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GENE CARD

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Gene Card

Best human hits

EXD2; EXD3; WRN

Species

P.fumigata

Unique Gene ID

Phfumi.g00000086

Gene Model ID

Phfumi.CG.MTP2014.S4.g00086

Location

S4:28372..29014

Transcript Models and Sequences

  Phfumi.CG.MTP2014.S4.g00086.01.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term Analysis Definition
RNaseH-like_sf SUPERFAMILY Ribonuclease H-like superfamily
RNaseH_sf Gene3D Ribonuclease H superfamily
3'-5'_exonuclease_dom SMART 3'-5' exonuclease domain
3'-5'_exonuclease_dom Pfam 3'-5' exonuclease domain

GOSlim

30 results

GO Term Annotation Origin Type
nucleotide binding Blast molecular function
magnesium ion binding Blast molecular function
nucleic acid binding Blast molecular function
DNA binding Blast molecular function
chromatin binding Blast molecular function
catalytic activity Blast molecular function
protein binding Blast molecular function
ATP binding Blast molecular function
intracellular Blast cellular component
nucleus Blast cellular component
nucleoplasm Blast cellular component
nucleolus Blast cellular component
cytoplasm Blast cellular component
centrosome Blast cellular component
nucleobase-containing compound metabolic process InterProScan biological process
DNA metabolic process Blast biological process
nuclear speck Blast cellular component
hydrolase activity Blast molecular function
protein homodimerization activity Blast molecular function
neuron projection Blast cellular component
macromolecular complex binding Blast molecular function
metal ion binding Blast molecular function
intracellular organelle part Blast cellular component
intracellular non-membrane-bounded organelle Blast cellular component
organelle organization Blast biological process
nucleoside-triphosphatase activity Blast molecular function
transition metal ion binding Blast molecular function
nuclear part Blast cellular component
macromolecular complex Blast cellular component
sequence-specific DNA binding Blast molecular function

GO (Orthology)

No result

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type

GO (Blast)

46 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 155 1.35e-43
magnesium ion binding Hs molecular function 155 1.35e-43
four-way junction DNA binding Hs molecular function 155 1.35e-43
Y-form DNA binding Hs molecular function 155 1.35e-43
bubble DNA binding Hs molecular function 155 1.35e-43
chromosome, telomeric region Hs cellular component 155 1.35e-43
nucleic acid binding Hs molecular function 155 1.35e-43
DNA binding Hs molecular function 155 1.35e-43
DNA helicase activity Hs molecular function 155 1.35e-43
chromatin binding Hs molecular function 155 1.35e-43
catalytic activity Hs molecular function 155 1.35e-43
ATP-dependent DNA helicase activity Hs molecular function 155 1.35e-43
helicase activity Hs molecular function 155 1.35e-43
nuclease activity Hs molecular function 155 1.35e-43
exonuclease activity Hs molecular function 155 1.35e-43
protein binding Hs molecular function 155 1.35e-43
ATP binding Hs molecular function 155 1.35e-43
intracellular Hs cellular component 155 1.35e-43
nucleus Hs cellular component 155 1.35e-43
nucleoplasm Hs cellular component 155 1.35e-43
replication fork Hs cellular component 155 1.35e-43
nucleolus Hs cellular component 155 1.35e-43
cytoplasm Hs cellular component 155 1.35e-43
centrosome Hs cellular component 155 1.35e-43
ATP-dependent helicase activity Hs molecular function 155 1.35e-43
single-stranded DNA 3'-5' exodeoxyribonuclease activity Hs molecular function 57.4 1.07e-09
3'-5' exonuclease activity Hs molecular function 155 1.35e-43
exodeoxyribonuclease I activity Hs molecular function 57.4 1.07e-09
four-way junction helicase activity Hs molecular function 155 1.35e-43
nuclear speck Hs cellular component 155 1.35e-43
hydrolase activity Hs molecular function 155 1.35e-43
ATPase activity Hs molecular function 155 1.35e-43
manganese ion binding Hs molecular function 155 1.35e-43
MutLalpha complex Hs cellular component 155 1.35e-43
protein homodimerization activity Hs molecular function 155 1.35e-43
neuron projection Hs cellular component 155 1.35e-43
3'-5' DNA helicase activity Hs molecular function 155 1.35e-43
ATP-dependent 3'-5' DNA helicase activity Hs molecular function 155 1.35e-43
macromolecular complex binding Hs molecular function 155 1.35e-43
metal ion binding Hs molecular function 155 1.35e-43
G-quadruplex DNA binding Hs molecular function 155 1.35e-43
forked DNA-dependent helicase activity Hs molecular function 155 1.35e-43
telomeric D-loop binding Hs molecular function 155 1.35e-43
telomeric G-quadruplex DNA binding Hs molecular function 155 1.35e-43
3'-flap-structured DNA binding Hs molecular function 155 1.35e-43
8-hydroxy-2'-deoxyguanosine DNA binding Hs molecular function 155 1.35e-43

GO (InterProScan)

3 results

GO Term Analysis Type e-value
nucleic acid binding Gene3D molecular function 2.2E-57
nucleobase-containing compound metabolic process Pfam biological process 1.5E-25
3'-5' exonuclease activity Pfam molecular function 1.5E-25