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Gene Card

Best human hits

PSMC2; PSMC5; PSMC6

Species

H.roretzi

Unique Gene ID

Harore.g00012867

Gene Model ID

Harore.CG.MTP2014.S140.g12867

Location

S140:112610..115393

Transcript Models and Sequences

  Harore.CG.MTP2014.S140.g12867.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term Analysis Definition
AAA+_ATPase SMART AAA+ ATPase domain
ATPase_AAA_CS ProSitePatterns ATPase, AAA-type, conserved site
P-loop_NTPase SUPERFAMILY P-loop containing nucleoside triphosphate hydrolase
ATPase_AAA_core Pfam ATPase, AAA-type, core
PSMC6 PANTHER 26S proteasome regulatory subunit 10B
26S_Psome_P45-like TIGRFAM 26S proteasome regulatory subunit P45-like

GOSlim

51 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
protein polyubiquitination Orthology biological process
receptor binding Blast molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
extracellular region Blast cellular component
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
transcription factor binding Orthology molecular function
membrane Orthology cellular component
hydrolase activity Orthology molecular function
cytoplasmic vesicle Blast cellular component
identical protein binding Orthology molecular function
transmembrane transport Orthology biological process
extracellular exosome Orthology cellular component
negative regulation of canonical Wnt signaling pathway Orthology biological process
positive regulation of canonical Wnt signaling pathway Orthology biological process
postsynapse Blast cellular component
intracellular signal transduction Orthology biological process
protein phosphorylation Orthology biological process
intracellular part Orthology cellular component
macromolecular complex Orthology cellular component
proteolysis Orthology biological process
G2/M transition of mitotic cell cycle Orthology biological process
peptidase activity, acting on L-amino acid peptides Orthology molecular function
nucleoside-triphosphatase activity Orthology molecular function
protein metabolic process Orthology biological process
cellular response to stress Orthology biological process
response to organic substance Orthology biological process
nuclear lumen Orthology cellular component
cytokine-mediated signaling pathway Orthology biological process
transcription factor activity, sequence-specific DNA binding Orthology molecular function
cell surface receptor signaling pathway Orthology biological process
immune response Orthology biological process
mRNA catabolic process Orthology biological process
cellular protein modification process Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
transcription initiation from RNA polymerase II promoter Orthology biological process
cell-cell signaling Orthology biological process
anatomical structure morphogenesis Orthology biological process
animal organ development Orthology biological process
immune system process Orthology biological process
cell differentiation Orthology biological process
cytoplasmic part Blast cellular component
intracellular non-membrane-bounded organelle Blast cellular component
intracellular organelle part Blast cellular component
endomembrane system Blast cellular component
intracellular organelle lumen Blast cellular component
extracellular space Blast cellular component

GO (Orthology)

46 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
MAPK cascade Hs biological process
nucleotide binding Hs molecular function
protein polyubiquitination Hs biological process
proteasome complex Hs cellular component
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
ubiquitin-dependent protein catabolic process Hs biological process
proteasome regulatory particle, base subcomplex Hs cellular component
negative regulation of G2/M transition of mitotic cell cycle Hs biological process
membrane Hs cellular component
inclusion body Hs cellular component
protein deubiquitination Hs biological process
hydrolase activity Hs molecular function
ATPase activity Hs molecular function
TBP-class protein binding Hs molecular function
proteasome accessory complex Hs cellular component
protein catabolic process Hs biological process
ubiquitin-dependent ERAD pathway Hs biological process
protein binding, bridging Hs molecular function
anaphase-promoting complex-dependent catabolic process Hs biological process
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Hs biological process
nuclear proteasome complex Hs cellular component
cytosolic proteasome complex Hs cellular component
tumor necrosis factor-mediated signaling pathway Hs biological process
proteasome-activating ATPase activity Hs molecular function
NIK/NF-kappaB signaling Hs biological process
Fc-epsilon receptor signaling pathway Hs biological process
identical protein binding Hs molecular function
proteasome-mediated ubiquitin-dependent protein catabolic process Hs biological process
regulation of mRNA stability Hs biological process
post-translational protein modification Hs biological process
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly Hs biological process
T cell receptor signaling pathway Hs biological process
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Hs biological process
transmembrane transport Hs biological process
Wnt signaling pathway, planar cell polarity pathway Hs biological process
extracellular exosome Hs cellular component
interleukin-1-mediated signaling pathway Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
positive regulation of canonical Wnt signaling pathway Hs biological process
positive regulation of proteasomal protein catabolic process Hs biological process
regulation of hematopoietic stem cell differentiation Hs biological process

GO (Blast)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 710 0.0
proteasome complex Hs cellular component 710 0.0
P-body Hs cellular component 340 1.70e-114
receptor binding Hs molecular function 328 4.82e-110
protein binding Hs molecular function 710 0.0
ATP binding Hs molecular function 710 0.0
extracellular region Hs cellular component 340 1.70e-114
nucleus Hs cellular component 710 0.0
nucleoplasm Hs cellular component 710 0.0
cytoplasm Hs cellular component 710 0.0
cytosol Hs cellular component 710 0.0
proteasome regulatory particle Hs cellular component 328 4.82e-110
transcription factor binding Hs molecular function 328 4.82e-110
proteasome regulatory particle, base subcomplex Hs cellular component 710 0.0
membrane Hs cellular component 710 0.0
inclusion body Hs cellular component 710 0.0
hydrolase activity Hs molecular function 710 0.0
ATPase activity Hs molecular function 710 0.0
TBP-class protein binding Hs molecular function 710 0.0
proteasome accessory complex Hs cellular component 710 0.0
protein binding, bridging Hs molecular function 710 0.0
cytoplasmic vesicle Hs cellular component 328 4.82e-110
thyrotropin-releasing hormone receptor binding Hs molecular function 328 4.82e-110
nuclear proteasome complex Hs cellular component 710 0.0
cytosolic proteasome complex Hs cellular component 710 0.0
secretory granule lumen Hs cellular component 340 1.70e-114
proteasome-activating ATPase activity Hs molecular function 710 0.0
cytoplasmic ribonucleoprotein granule Hs cellular component 340 1.70e-114
identical protein binding Hs molecular function 710 0.0
extracellular exosome Hs cellular component 710 0.0
blood microparticle Hs cellular component 328 4.82e-110
postsynapse Hs cellular component 328 4.82e-110
ficolin-1-rich granule lumen Hs cellular component 340 1.70e-114

GO (InterProScan)

5 results

GO Term Analysis Type e-value
ATP binding Pfam molecular function 1.7E-43
cytoplasm TIGRFAM cellular component 3.5E-134
hydrolase activity TIGRFAM molecular function 3.5E-134
protein catabolic process TIGRFAM biological process 3.5E-134
proteasome-activating ATPase activity PANTHER molecular function 5.6E-215

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