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GENE CARD

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Gene Card

Best human hits

NEDD4L; SMURF1; SMURF2

Species

M.oculata

Unique Gene ID

Moocul.g00012022

Gene Model ID

Moocul.CG.ELv1_2.S111456.g12022

Location

S111456:12620..22273

Transcript Models and Sequences

  Moocul.CG.ELv1_2.S111456.g12022.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

16 results

IPR Term Analysis Definition
WW_dom CDD WW domain
HECT_dom SMART HECT domain
C2_dom ProSiteProfiles C2 domain
WW_dom_sf SUPERFAMILY WW domain superfamily
WW_dom ProSiteProfiles WW domain
E3_ub_ligase_SMURF1 PIRSF E3 ubiquitin-protein ligase, SMURF1 type
WW_dom SMART WW domain
HECT_dom ProSiteProfiles HECT domain
WW_dom Pfam WW domain
Hect_E3_ubiquitin_ligase SUPERFAMILY HECT, E3 ligase catalytic domain
C2_dom Pfam C2 domain
C2_domain_sf Gene3D C2 domain superfamily
HECT_dom CDD HECT domain
HECT_dom Pfam HECT domain
WW_dom ProSitePatterns WW domain
C2_dom SMART C2 domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

49 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
ubiquitin ligase complex Hs cellular component
protein polyubiquitination Hs biological process
ubiquitin-protein transferase activity Hs molecular function
transforming growth factor beta receptor binding Hs molecular function
protein binding Hs molecular function
phospholipid binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
ubiquitin-dependent protein catabolic process Hs biological process
protein export from nucleus Hs biological process
transforming growth factor beta receptor signaling pathway Hs biological process
ectoderm development Hs biological process
membrane Hs cellular component
protein ubiquitination Hs biological process
protein deubiquitination Hs biological process
nuclear speck Hs cellular component
transferase activity Hs molecular function
regulation of transforming growth factor beta receptor signaling pathway Hs biological process
cell differentiation Hs biological process
negative regulation of ossification Hs biological process
axon Hs cellular component
BMP signaling pathway Hs biological process
negative regulation of transforming growth factor beta receptor signaling pathway Hs biological process
negative regulation of BMP signaling pathway Hs biological process
ubiquitin-dependent SMAD protein catabolic process Hs biological process
receptor catabolic process Hs biological process
protein localization to cell surface Hs biological process
identical protein binding Hs molecular function
neuronal cell body Hs cellular component
proteasome-mediated ubiquitin-dependent protein catabolic process Hs biological process
membrane raft Hs cellular component
negative regulation of transcription, DNA-templated Hs biological process
SMAD binding Hs molecular function
activin binding Hs molecular function
Wnt signaling pathway, planar cell polarity pathway Hs biological process
ubiquitin protein ligase activity Hs molecular function
extracellular exosome Hs cellular component
I-SMAD binding Hs molecular function
R-SMAD binding Hs molecular function
protein localization to plasma membrane Hs biological process
positive regulation of canonical Wnt signaling pathway Hs biological process
positive regulation of trophoblast cell migration Hs biological process
positive regulation of dendrite extension Hs biological process
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Hs biological process

GO (Blast)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
ubiquitin ligase complex Hs cellular component 1031 0.0
ubiquitin-protein transferase activity Hs molecular function 1031 0.0
transforming growth factor beta receptor binding Hs molecular function 1031 0.0
protein binding Hs molecular function 1031 0.0
phospholipid binding Hs molecular function 738 0.0
intracellular Hs cellular component 497 5.28e-163
nucleus Hs cellular component 1031 0.0
nucleoplasm Hs cellular component 1031 0.0
cytoplasm Hs cellular component 1031 0.0
mitochondrion Hs cellular component 738 0.0
endosome Hs cellular component 497 5.28e-163
multivesicular body Hs cellular component 497 5.28e-163
Golgi apparatus Hs cellular component 497 5.28e-163
cytosol Hs cellular component 1031 0.0
plasma membrane Hs cellular component 1031 0.0
potassium channel regulator activity Hs molecular function 497 5.28e-163
membrane Hs cellular component 1031 0.0
nuclear speck Hs cellular component 1031 0.0
transferase activity Hs molecular function 1031 0.0
sodium channel regulator activity Hs molecular function 497 5.28e-163
potassium channel inhibitor activity Hs molecular function 497 5.28e-163
sodium channel inhibitor activity Hs molecular function 497 5.28e-163
axon Hs cellular component 738 0.0
identical protein binding Hs molecular function 1031 0.0
neuronal cell body Hs cellular component 738 0.0
ion channel binding Hs molecular function 497 5.28e-163
membrane raft Hs cellular component 1031 0.0
SMAD binding Hs molecular function 1031 0.0
activin binding Hs molecular function 738 0.0
ubiquitin protein ligase activity Hs molecular function 1031 0.0
extracellular exosome Hs cellular component 738 0.0
I-SMAD binding Hs molecular function 738 0.0
R-SMAD binding Hs molecular function 738 0.0

GO (InterProScan)

4 results

GO Term Analysis Type e-value
ubiquitin-protein transferase activity CDD molecular function 6.3213E-161
protein binding Pfam molecular function 7.7E-12
ubiquitin-dependent protein catabolic process PIRSF biological process 1.7E-201
ubiquitin protein ligase activity PIRSF molecular function 1.7E-201

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