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Gene Card

Best human hits

KMT2A; KMT2B; KMT2D

Species

H.roretzi

Unique Gene ID

Harore.g00014487

Gene Model ID

Harore.CG.MTP2014.S208.g14487

Location

S208:45021..63095

Transcript Models and Sequences

  Harore.CG.MTP2014.S208.g14487.01.t
Harore.CG.MTP2014.S208.g14487.02.t
Harore.CG.MTP2014.S208.g14487.03.t
Harore.CG.MTP2014.S208.g14487.04.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
Bromodomain-like_sf Gene3D Bromodomain-like superfamily
Znf_RING/FYVE/PHD Gene3D Zinc finger, RING/FYVE/PHD-type
Znf_FYVE_PHD SUPERFAMILY Zinc finger, FYVE/PHD-type
FYrich_N Pfam FY-rich, N-terminal
FYrich_N SMART FY-rich, N-terminal
Znf_PHD-finger ProSiteProfiles Zinc finger, PHD-finger
Znf_PHD SMART Zinc finger, PHD-type
EPHD ProSiteProfiles Extended PHD (ePHD) domain
FYrich_N ProSiteProfiles FY-rich, N-terminal
Znf_PHD-finger Pfam Zinc finger, PHD-finger
Rcmb_RecR_CS ProSitePatterns Recombination protein RecR, conserved site

GOSlim

45 results

GO Term Annotation Origin Type
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
DNA binding Orthology molecular function
chromatin binding Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytosol Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
transcription from RNA polymerase II promoter Orthology biological process
apoptotic process Orthology biological process
zinc ion binding Orthology molecular function
negative regulation of cell proliferation Orthology biological process
regulation of gene expression Orthology biological process
transferase activity Orthology molecular function
identical protein binding Orthology molecular function
protein homodimerization activity Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
DNA repair InterProScan biological process
transcription regulatory region sequence-specific DNA binding Orthology molecular function
reproductive process Orthology biological process
animal organ development Orthology biological process
sequence-specific double-stranded DNA binding Orthology molecular function
DNA metabolic process Orthology biological process
organelle organization Orthology biological process
nervous system process Orthology biological process
metabolic process Orthology biological process
multicellular organism development Orthology biological process
cell development Orthology biological process
gamete generation Orthology biological process
negative regulation of gene expression Orthology biological process
cellular process Orthology biological process
cellular protein modification process Orthology biological process
nucleoplasm part Orthology cellular component
macromolecular complex Orthology cellular component
immune system process Orthology biological process
sequence-specific DNA binding Orthology molecular function
chemical synaptic transmission Orthology biological process
regulation of signaling Orthology biological process
regulation of cellular metabolic process Orthology biological process
cell differentiation Orthology biological process

GO (Orthology)

63 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
core promoter sequence-specific DNA binding Hs molecular function
ovarian follicle development Hs biological process
DNA binding Hs molecular function
AT DNA binding Hs molecular function
chromatin binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytosol Hs cellular component
DNA methylation Hs biological process
chromatin organization Hs biological process
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
transcription from RNA polymerase II promoter Hs biological process
apoptotic process Hs biological process
memory Hs biological process
methyltransferase activity Hs molecular function
zinc ion binding Hs molecular function
negative regulation of cell proliferation Hs biological process
visual learning Hs biological process
response to light stimulus Hs biological process
post-embryonic development Hs biological process
anterior/posterior pattern specification Hs biological process
oocyte differentiation Hs biological process
regulation of gene expression Hs biological process
gene silencing Hs biological process
transferase activity Hs molecular function
histone-lysine N-methyltransferase activity Hs molecular function
peptidyl-lysine monomethylation Hs biological process
ovulation Hs biological process
methylation Hs biological process
positive regulation of transporter activity Hs biological process
circadian regulation of gene expression Hs biological process
histone lysine methylation Hs biological process
histone methyltransferase complex Hs cellular component
embryonic hemopoiesis Hs biological process
histone methyltransferase activity (H3-K4 specific) Hs molecular function
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
histone H4-K16 acetylation Hs biological process
transcription regulatory region DNA binding Hs molecular function
histone H3-K4 dimethylation Hs biological process
unmethylated CpG binding Hs molecular function
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
metal ion binding Hs molecular function
chromatin-mediated maintenance of transcription Hs biological process
regulation of short-term neuronal synaptic plasticity Hs biological process
rhythmic process Hs biological process
homeostasis of number of cells within a tissue Hs biological process
cognition Hs biological process
histone H3-K4 methylation Hs biological process
regulation of histone H3-K4 methylation Hs biological process
positive regulation of histone H3-K4 methylation Hs biological process
membrane depolarization Hs biological process
definitive hemopoiesis Hs biological process
lysine-acetylated histone binding Hs molecular function
MLL1 complex Hs cellular component
histone H3-K4 trimethylation Hs biological process
regulation of hematopoietic stem cell differentiation Hs biological process
regulation of histone H3-K9 acetylation Hs biological process

GO (Blast)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 525 2.02e-149
core promoter sequence-specific DNA binding Hs molecular function 525 2.02e-149
DNA binding Hs molecular function 525 2.02e-149
AT DNA binding Hs molecular function 525 2.02e-149
chromatin binding Hs molecular function 525 2.02e-149
transcription factor activity, sequence-specific DNA binding Hs molecular function 525 2.02e-149
protein binding Hs molecular function 525 2.02e-149
nucleus Hs cellular component 525 2.02e-149
nucleoplasm Hs cellular component 525 2.02e-149
cytosol Hs cellular component 525 2.02e-149
methyltransferase activity Hs molecular function 525 2.02e-149
zinc ion binding Hs molecular function 525 2.02e-149
transferase activity Hs molecular function 525 2.02e-149
histone-lysine N-methyltransferase activity Hs molecular function 525 2.02e-149
histone methyltransferase complex Hs cellular component 525 2.02e-149
histone methyltransferase activity (H3-K4 specific) Hs molecular function 525 2.02e-149
identical protein binding Hs molecular function 525 2.02e-149
protein homodimerization activity Hs molecular function 525 2.02e-149
transcription regulatory region DNA binding Hs molecular function 525 2.02e-149
MLL3/4 complex Hs cellular component 157 1.35e-37
unmethylated CpG binding Hs molecular function 525 2.02e-149
metal ion binding Hs molecular function 525 2.02e-149
lysine-acetylated histone binding Hs molecular function 525 2.02e-149
MLL1 complex Hs cellular component 525 2.02e-149

GO (InterProScan)

4 results

GO Term Analysis Type e-value
protein binding Gene3D molecular function 4.5E-14
nucleus Pfam cellular component 6.5E-11
DNA repair ProSitePatterns biological process
DNA recombination ProSitePatterns biological process

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