Gene Card
Best human hits
SCN2A; SCN5A; SCN9A
Species
Unique Gene ID
Harore.g00014830
Gene Model ID
Harore.CG.MTP2014.S1.g14830
Location
S1:584913..612777
Transcript Models and Sequences
Harore.CG.MTP2014.S1.g14830.01.t
Harore.CG.MTP2014.S1.g14830.02.t
Harore.CG.MTP2014.S1.g14830.03.t
n/a
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IPR Term | Analysis | Definition |
---|---|---|
Na_channel_asu | PRINTS | Voltage gated sodium channel, alpha subunit |
Volt_channel_dom_sf | Gene3D | Voltage-dependent channel domain superfamily |
Ion_trans_dom | Pfam | Ion transport domain |
GO Term | Annotation Origin | Type |
---|---|---|
protein binding | Blast | molecular function |
calmodulin binding | Blast | molecular function |
intracellular | Blast | cellular component |
cytoplasm | Blast | cellular component |
endoplasmic reticulum | Blast | cellular component |
plasma membrane | Blast | cellular component |
integral component of plasma membrane | Blast | cellular component |
ion transport | Blast | biological process |
sodium ion transport | Blast | biological process |
cell surface | Blast | cellular component |
membrane | Blast | cellular component |
integral component of membrane | Blast | cellular component |
enzyme binding | Blast | molecular function |
protein kinase binding | Blast | molecular function |
axon | Blast | cellular component |
intrinsic component of plasma membrane | Blast | cellular component |
ubiquitin protein ligase binding | Blast | molecular function |
cell projection | Blast | cellular component |
perinuclear region of cytoplasm | Blast | cellular component |
transmembrane transport | Blast | biological process |
macromolecular complex | Blast | cellular component |
membrane raft | Blast | cellular component |
plasma membrane region | Blast | cellular component |
cell junction | Blast | cellular component |
plasma membrane part | Blast | cellular component |
organelle part | Blast | cellular component |
cytoplasmic part | Blast | cellular component |
intracellular non-membrane-bounded organelle | Blast | cellular component |
cytoskeletal protein binding | Blast | molecular function |
metal ion binding | Blast | molecular function |
cell projection part | Blast | cellular component |
cell-cell signaling | Blast | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
voltage-gated sodium channel complex | Hs | cellular component | 789 | 0.0 |
ion channel activity | Hs | molecular function | 789 | 0.0 |
voltage-gated ion channel activity | Hs | molecular function | 789 | 0.0 |
voltage-gated sodium channel activity | Hs | molecular function | 789 | 0.0 |
sodium channel activity | Hs | molecular function | 789 | 0.0 |
protein binding | Hs | molecular function | 789 | 0.0 |
calmodulin binding | Hs | molecular function | 789 | 0.0 |
intracellular | Hs | cellular component | 789 | 0.0 |
cytoplasm | Hs | cellular component | 789 | 0.0 |
endoplasmic reticulum | Hs | cellular component | 789 | 0.0 |
plasma membrane | Hs | cellular component | 789 | 0.0 |
integral component of plasma membrane | Hs | cellular component | 788 | 0.0 |
caveola | Hs | cellular component | 789 | 0.0 |
cell surface | Hs | cellular component | 789 | 0.0 |
intercalated disc | Hs | cellular component | 789 | 0.0 |
membrane | Hs | cellular component | 789 | 0.0 |
integral component of membrane | Hs | cellular component | 789 | 0.0 |
lateral plasma membrane | Hs | cellular component | 789 | 0.0 |
fibroblast growth factor binding | Hs | molecular function | 789 | 0.0 |
enzyme binding | Hs | molecular function | 789 | 0.0 |
protein kinase binding | Hs | molecular function | 789 | 0.0 |
protein domain specific binding | Hs | molecular function | 789 | 0.0 |
Z disc | Hs | cellular component | 789 | 0.0 |
T-tubule | Hs | cellular component | 789 | 0.0 |
axon | Hs | cellular component | 784 | 0.0 |
ankyrin binding | Hs | molecular function | 789 | 0.0 |
intrinsic component of plasma membrane | Hs | cellular component | 784 | 0.0 |
sodium ion binding | Hs | molecular function | 788 | 0.0 |
ubiquitin protein ligase binding | Hs | molecular function | 789 | 0.0 |
node of Ranvier | Hs | cellular component | 784 | 0.0 |
paranode region of axon | Hs | cellular component | 784 | 0.0 |
sodium channel complex | Hs | cellular component | 784 | 0.0 |
sarcolemma | Hs | cellular component | 789 | 0.0 |
cell projection | Hs | cellular component | 788 | 0.0 |
ion channel binding | Hs | molecular function | 789 | 0.0 |
perinuclear region of cytoplasm | Hs | cellular component | 789 | 0.0 |
nitric-oxide synthase binding | Hs | molecular function | 789 | 0.0 |
voltage-gated sodium channel activity involved in cardiac muscle cell action potential | Hs | molecular function | 789 | 0.0 |
voltage-gated sodium channel activity involved in AV node cell action potential | Hs | molecular function | 789 | 0.0 |
voltage-gated sodium channel activity involved in bundle of His cell action potential | Hs | molecular function | 789 | 0.0 |
voltage-gated sodium channel activity involved in Purkinje myocyte action potential | Hs | molecular function | 789 | 0.0 |
voltage-gated sodium channel activity involved in SA node cell action potential | Hs | molecular function | 789 | 0.0 |
scaffold protein binding | Hs | molecular function | 789 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
voltage-gated sodium channel complex | PRINTS | cellular component | 1.6E-11 |
ion channel activity | Pfam | molecular function | 6.0E-62 |
voltage-gated sodium channel activity | PRINTS | molecular function | 1.6E-11 |
ion transport | Pfam | biological process | 6.0E-62 |
sodium ion transport | PRINTS | biological process | 1.6E-11 |
membrane | Pfam | cellular component | 6.0E-62 |
transmembrane transport | Pfam | biological process | 6.0E-62 |