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GENE CARD

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Gene Card

Best human hits

RAC1; RAC2; RAC3

Species

H.roretzi

Unique Gene ID

Harore.g00013578

Gene Model ID

Harore.CG.MTP2014.S18.g13578

Location

S18:268315..271016

Transcript Models and Sequences

  Harore.CG.MTP2014.S18.g13578.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term Analysis Definition
Small_GTPase Pfam Small GTPase superfamily
Small_GTPase_Rho ProSiteProfiles Small GTPase superfamily, Rho type
P-loop_NTPase SUPERFAMILY P-loop containing nucleoside triphosphate hydrolase
Small_GTP-bd_dom TIGRFAM Small GTP-binding protein domain

GOSlim

84 results

GO Term Annotation Origin Type
Golgi membrane Orthology cellular component
nucleotide binding Orthology molecular function
GTPase activity Orthology molecular function
protein serine/threonine kinase activity Orthology molecular function
protein binding Orthology molecular function
GTP binding Orthology molecular function
intracellular Orthology cellular component
nuclear envelope Orthology cellular component
cytoplasm Orthology cellular component
endoplasmic reticulum membrane Orthology cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
plasma membrane Orthology cellular component
focal adhesion Orthology cellular component
protein phosphorylation Orthology biological process
chemotaxis Orthology biological process
cell adhesion Orthology biological process
signal transduction Orthology biological process
G-protein coupled receptor signaling pathway Orthology biological process
small GTPase mediated signal transduction Orthology biological process
blood coagulation Orthology biological process
cell proliferation Orthology biological process
positive regulation of cell proliferation Orthology biological process
response to wounding Orthology biological process
anatomical structure morphogenesis Orthology biological process
endomembrane system Orthology cellular component
membrane Orthology cellular component
enzyme binding Orthology molecular function
protein kinase binding Orthology molecular function
lamellipodium Orthology cellular component
cell projection assembly Orthology biological process
neuron projection development Orthology biological process
cytoplasmic vesicle Orthology cellular component
intracellular signal transduction Orthology biological process
melanosome Orthology cellular component
cell projection Orthology cellular component
neuron projection Orthology cellular component
neuronal cell body Orthology cellular component
positive regulation of apoptotic process Orthology biological process
perinuclear region of cytoplasm Orthology cellular component
cell motility Orthology biological process
extracellular exosome Orthology cellular component
cell periphery Orthology cellular component
Golgi apparatus part Orthology cellular component
cytoskeletal part Orthology cellular component
defense response Orthology biological process
organelle organization Orthology biological process
cellular component organization Orthology biological process
regulation of cellular metabolic process Orthology biological process
protein kinase activity Orthology molecular function
enzyme regulator activity Orthology molecular function
cell morphogenesis Orthology biological process
cellular process Orthology biological process
cell migration Orthology biological process
cell projection part Orthology cellular component
axon Orthology cellular component
intracellular organelle part Orthology cellular component
whole membrane Orthology cellular component
bounding membrane of organelle Orthology cellular component
microtubule-based process Orthology biological process
cell projection organization Orthology biological process
macromolecular complex Orthology cellular component
cell projection membrane Orthology cellular component
cell leading edge Orthology cellular component
cell morphogenesis involved in differentiation Orthology biological process
positive regulation of signal transduction Orthology biological process
cytoplasmic part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
cell surface receptor signaling pathway Orthology biological process
immune response Orthology biological process
regulation of cell proliferation Orthology biological process
immune system process Orthology biological process
postsynapse Orthology cellular component
intracellular transport Orthology biological process
membrane organization Orthology biological process
lysosome Orthology cellular component
DNA replication Orthology biological process
regulation of catalytic activity Orthology biological process
nervous system process Orthology biological process
regulation of signal transduction Orthology biological process
chemical synaptic transmission Orthology biological process
endosome Orthology cellular component
cell-cell signaling Orthology biological process
animal organ development Orthology biological process

GO (Orthology)

108 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
Golgi membrane Hs cellular component
nucleotide binding Hs molecular function
positive regulation of protein phosphorylation Hs biological process
GTPase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
protein binding Hs molecular function
GTP binding Hs molecular function
intracellular Hs cellular component
nuclear envelope Hs cellular component
cytoplasm Hs cellular component
endoplasmic reticulum membrane Hs cellular component
trans-Golgi network Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
actin filament Hs cellular component
plasma membrane Hs cellular component
focal adhesion Hs cellular component
protein phosphorylation Hs biological process
chemotaxis Hs biological process
inflammatory response Hs biological process
actin filament organization Hs biological process
cell adhesion Hs biological process
cell-matrix adhesion Hs biological process
signal transduction Hs biological process
G-protein coupled receptor signaling pathway Hs biological process
small GTPase mediated signal transduction Hs biological process
blood coagulation Hs biological process
cell proliferation Hs biological process
positive regulation of cell proliferation Hs biological process
regulation of cell size Hs biological process
response to wounding Hs biological process
anatomical structure morphogenesis Hs biological process
regulation of hydrogen peroxide metabolic process Hs biological process
regulation of lamellipodium assembly Hs biological process
positive regulation of lamellipodium assembly Hs biological process
positive regulation of cell-substrate adhesion Hs biological process
endomembrane system Hs cellular component
membrane Hs cellular component
Rac protein signal transduction Hs biological process
Rab GTPase binding Hs molecular function
protein kinase regulator activity Hs molecular function
enzyme binding Hs molecular function
protein kinase binding Hs molecular function
regulation of cell morphogenesis Hs biological process
lamellipodium Hs cellular component
cell projection assembly Hs biological process
lamellipodium assembly Hs biological process
actin cytoskeleton organization Hs biological process
actin filament polymerization Hs biological process
platelet activation Hs biological process
regulation of cell migration Hs biological process
growth cone Hs cellular component
secretory granule membrane Hs cellular component
phagocytic vesicle membrane Hs cellular component
positive regulation of microtubule polymerization Hs biological process
neuron projection development Hs biological process
cytoplasmic vesicle Hs cellular component
ruffle organization Hs biological process
filamentous actin Hs cellular component
thioesterase binding Hs molecular function
ruffle membrane Hs cellular component
positive regulation of cell adhesion mediated by integrin Hs biological process
substrate adhesion-dependent cell spreading Hs biological process
positive regulation of Rho protein signal transduction Hs biological process
intracellular signal transduction Hs biological process
cytoplasmic ribonucleoprotein granule Hs cellular component
Fc-epsilon receptor signaling pathway Hs biological process
regulation of T cell proliferation Hs biological process
melanosome Hs cellular component
histone deacetylase binding Hs molecular function
cell projection Hs cellular component
neuron projection Hs cellular component
neuronal cell body Hs cellular component
positive regulation of apoptotic process Hs biological process
dendritic spine Hs cellular component
regulation of mast cell degranulation Hs biological process
bone resorption Hs biological process
positive regulation of DNA replication Hs biological process
regulation of protein kinase activity Hs biological process
vascular endothelial growth factor receptor signaling pathway Hs biological process
hepatocyte growth factor receptor signaling pathway Hs biological process
ephrin receptor signaling pathway Hs biological process
negative regulation of receptor-mediated endocytosis Hs biological process
calcium-dependent protein binding Hs molecular function
perinuclear region of cytoplasm Hs cellular component
cell motility Hs biological process
homeostasis of number of cells within a tissue Hs biological process
neuromuscular process controlling balance Hs biological process
neuromuscular process Hs biological process
Rho GDP-dissociation inhibitor binding Hs molecular function
regulation of small GTPase mediated signal transduction Hs biological process
ATPase binding Hs molecular function
regulation of stress fiber assembly Hs biological process
positive regulation of stress fiber assembly Hs biological process
localization within membrane Hs biological process
positive regulation of focal adhesion assembly Hs biological process
synaptic transmission, GABAergic Hs biological process
recycling endosome membrane Hs cellular component
Wnt signaling pathway, planar cell polarity pathway Hs biological process
extracellular exosome Hs cellular component
cellular response to mechanical stimulus Hs biological process
semaphorin-plexin signaling pathway Hs biological process
cell periphery Hs cellular component
positive regulation of neutrophil chemotaxis Hs biological process
ruffle assembly Hs biological process
ficolin-1-rich granule membrane Hs cellular component
positive regulation of substrate adhesion-dependent cell spreading Hs biological process
regulation of neutrophil migration Hs biological process

GO (Blast)

45 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
Golgi membrane Hs cellular component 347 1.05e-122
nucleotide binding Hs molecular function 355 4.42e-126
GTPase activity Hs molecular function 355 4.42e-126
protein serine/threonine kinase activity Hs molecular function 347 1.05e-122
protein binding Hs molecular function 355 4.42e-126
GTP binding Hs molecular function 355 4.42e-126
intracellular Hs cellular component 355 4.42e-126
nuclear envelope Hs cellular component 355 4.42e-126
cytoplasm Hs cellular component 355 4.42e-126
endoplasmic reticulum membrane Hs cellular component 347 1.05e-122
trans-Golgi network Hs cellular component 347 1.05e-122
cytosol Hs cellular component 355 4.42e-126
cytoskeleton Hs cellular component 341 1.23e-120
actin filament Hs cellular component 355 4.42e-126
plasma membrane Hs cellular component 355 4.42e-126
focal adhesion Hs cellular component 355 4.42e-126
endomembrane system Hs cellular component 341 1.23e-120
membrane Hs cellular component 355 4.42e-126
Rab GTPase binding Hs molecular function 347 1.05e-122
protein kinase regulator activity Hs molecular function 355 4.42e-126
enzyme binding Hs molecular function 347 1.05e-122
protein kinase binding Hs molecular function 347 1.05e-122
lamellipodium Hs cellular component 355 4.42e-126
growth cone Hs cellular component 341 1.23e-120
secretory granule membrane Hs cellular component 347 1.05e-122
phagocytic vesicle membrane Hs cellular component 355 4.42e-126
cytoplasmic vesicle Hs cellular component 347 1.05e-122
filamentous actin Hs cellular component 341 1.23e-120
thioesterase binding Hs molecular function 347 1.05e-122
ruffle membrane Hs cellular component 347 1.05e-122
cytoplasmic ribonucleoprotein granule Hs cellular component 347 1.05e-122
melanosome Hs cellular component 347 1.05e-122
histone deacetylase binding Hs molecular function 347 1.05e-122
cell projection Hs cellular component 341 1.23e-120
neuron projection Hs cellular component 341 1.23e-120
neuronal cell body Hs cellular component 341 1.23e-120
dendritic spine Hs cellular component 347 1.05e-122
calcium-dependent protein binding Hs molecular function 341 1.23e-120
perinuclear region of cytoplasm Hs cellular component 341 1.23e-120
Rho GDP-dissociation inhibitor binding Hs molecular function 347 1.05e-122
ATPase binding Hs molecular function 347 1.05e-122
recycling endosome membrane Hs cellular component 347 1.05e-122
extracellular exosome Hs cellular component 355 4.42e-126
cell periphery Hs cellular component 341 1.23e-120
ficolin-1-rich granule membrane Hs cellular component 347 1.05e-122

GO (InterProScan)

4 results

GO Term Analysis Type e-value
GTPase activity Pfam molecular function 2.3E-53
GTP binding Pfam molecular function 2.3E-53
intracellular ProSiteProfiles cellular component 28.428
small GTPase mediated signal transduction ProSiteProfiles biological process 28.428