Gene Card
Best human hits
USP15; USP4; USP8
Species
Unique Gene ID
Moocci.g00025312
Gene Model ID
Moocci.CG.ELv1_2.S608320.g25312
Location
S608320:17981..42859
Transcript Models and Sequences
Moocci.CG.ELv1_2.S608320.g25312.01.t
Moocci.CG.ELv1_2.S608320.g25312.02.t
Moocci.CG.ELv1_2.S608320.g25312.03.t
n/a
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Click here to see the tree inference method
InterPro
12 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Rhodanese-like_dom_sf | SUPERFAMILY | Rhodanese-like domain superfamily |
| WW_dom | ProSiteProfiles | WW domain |
| USP_CS | ProSitePatterns | Ubiquitin specific protease, conserved site |
| USP_dom | ProSiteProfiles | Ubiquitin specific protease domain |
| USP8_dimer | Pfam | USP8 dimerisation domain |
| WW_dom | Pfam | WW domain |
| Rhodanese-like_dom | ProSiteProfiles | Rhodanese-like domain |
| WW_dom | CDD | WW domain |
| WW_dom | SMART | WW domain |
| Peptidase_C19_UCH | Pfam | Peptidase C19, ubiquitin carboxyl-terminal hydrolase |
| WW_dom_sf | SUPERFAMILY | WW domain superfamily |
| Rhodanese-like_dom_sf | Gene3D | Rhodanese-like domain superfamily |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
32 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| mitotic cytokinesis | Hs | biological process |
| cysteine-type endopeptidase activity | Hs | molecular function |
| thiol-dependent ubiquitin-specific protease activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| nucleus | Hs | cellular component |
| cytoplasm | Hs | cellular component |
| endosome | Hs | cellular component |
| early endosome | Hs | cellular component |
| cytosol | Hs | cellular component |
| plasma membrane | Hs | cellular component |
| proteolysis | Hs | biological process |
| ubiquitin-dependent protein catabolic process | Hs | biological process |
| endosome organization | Hs | biological process |
| cell cycle | Hs | biological process |
| peptidase activity | Hs | molecular function |
| cysteine-type peptidase activity | Hs | molecular function |
| cell proliferation | Hs | biological process |
| endosome membrane | Hs | cellular component |
| postsynaptic density | Hs | cellular component |
| membrane | Hs | cellular component |
| protein deubiquitination | Hs | biological process |
| hydrolase activity | Hs | molecular function |
| SH3 domain binding | Hs | molecular function |
| extrinsic component of plasma membrane | Hs | cellular component |
| midbody | Hs | cellular component |
| extrinsic component of endosome membrane | Hs | cellular component |
| thiol-dependent ubiquitinyl hydrolase activity | Hs | molecular function |
| dendritic spine | Hs | cellular component |
| cadherin binding | Hs | molecular function |
| protein K63-linked deubiquitination | Hs | biological process |
| protein K48-linked deubiquitination | Hs | biological process |
| positive regulation of canonical Wnt signaling pathway | Hs | biological process |
GO (Blast)
31 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| catalytic activity | Hs | molecular function | 212 | 3.17e-56 |
| cysteine-type endopeptidase activity | Hs | molecular function | 392 | 4.86e-117 |
| thiol-dependent ubiquitin-specific protease activity | Hs | molecular function | 392 | 4.86e-117 |
| transforming growth factor beta receptor binding | Hs | molecular function | 212 | 3.17e-56 |
| protein binding | Hs | molecular function | 392 | 4.86e-117 |
| nucleus | Hs | cellular component | 392 | 4.86e-117 |
| cytoplasm | Hs | cellular component | 392 | 4.86e-117 |
| mitochondrion | Hs | cellular component | 212 | 3.17e-56 |
| lysosome | Hs | cellular component | 212 | 3.03e-56 |
| endosome | Hs | cellular component | 392 | 4.86e-117 |
| early endosome | Hs | cellular component | 392 | 4.86e-117 |
| cytosol | Hs | cellular component | 392 | 4.86e-117 |
| plasma membrane | Hs | cellular component | 392 | 4.86e-117 |
| peptidase activity | Hs | molecular function | 392 | 4.86e-117 |
| cysteine-type peptidase activity | Hs | molecular function | 392 | 4.86e-117 |
| endosome membrane | Hs | cellular component | 392 | 4.86e-117 |
| postsynaptic density | Hs | cellular component | 392 | 4.86e-117 |
| membrane | Hs | cellular component | 392 | 4.86e-117 |
| hydrolase activity | Hs | molecular function | 392 | 4.86e-117 |
| SH3 domain binding | Hs | molecular function | 392 | 4.86e-117 |
| extrinsic component of plasma membrane | Hs | cellular component | 392 | 4.86e-117 |
| midbody | Hs | cellular component | 392 | 4.86e-117 |
| extrinsic component of endosome membrane | Hs | cellular component | 392 | 4.86e-117 |
| adenosine receptor binding | Hs | molecular function | 212 | 3.03e-56 |
| thiol-dependent ubiquitinyl hydrolase activity | Hs | molecular function | 392 | 4.86e-117 |
| identical protein binding | Hs | molecular function | 212 | 3.03e-56 |
| dendritic spine | Hs | cellular component | 392 | 4.86e-117 |
| cadherin binding | Hs | molecular function | 392 | 4.86e-117 |
| SMAD binding | Hs | molecular function | 212 | 3.17e-56 |
| metal ion binding | Hs | molecular function | 212 | 3.03e-56 |
| ubiquitin modification-dependent histone binding | Hs | molecular function | 212 | 3.17e-56 |
GO (InterProScan)
4 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein binding | SUPERFAMILY | molecular function | 5.4E-9 |
| ubiquitin-dependent protein catabolic process | ProSitePatterns | biological process | |
| protein deubiquitination | Pfam | biological process | 1.3E-52 |
| thiol-dependent ubiquitinyl hydrolase activity | Pfam | molecular function | 1.3E-52 |
