Gene Card
Best human hits
DARS; DARS2; KARS
Species
Unique Gene ID
Phfumi.g00000064
Gene Model ID
Phfumi.CG.MTP2014.S2.g00064
Location
S2:428330..432652
Transcript Models and Sequences
Phfumi.CG.MTP2014.S2.g00064.01.t
Phfumi.CG.MTP2014.S2.g00064.02.t
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Lys-tRNA-ligase_II_bac/euk | PIRSF | Bacterial/eukaryotic lysine-tRNA ligase, class II |
Lys-tRNA-synth_II_C | CDD | Lysyl-tRNA synthetase, class II, C-terminal |
Lys-tRNA-ligase_II | Hamap | Lysine-tRNA ligase, class II |
Lys-tRNA-ligase_II | TIGRFAM | Lysine-tRNA ligase, class II |
aa-tRNA-synth_II | ProSiteProfiles | Aminoacyl-tRNA synthetase, class II |
aa-tRNA-synt_II | Pfam | Aminoacyl-tRNA synthetase, class II (D/K/N) |
NA-bd_OB-fold | SUPERFAMILY | Nucleic acid-binding, OB-fold |
Lys-tRNA-synth_II_C | PRINTS | Lysyl-tRNA synthetase, class II, C-terminal |
NA-bd_OB_tRNA | Pfam | OB-fold nucleic acid binding domain, AA-tRNA synthetase-type |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
nucleic acid binding | Orthology | molecular function |
RNA binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
extracellular region | Orthology | cellular component |
extracellular space | Orthology | cellular component |
nucleus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
mitochondrial matrix | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
negative regulation of cell proliferation | Orthology | biological process |
membrane | Orthology | cellular component |
transferase activity | Orthology | molecular function |
ligase activity | Orthology | molecular function |
identical protein binding | Orthology | molecular function |
protein homodimerization activity | Orthology | molecular function |
positive regulation of transcription, DNA-templated | Orthology | biological process |
extracellular exosome | Blast | cellular component |
positive regulation of catalytic activity | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
protein serine/threonine kinase activity | Orthology | molecular function |
positive regulation of signal transduction | Orthology | biological process |
transferase activity, transferring phosphorus-containing groups | Orthology | molecular function |
RNA metabolic process | Orthology | biological process |
RNA processing | Orthology | biological process |
phosphate-containing compound metabolic process | Orthology | biological process |
small molecule binding | Orthology | molecular function |
anion binding | Orthology | molecular function |
intracellular part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
cytokine-mediated signaling pathway | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
cellular response to stress | Orthology | biological process |
metallopeptidase activity | Orthology | molecular function |
positive regulation of hydrolase activity | Orthology | biological process |
hydrolase activity | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
tRNA binding | Hs | molecular function |
nucleotide binding | Hs | molecular function |
activation of MAPK activity | Hs | biological process |
nucleic acid binding | Hs | molecular function |
ATP adenylyltransferase activity | Hs | molecular function |
aminoacyl-tRNA ligase activity | Hs | molecular function |
lysine-tRNA ligase activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
extracellular region | Hs | cellular component |
extracellular space | Hs | cellular component |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
mitochondrion | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
translation | Hs | biological process |
tRNA aminoacylation for protein translation | Hs | biological process |
lysyl-tRNA aminoacylation | Hs | biological process |
tRNA processing | Hs | biological process |
negative regulation of cell proliferation | Hs | biological process |
response to X-ray | Hs | biological process |
diadenosine tetraphosphate biosynthetic process | Hs | biological process |
membrane | Hs | cellular component |
viral process | Hs | biological process |
amino acid binding | Hs | molecular function |
transferase activity | Hs | molecular function |
ligase activity | Hs | molecular function |
aminoacyl-tRNA synthetase multienzyme complex | Hs | cellular component |
tumor necrosis factor-mediated signaling pathway | Hs | biological process |
identical protein binding | Hs | molecular function |
protein homodimerization activity | Hs | molecular function |
positive regulation of transcription, DNA-templated | Hs | biological process |
positive regulation of ERK1 and ERK2 cascade | Hs | biological process |
positive regulation of p38MAPK cascade | Hs | biological process |
positive regulation of metallopeptidase activity | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
tRNA binding | Hs | molecular function | 831 | 0.0 |
nucleotide binding | Hs | molecular function | 831 | 0.0 |
nucleic acid binding | Hs | molecular function | 831 | 0.0 |
RNA binding | Hs | molecular function | 72.8 | 1.95e-13 |
ATP adenylyltransferase activity | Hs | molecular function | 831 | 0.0 |
aminoacylase activity | Hs | molecular function | 72.8 | 1.95e-13 |
aminoacyl-tRNA ligase activity | Hs | molecular function | 831 | 0.0 |
aspartate-tRNA ligase activity | Hs | molecular function | 79.7 | 1.32e-15 |
lysine-tRNA ligase activity | Hs | molecular function | 831 | 0.0 |
protein binding | Hs | molecular function | 831 | 0.0 |
ATP binding | Hs | molecular function | 831 | 0.0 |
extracellular region | Hs | cellular component | 831 | 0.0 |
extracellular space | Hs | cellular component | 831 | 0.0 |
nucleus | Hs | cellular component | 831 | 0.0 |
cytoplasm | Hs | cellular component | 831 | 0.0 |
mitochondrion | Hs | cellular component | 831 | 0.0 |
mitochondrial matrix | Hs | cellular component | 831 | 0.0 |
cytosol | Hs | cellular component | 831 | 0.0 |
plasma membrane | Hs | cellular component | 831 | 0.0 |
membrane | Hs | cellular component | 831 | 0.0 |
amino acid binding | Hs | molecular function | 831 | 0.0 |
transferase activity | Hs | molecular function | 831 | 0.0 |
ligase activity | Hs | molecular function | 831 | 0.0 |
aminoacyl-tRNA synthetase multienzyme complex | Hs | cellular component | 831 | 0.0 |
identical protein binding | Hs | molecular function | 831 | 0.0 |
protein homodimerization activity | Hs | molecular function | 831 | 0.0 |
aspartate-tRNA(Asn) ligase activity | Hs | molecular function | 79.7 | 1.32e-15 |
extracellular exosome | Hs | cellular component | 72.8 | 1.95e-13 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
nucleotide binding | CDD | molecular function | 0.0 |
nucleic acid binding | Pfam | molecular function | 5.4E-11 |
aminoacyl-tRNA ligase activity | Pfam | molecular function | 5.2E-82 |
lysine-tRNA ligase activity | CDD | molecular function | 0.0 |
ATP binding | CDD | molecular function | 0.0 |
cytoplasm | CDD | cellular component | 0.0 |
tRNA aminoacylation for protein translation | Pfam | biological process | 5.2E-82 |
lysyl-tRNA aminoacylation | CDD | biological process | 0.0 |