Gene Card
Best human hits
EXD2; EXD3; WRN
Species
Unique Gene ID
Phfumi.g00000086
Gene Model ID
Phfumi.CG.MTP2014.S4.g00086
Location
S4:28372..29014
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
RNaseH-like_sf | SUPERFAMILY | Ribonuclease H-like superfamily |
RNaseH_sf | Gene3D | Ribonuclease H superfamily |
3'-5'_exonuclease_dom | SMART | 3'-5' exonuclease domain |
3'-5'_exonuclease_dom | Pfam | 3'-5' exonuclease domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Blast | molecular function |
magnesium ion binding | Blast | molecular function |
nucleic acid binding | Blast | molecular function |
DNA binding | Blast | molecular function |
chromatin binding | Blast | molecular function |
catalytic activity | Blast | molecular function |
protein binding | Blast | molecular function |
ATP binding | Blast | molecular function |
intracellular | Blast | cellular component |
nucleus | Blast | cellular component |
nucleoplasm | Blast | cellular component |
nucleolus | Blast | cellular component |
cytoplasm | Blast | cellular component |
centrosome | Blast | cellular component |
nucleobase-containing compound metabolic process | InterProScan | biological process |
DNA metabolic process | Blast | biological process |
nuclear speck | Blast | cellular component |
hydrolase activity | Blast | molecular function |
protein homodimerization activity | Blast | molecular function |
neuron projection | Blast | cellular component |
macromolecular complex binding | Blast | molecular function |
metal ion binding | Blast | molecular function |
intracellular organelle part | Blast | cellular component |
intracellular non-membrane-bounded organelle | Blast | cellular component |
organelle organization | Blast | biological process |
nucleoside-triphosphatase activity | Blast | molecular function |
transition metal ion binding | Blast | molecular function |
nuclear part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
sequence-specific DNA binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 155 | 1.35e-43 |
magnesium ion binding | Hs | molecular function | 155 | 1.35e-43 |
four-way junction DNA binding | Hs | molecular function | 155 | 1.35e-43 |
Y-form DNA binding | Hs | molecular function | 155 | 1.35e-43 |
bubble DNA binding | Hs | molecular function | 155 | 1.35e-43 |
chromosome, telomeric region | Hs | cellular component | 155 | 1.35e-43 |
nucleic acid binding | Hs | molecular function | 155 | 1.35e-43 |
DNA binding | Hs | molecular function | 155 | 1.35e-43 |
DNA helicase activity | Hs | molecular function | 155 | 1.35e-43 |
chromatin binding | Hs | molecular function | 155 | 1.35e-43 |
catalytic activity | Hs | molecular function | 155 | 1.35e-43 |
ATP-dependent DNA helicase activity | Hs | molecular function | 155 | 1.35e-43 |
helicase activity | Hs | molecular function | 155 | 1.35e-43 |
nuclease activity | Hs | molecular function | 155 | 1.35e-43 |
exonuclease activity | Hs | molecular function | 155 | 1.35e-43 |
protein binding | Hs | molecular function | 155 | 1.35e-43 |
ATP binding | Hs | molecular function | 155 | 1.35e-43 |
intracellular | Hs | cellular component | 155 | 1.35e-43 |
nucleus | Hs | cellular component | 155 | 1.35e-43 |
nucleoplasm | Hs | cellular component | 155 | 1.35e-43 |
replication fork | Hs | cellular component | 155 | 1.35e-43 |
nucleolus | Hs | cellular component | 155 | 1.35e-43 |
cytoplasm | Hs | cellular component | 155 | 1.35e-43 |
centrosome | Hs | cellular component | 155 | 1.35e-43 |
ATP-dependent helicase activity | Hs | molecular function | 155 | 1.35e-43 |
single-stranded DNA 3'-5' exodeoxyribonuclease activity | Hs | molecular function | 57.4 | 1.07e-09 |
3'-5' exonuclease activity | Hs | molecular function | 155 | 1.35e-43 |
exodeoxyribonuclease I activity | Hs | molecular function | 57.4 | 1.07e-09 |
four-way junction helicase activity | Hs | molecular function | 155 | 1.35e-43 |
nuclear speck | Hs | cellular component | 155 | 1.35e-43 |
hydrolase activity | Hs | molecular function | 155 | 1.35e-43 |
ATPase activity | Hs | molecular function | 155 | 1.35e-43 |
manganese ion binding | Hs | molecular function | 155 | 1.35e-43 |
MutLalpha complex | Hs | cellular component | 155 | 1.35e-43 |
protein homodimerization activity | Hs | molecular function | 155 | 1.35e-43 |
neuron projection | Hs | cellular component | 155 | 1.35e-43 |
3'-5' DNA helicase activity | Hs | molecular function | 155 | 1.35e-43 |
ATP-dependent 3'-5' DNA helicase activity | Hs | molecular function | 155 | 1.35e-43 |
macromolecular complex binding | Hs | molecular function | 155 | 1.35e-43 |
metal ion binding | Hs | molecular function | 155 | 1.35e-43 |
G-quadruplex DNA binding | Hs | molecular function | 155 | 1.35e-43 |
forked DNA-dependent helicase activity | Hs | molecular function | 155 | 1.35e-43 |
telomeric D-loop binding | Hs | molecular function | 155 | 1.35e-43 |
telomeric G-quadruplex DNA binding | Hs | molecular function | 155 | 1.35e-43 |
3'-flap-structured DNA binding | Hs | molecular function | 155 | 1.35e-43 |
8-hydroxy-2'-deoxyguanosine DNA binding | Hs | molecular function | 155 | 1.35e-43 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
nucleic acid binding | Gene3D | molecular function | 2.2E-57 |
nucleobase-containing compound metabolic process | Pfam | biological process | 1.5E-25 |
3'-5' exonuclease activity | Pfam | molecular function | 1.5E-25 |