Gene Card
Best human hits
CRK; CRKL; GRAP
Species
Unique Gene ID
Phfumi.g00001041
Gene Model ID
Phfumi.CG.MTP2014.S113.g01041
Location
S113:40073..41676
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
SH3_domain | ProSiteProfiles | SH3 domain |
SH2 | SMART | SH2 domain |
SH2 | Pfam | SH2 domain |
SH2_dom_sf | SUPERFAMILY | SH2 domain superfamily |
SH3_domain | Pfam | SH3 domain |
SH3_domain | SMART | SH3 domain |
SH2 | ProSiteProfiles | SH2 domain |
SH3_domain | PRINTS | SH3 domain |
CRK_SH3_N | CDD | CRK, N-terminal SH3 domain |
SH2 | PRINTS | SH2 domain |
SH3-like_dom_sf | SUPERFAMILY | SH3-like domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
blood vessel development | Orthology | biological process |
RNA binding | Orthology | molecular function |
signal transducer activity | Orthology | molecular function |
receptor binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
endosome | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
heart development | Orthology | biological process |
cytoskeletal protein binding | Orthology | molecular function |
positive regulation of cell proliferation | Orthology | biological process |
regulation of signal transduction | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
membrane | Orthology | cellular component |
cytokine-mediated signaling pathway | Orthology | biological process |
enzyme binding | Orthology | molecular function |
macromolecular complex | Orthology | cellular component |
intracellular signal transduction | Orthology | biological process |
identical protein binding | Orthology | molecular function |
regulation of GTPase activity | Orthology | biological process |
membrane raft | Orthology | cellular component |
extracellular exosome | Orthology | cellular component |
positive regulation of catalytic activity | Orthology | biological process |
protein serine/threonine kinase activity | Orthology | molecular function |
cellular response to stress | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
small GTPase mediated signal transduction | Orthology | biological process |
multicellular organism development | Orthology | biological process |
cell morphogenesis | Orthology | biological process |
animal organ development | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
cytoskeleton | Orthology | cellular component |
organelle organization | Orthology | biological process |
response to oxidative stress | Orthology | biological process |
regulation of molecular function | Orthology | biological process |
cell adhesion molecule binding | Orthology | molecular function |
cell surface receptor signaling pathway | Orthology | biological process |
immune system process | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
cell morphogenesis involved in differentiation | Orthology | biological process |
cell adhesion | Orthology | biological process |
response to organic substance | Orthology | biological process |
protein kinase binding | Orthology | molecular function |
cell motility | Orthology | biological process |
protein kinase activity | Blast | molecular function |
intracellular part | Blast | cellular component |
plasma membrane part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
phosphotyrosine residue binding | Hs | molecular function | 273 | 1.36e-91 |
RNA binding | Hs | molecular function | 273 | 1.36e-91 |
non-membrane spanning protein tyrosine kinase activity | Hs | molecular function | 97.4 | 2.27e-24 |
signal transducer activity | Hs | molecular function | 273 | 1.36e-91 |
SH3/SH2 adaptor activity | Hs | molecular function | 273 | 1.36e-91 |
receptor binding | Hs | molecular function | 97.4 | 2.27e-24 |
insulin-like growth factor receptor binding | Hs | molecular function | 257 | 2.68e-85 |
protein binding | Hs | molecular function | 273 | 1.36e-91 |
nucleus | Hs | cellular component | 257 | 2.68e-85 |
nucleoplasm | Hs | cellular component | 273 | 1.36e-91 |
cytoplasm | Hs | cellular component | 273 | 1.36e-91 |
endosome | Hs | cellular component | 273 | 1.36e-91 |
cytosol | Hs | cellular component | 273 | 1.36e-91 |
plasma membrane | Hs | cellular component | 257 | 2.68e-85 |
cytoskeletal protein binding | Hs | molecular function | 257 | 2.68e-85 |
actin cytoskeleton | Hs | cellular component | 257 | 2.68e-85 |
membrane | Hs | cellular component | 257 | 2.68e-85 |
SH3 domain binding | Hs | molecular function | 257 | 2.68e-85 |
enzyme binding | Hs | molecular function | 257 | 2.68e-85 |
protein domain specific binding | Hs | molecular function | 257 | 2.68e-85 |
protein binding, bridging | Hs | molecular function | 257 | 2.68e-85 |
extrinsic component of cytoplasmic side of plasma membrane | Hs | cellular component | 97.4 | 2.27e-24 |
macromolecular complex | Hs | cellular component | 257 | 2.68e-85 |
SH2 domain binding | Hs | molecular function | 257 | 2.68e-85 |
identical protein binding | Hs | molecular function | 273 | 1.36e-91 |
protein self-association | Hs | molecular function | 257 | 2.68e-85 |
membrane raft | Hs | cellular component | 257 | 2.68e-85 |
cadherin binding | Hs | molecular function | 273 | 1.36e-91 |
protein phosphorylated amino acid binding | Hs | molecular function | 257 | 2.68e-85 |
ephrin receptor binding | Hs | molecular function | 257 | 2.68e-85 |
extracellular exosome | Hs | cellular component | 273 | 1.36e-91 |
scaffold protein binding | Hs | molecular function | 257 | 2.68e-85 |
protein tyrosine kinase binding | Hs | molecular function | 257 | 2.68e-85 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein binding | SUPERFAMILY | molecular function | 1.71E-21 |