity | Hs | molecular function |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
endoplasmic reticulum lumen | Hs | cellular component |
endoplasmic reticulum membrane | Hs | cellular component |
lipid droplet | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
lipid metabolic process | Hs | biological process |
glycerophospholipid metabolic process | Hs | biological process |
phosphatidic acid biosynthetic process | Hs | biological process |
metabolic process | Hs | biological process |
negative regulation of sequestering of triglyceride | Hs | biological process |
positive regulation of triglyceride catabolic process | Hs | biological process |
membrane | Hs | cellular component |
integral component of membrane | Hs | cellular component |
lipid catabolic process | Hs | biological process |
acylglycerol O-acyltransferase activity | Hs | molecular function |
transferase activity | Hs | molecular function |
transferase activity, transferring acyl groups | Hs | molecular function |
hydrolase activity | Hs | molecular function |
triglyceride biosynthetic process | Hs | biological process |
triglyceride catabolic process | Hs | biological process |
lipid storage | Hs | biological process |
lipid particle organization | Hs | biological process |
lysophosphatidic acid binding | Hs | molecular function |
long-chain fatty acyl-CoA binding | Hs | molecular function |
lysophosphatidic acid acyltransferase activity | Hs | molecular function |
post-translational protein modification | Hs | biological process |
mono-olein transacylation activity | Hs | molecular function |
diolein transacylation activity | Hs | molecular function |
lipid homeostasis | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
lipoprotein lipase activity | Hs | molecular function | 251 | 3.15e-76 |
phospholipase A2 activity | Hs | molecular function | 202 | 8.22e-58 |
triglyceride lipase activity | Hs | molecular function | 251 | 3.15e-76 |
nucleoplasm | Hs | cellular component | 251 | 3.15e-76 |
cytoplasm | Hs | cellular component | 251 | 3.15e-76 |
endoplasmic reticulum lumen | Hs | cellular component | 251 | 3.15e-76 |
endoplasmic reticulum membrane | Hs | cellular component | 251 | 3.15e-76 |
lipid droplet | Hs | cellular component | 251 | 3.15e-76 |
cytosol | Hs | cellular component | 251 | 3.15e-76 |
plasma membrane | Hs | cellular component | 251 | 3.15e-76 |
membrane | Hs | cellular component | 251 | 3.15e-76 |
integral component of membrane | Hs | cellular component | 251 | 3.15e-76 |
acylglycerol O-acyltransferase activity | Hs | molecular function | 251 | 3.15e-76 |
transferase activity | Hs | molecular function | 202 | 8.22e-58 |
transferase activity, transferring acyl groups | Hs | molecular function | 202 | 8.22e-58 |
hydrolase activity | Hs | molecular function | 251 | 3.15e-76 |
lysophosphatidic acid binding | Hs | molecular function | 202 | 8.22e-58 |
long-chain fatty acyl-CoA binding | Hs | molecular function | 202 | 8.22e-58 |
lysophosphatidic acid acyltransferase activity | Hs | molecular function | 202 | 8.22e-58 |
mono-olein transacylation activity | Hs | molecular function | 202 | 8.22e-58 |
diolein transacylation activity | Hs | molecular function | 202 | 8.22e-58 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
lipid metabolic process | Pfam | biological process | 6.8E-7 |
metabolic process | SUPERFAMILY | biological process | 1.86E-42 |
lipid catabolic process | PANTHER | biological process | 1.3E-108 |
hydrolase activity | PANTHER | molecular function | 1.3E-108 |