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GENE CARD

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Gene Card

Best human hits

SMC2; SMC5; SMC6

Species

H.roretzi

Unique Gene ID

Harore.g00013932

Gene Model ID

Harore.CG.MTP2014.S241.g13932

Location

S241:48792..66524

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term Analysis Definition
SMC5 PANTHER Structural maintenance of chromosomes protein 5
P-loop_NTPase SUPERFAMILY P-loop containing nucleoside triphosphate hydrolase
RecF/RecN/SMC_N Pfam RecF/RecN/SMC, N-terminal

GOSlim

26 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
intracellular Blast cellular component
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
nucleolus Blast cellular component
cytoplasm Blast cellular component
cytosol Blast cellular component
DNA repair Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
cell cycle Orthology biological process
nuclear speck Orthology cellular component
cell junction Orthology cellular component
ubiquitin protein ligase binding Blast molecular function
protein heterodimerization activity Blast molecular function
cell division Orthology biological process
extracellular exosome Blast cellular component
organelle organization Orthology biological process
DNA metabolic process Orthology biological process
intracellular organelle part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear body Orthology cellular component
macromolecular complex Orthology cellular component
cellular response to stress Orthology biological process
nuclear lumen Blast cellular component

GO (Orthology)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
nucleotide binding Hs molecular function
telomere maintenance via recombination Hs biological process
double-strand break repair via homologous recombination Hs biological process
chromosome, telomeric region Hs cellular component
sex chromosome Hs cellular component
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
chromosome Hs cellular component
DNA repair Hs biological process
DNA recombination Hs biological process
cellular response to DNA damage stimulus Hs biological process
cell cycle Hs biological process
sister chromatid cohesion Hs biological process
PML body Hs cellular component
nuclear speck Hs cellular component
cell junction Hs cellular component
Smc5-Smc6 complex Hs cellular component
interchromatin granule Hs cellular component
site of double-strand break Hs cellular component
cell division Hs biological process
positive regulation of chromosome segregation Hs biological process
cellular senescence Hs biological process

GO (Blast)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 743 0.0
nuclear chromosome Hs cellular component 43.5 8.31e-04
chromosome, telomeric region Hs cellular component 743 0.0
condensed chromosome Hs cellular component 43.5 8.31e-04
condensin complex Hs cellular component 43.5 8.31e-04
sex chromosome Hs cellular component 743 0.0
protein binding Hs molecular function 743 0.0
ATP binding Hs molecular function 743 0.0
intracellular Hs cellular component 61.2 2.61e-09
nucleus Hs cellular component 743 0.0
nucleoplasm Hs cellular component 743 0.0
chromosome Hs cellular component 743 0.0
nucleolus Hs cellular component 43.5 8.31e-04
cytoplasm Hs cellular component 43.5 8.31e-04
cytosol Hs cellular component 43.5 8.31e-04
PML body Hs cellular component 743 0.0
nuclear speck Hs cellular component 743 0.0
cell junction Hs cellular component 743 0.0
Smc5-Smc6 complex Hs cellular component 743 0.0
ubiquitin protein ligase binding Hs molecular function 61.2 2.61e-09
interchromatin granule Hs cellular component 743 0.0
site of double-strand break Hs cellular component 743 0.0
protein heterodimerization activity Hs molecular function 43.5 8.31e-04
extracellular exosome Hs cellular component 43.5 8.31e-04

GO (InterProScan)

4 results

GO Term Analysis Type e-value
double-strand break repair via homologous recombination PANTHER biological process 0.0
DNA repair PANTHER biological process 0.0
sister chromatid cohesion PANTHER biological process 0.0
Smc5-Smc6 complex PANTHER cellular component 0.0