Gene Card
Best human hits
PRKACA; PRKG1; PRKG2
Species
Unique Gene ID
Phfumi.g00000071
Gene Model ID
Phfumi.CG.MTP2014.S3.g00071
Location
S3:119196..123257
Transcript Models and Sequences
n/a
You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see how you can interact with this tree
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
cGMP_dep_kinase | PRINTS | cGMP-dependent kinase |
Prot_kinase_dom | Pfam | Protein kinase domain |
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
Prot_kinase_dom | SMART | Protein kinase domain |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
STKc_cGK | CDD | cGMP-dependent protein kinase, catalytic domain |
AGC-kinase_C | SMART | AGC-kinase, C-terminal |
AGC-kinase_C | ProSiteProfiles | AGC-kinase, C-terminal |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
cNMP-bd_dom | ProSiteProfiles | Cyclic nucleotide-binding domain |
RmlC-like_jellyroll | Gene3D | RmlC-like jelly roll fold |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
magnesium ion binding | Blast | molecular function |
catalytic activity | Orthology | molecular function |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
nucleus | Blast | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Blast | cellular component |
Golgi apparatus | Orthology | cellular component |
centrosome | Blast | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
protein phosphorylation | Orthology | biological process |
signal transduction | Orthology | biological process |
metabolic process | Orthology | biological process |
membrane | Blast | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
apical plasma membrane | Blast | cellular component |
nuclear speck | Blast | cellular component |
transferase activity | Orthology | molecular function |
protein kinase binding | Blast | molecular function |
cytoplasmic vesicle | Blast | cellular component |
ubiquitin protein ligase binding | Blast | molecular function |
nuclear membrane | Blast | cellular component |
protein homodimerization activity | Blast | molecular function |
cell projection | Blast | cellular component |
regulation of GTPase activity | Orthology | biological process |
perinuclear region of cytoplasm | Blast | cellular component |
extracellular exosome | Blast | cellular component |
cell migration | Orthology | biological process |
generation of neurons | Orthology | biological process |
molecular transducer activity | Orthology | molecular function |
molecular function regulator | Orthology | molecular function |
transmembrane transport | Orthology | biological process |
neuron projection development | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
organelle organization | Orthology | biological process |
anion binding | Orthology | molecular function |
guanyl ribonucleotide binding | Orthology | molecular function |
brain development | Orthology | biological process |
endomembrane system | Blast | cellular component |
organelle | Blast | cellular component |
plasma membrane region | Blast | cellular component |
macromolecular complex | Blast | cellular component |
cell projection part | Blast | cellular component |
microtubule | Blast | cellular component |
cytoplasmic part | Blast | cellular component |
intracellular part | Blast | cellular component |
transition metal ion binding | Blast | molecular function |
synapse | Blast | cellular component |
integral component of membrane | Blast | cellular component |
postsynapse | Blast | cellular component |
membrane raft | Blast | cellular component |
extracellular region part | Blast | cellular component |
organelle part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
neuron migration | Hs | biological process |
catalytic activity | Hs | molecular function |
protein kinase activity | Hs | molecular function |
protein serine/threonine kinase activity | Hs | molecular function |
cGMP-dependent protein kinase activity | Hs | molecular function |
calcium channel regulator activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
Golgi apparatus | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
protein phosphorylation | Hs | biological process |
signal transduction | Hs | biological process |
metabolic process | Hs | biological process |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
dendrite development | Hs | biological process |
transferase activity | Hs | molecular function |
cGMP-mediated signaling | Hs | biological process |
actin cytoskeleton organization | Hs | biological process |
cGMP binding | Hs | molecular function |
forebrain development | Hs | biological process |
regulation of GTPase activity | Hs | biological process |
negative regulation of smooth muscle contraction | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 580 | 0.0 |
magnesium ion binding | Hs | molecular function | 286 | 6.72e-95 |
acrosomal vesicle | Hs | cellular component | 286 | 6.72e-95 |
catalytic activity | Hs | molecular function | 580 | 0.0 |
protein kinase activity | Hs | molecular function | 580 | 0.0 |
protein serine/threonine kinase activity | Hs | molecular function | 580 | 0.0 |
cAMP-dependent protein kinase activity | Hs | molecular function | 286 | 6.72e-95 |
cGMP-dependent protein kinase activity | Hs | molecular function | 580 | 0.0 |
protein serine/threonine/tyrosine kinase activity | Hs | molecular function | 286 | 6.72e-95 |
calcium channel regulator activity | Hs | molecular function | 580 | 0.0 |
protein binding | Hs | molecular function | 580 | 0.0 |
ATP binding | Hs | molecular function | 580 | 0.0 |
nucleus | Hs | cellular component | 286 | 6.72e-95 |
nucleoplasm | Hs | cellular component | 286 | 6.72e-95 |
cytoplasm | Hs | cellular component | 580 | 0.0 |
mitochondrion | Hs | cellular component | 286 | 6.72e-95 |
Golgi apparatus | Hs | cellular component | 580 | 0.0 |
centrosome | Hs | cellular component | 286 | 6.72e-95 |
cytosol | Hs | cellular component | 580 | 0.0 |
plasma membrane | Hs | cellular component | 580 | 0.0 |
cilium | Hs | cellular component | 286 | 6.72e-95 |
axoneme | Hs | cellular component | 286 | 6.72e-95 |
cAMP-dependent protein kinase complex | Hs | cellular component | 286 | 6.72e-95 |
membrane | Hs | cellular component | 468 | 1.58e-160 |
kinase activity | Hs | molecular function | 580 | 0.0 |
apical plasma membrane | Hs | cellular component | 468 | 1.58e-160 |
nuclear speck | Hs | cellular component | 286 | 6.72e-95 |
transferase activity | Hs | molecular function | 580 | 0.0 |
protein kinase binding | Hs | molecular function | 286 | 6.72e-95 |
protein domain specific binding | Hs | molecular function | 286 | 6.72e-95 |
manganese ion binding | Hs | molecular function | 286 | 6.72e-95 |
cGMP binding | Hs | molecular function | 580 | 0.0 |
cytoplasmic vesicle | Hs | cellular component | 286 | 6.72e-95 |
motile cilium | Hs | cellular component | 286 | 6.72e-95 |
neuromuscular junction | Hs | cellular component | 286 | 6.72e-95 |
ubiquitin protein ligase binding | Hs | molecular function | 286 | 6.72e-95 |
nuclear membrane | Hs | cellular component | 468 | 1.58e-160 |
protein kinase A regulatory subunit binding | Hs | molecular function | 286 | 6.72e-95 |
calcium channel complex | Hs | cellular component | 286 | 6.72e-95 |
sperm flagellum | Hs | cellular component | 286 | 6.72e-95 |
protein homodimerization activity | Hs | molecular function | 468 | 1.58e-160 |
cell projection | Hs | cellular component | 286 | 6.72e-95 |
dendritic spine | Hs | cellular component | 286 | 6.72e-95 |
plasma membrane raft | Hs | cellular component | 286 | 6.72e-95 |
intercellular bridge | Hs | cellular component | 286 | 6.72e-95 |
perinuclear region of cytoplasm | Hs | cellular component | 286 | 6.72e-95 |
extracellular exosome | Hs | cellular component | 286 | 6.72e-95 |
ciliary base | Hs | cellular component | 286 | 6.72e-95 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | SMART | molecular function | 6.7E-89 |
protein serine/threonine kinase activity | SMART | molecular function | 9.7E-7 |
cGMP-dependent protein kinase activity | CDD | molecular function | 0.0 |
ATP binding | SMART | molecular function | 6.7E-89 |
protein phosphorylation | SMART | biological process | 6.7E-89 |