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Gene Card

Best human hits

MERTK; MET; MST1R

Species

H.roretzi

Unique Gene ID

Harore.g00013616

Gene Model ID

Harore.CG.MTP2014.S151.g13616

Location

S151:113376..128733

Transcript Models and Sequences

  Harore.CG.MTP2014.S151.g13616.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

16 results

IPR Term Analysis Definition
Tyr_kinase_cat_dom SMART Tyrosine-protein kinase, catalytic domain
Semap_dom SMART Sema domain
Semap_dom_sf SUPERFAMILY Sema domain superfamily
WD40/YVTN_repeat-like_dom_sf Gene3D WD40/YVTN repeat-like-containing domain superfamily
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
Tyr_kinase_AS ProSitePatterns Tyrosine-protein kinase, active site
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Ig_E-set SUPERFAMILY Immunoglobulin E-set
IPT_dom SMART IPT domain
Semap_dom Pfam Sema domain
Semap_dom ProSiteProfiles Sema domain
Ser-Thr/Tyr_kinase_cat_dom PRINTS Serine-threonine/tyrosine-protein kinase, catalytic domain
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Ig-like_fold Gene3D Immunoglobulin-like fold
IPT_dom Pfam IPT domain

GOSlim

54 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
immune system process Orthology biological process
protein kinase activity Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Blast cellular component
intracellular Orthology cellular component
cytoplasm Blast cellular component
vacuole Orthology cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Orthology cellular component
protein phosphorylation Orthology biological process
defense response Orthology biological process
signal transduction Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cell proliferation Orthology biological process
positive regulation of cell proliferation Orthology biological process
cell surface Orthology cellular component
membrane Orthology cellular component
integral component of membrane Orthology cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
transferase activity Orthology molecular function
enzyme binding Orthology molecular function
identical protein binding Orthology molecular function
innate immune response Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
intracellular signal transduction Orthology biological process
cytoskeletal part Orthology cellular component
transmembrane signaling receptor activity Orthology molecular function
cytokine-mediated signaling pathway Orthology biological process
molecular function regulator Orthology molecular function
sexual reproduction Orthology biological process
basolateral plasma membrane Orthology cellular component
organelle organization Orthology biological process
microtubule-based process Orthology biological process
small GTPase mediated signal transduction Orthology biological process
negative regulation of signal transduction Orthology biological process
positive regulation of catalytic activity Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
positive regulation of signal transduction Orthology biological process
organic substance metabolic process Orthology biological process
phosphotransferase activity, alcohol group as acceptor Orthology molecular function
anatomical structure morphogenesis Orthology biological process
multicellular organism development Orthology biological process
chemotaxis Orthology biological process
animal organ development Orthology biological process
organelle part Blast cellular component
cell projection part Blast cellular component
neuron projection Blast cellular component
macromolecular complex Blast cellular component
cell projection Blast cellular component
plasma membrane region Blast cellular component

GO (Orthology)

52 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
MAPK cascade Hs biological process
nucleotide binding Hs molecular function
stress fiber Hs cellular component
immune system process Hs biological process
protein kinase activity Hs molecular function
protein tyrosine kinase activity Hs molecular function
transmembrane receptor protein tyrosine kinase activity Hs molecular function
hepatocyte growth factor-activated receptor activity Hs molecular function
macrophage colony-stimulating factor receptor activity Hs molecular function
Ras guanyl-nucleotide exchange factor activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
extracellular region Hs cellular component
intracellular Hs cellular component
vacuole Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
protein phosphorylation Hs biological process
defense response Hs biological process
signal transduction Hs biological process
cell surface receptor signaling pathway Hs biological process
transmembrane receptor protein tyrosine kinase signaling pathway Hs biological process
single fertilization Hs biological process
cell proliferation Hs biological process
positive regulation of cell proliferation Hs biological process
response to virus Hs biological process
basal plasma membrane Hs cellular component
cell surface Hs cellular component
negative regulation of autophagy Hs biological process
membrane Hs cellular component
integral component of membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
transferase activity Hs molecular function
peptidyl-tyrosine phosphorylation Hs biological process
enzyme binding Hs molecular function
protein phosphatase binding Hs molecular function
positive regulation of microtubule polymerization Hs biological process
negative regulation of Rho protein signal transduction Hs biological process
identical protein binding Hs molecular function
positive regulation of MAP kinase activity Hs biological process
innate immune response Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
phosphatidylinositol phosphorylation Hs biological process
phosphatidylinositol-4,5-bisphosphate 3-kinase activity Hs molecular function
hepatocyte growth factor receptor signaling pathway Hs biological process
branching morphogenesis of an epithelial tube Hs biological process
positive chemotaxis Hs biological process
negative regulation of stress fiber assembly Hs biological process
positive regulation of protein kinase B signaling Hs biological process
establishment of skin barrier Hs biological process
semaphorin-plexin signaling pathway Hs biological process

GO (Blast)

29 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 466 3.18e-140
stress fiber Hs cellular component 331 3.41e-93
photoreceptor outer segment Hs cellular component 242 1.53e-65
protein kinase activity Hs molecular function 466 3.18e-140
protein tyrosine kinase activity Hs molecular function 466 3.18e-140
transmembrane receptor protein tyrosine kinase activity Hs molecular function 466 3.18e-140
hepatocyte growth factor-activated receptor activity Hs molecular function 466 3.18e-140
macrophage colony-stimulating factor receptor activity Hs molecular function 331 3.41e-93
Ras guanyl-nucleotide exchange factor activity Hs molecular function 466 3.18e-140
protein binding Hs molecular function 466 3.18e-140
ATP binding Hs molecular function 466 3.18e-140
extracellular region Hs cellular component 466 3.18e-140
extracellular space Hs cellular component 242 1.53e-65
intracellular Hs cellular component 466 3.18e-140
cytoplasm Hs cellular component 242 1.53e-65
vacuole Hs cellular component 331 3.41e-93
plasma membrane Hs cellular component 466 3.18e-140
integral component of plasma membrane Hs cellular component 466 3.18e-140
basal plasma membrane Hs cellular component 466 3.18e-140
cell surface Hs cellular component 466 3.18e-140
membrane Hs cellular component 466 3.18e-140
integral component of membrane Hs cellular component 466 3.18e-140
rhabdomere Hs cellular component 242 1.53e-65
kinase activity Hs molecular function 466 3.18e-140
transferase activity Hs molecular function 466 3.18e-140
enzyme binding Hs molecular function 331 3.41e-93
protein phosphatase binding Hs molecular function 466 3.18e-140
identical protein binding Hs molecular function 466 3.18e-140
phosphatidylinositol-4,5-bisphosphate 3-kinase activity Hs molecular function 466 3.18e-140

GO (InterProScan)

5 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 1.5E-86
protein tyrosine kinase activity SMART molecular function 1.5E-124
protein binding Gene3D molecular function 3.2E-57
ATP binding ProSiteProfiles molecular function 35.637
protein phosphorylation SMART biological process 1.5E-124

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