Gene Card
Best human hits
GRK4; GRK5; GRK6
Species
Unique Gene ID
Phfumi.g00006630
Gene Model ID
Phfumi.CG.MTP2014.S4914.g06630
Location
S4914:1533..12482
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Prot_kinase_dom | SMART | Protein kinase domain |
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Prot_kinase_dom | Pfam | Protein kinase domain |
RGS | ProSiteProfiles | RGS domain |
RGS_sf | SUPERFAMILY | RGS domain superfamily |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
GPCR_kinase | PRINTS | GPCR kinase |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
protein phosphorylation | Orthology | biological process |
apoptotic process | Orthology | biological process |
signal transduction | Orthology | biological process |
G-protein coupled receptor signaling pathway | Orthology | biological process |
positive regulation of cell proliferation | Orthology | biological process |
membrane | Orthology | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
nuclear speck | Orthology | cellular component |
transferase activity | Orthology | molecular function |
nuclear membrane | Orthology | cellular component |
neuronal cell body | Orthology | cellular component |
negative regulation of apoptotic process | Orthology | biological process |
protein autophosphorylation | Orthology | biological process |
protein kinase binding | Orthology | molecular function |
anion binding | Orthology | molecular function |
cell periphery | Orthology | cellular component |
cytoplasmic part | Orthology | cellular component |
regulation of catalytic activity | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
regulation of signal transduction | Orthology | biological process |
binding | Orthology | molecular function |
cell surface receptor signaling pathway | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
membrane organization | Orthology | biological process |
organelle organization | Orthology | biological process |
cell differentiation | Orthology | biological process |
cell cycle | Orthology | biological process |
cell projection membrane | Orthology | cellular component |
neuron projection | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
protein kinase activity | Hs | molecular function |
protein serine/threonine kinase activity | Hs | molecular function |
G-protein coupled receptor kinase activity | Hs | molecular function |
protein kinase C binding | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
phospholipid binding | Hs | molecular function |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
cell cortex | Hs | cellular component |
protein phosphorylation | Hs | biological process |
apoptotic process | Hs | biological process |
signal transduction | Hs | biological process |
G-protein coupled receptor signaling pathway | Hs | biological process |
adenylate cyclase-modulating G-protein coupled receptor signaling pathway | Hs | biological process |
tachykinin receptor signaling pathway | Hs | biological process |
regulation of G-protein coupled receptor protein signaling pathway | Hs | biological process |
positive regulation of cell proliferation | Hs | biological process |
lipid binding | Hs | molecular function |
membrane | Hs | cellular component |
Wnt signaling pathway | Hs | biological process |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
nuclear speck | Hs | cellular component |
transferase activity | Hs | molecular function |
regulation of rhodopsin mediated signaling pathway | Hs | biological process |
dendrite | Hs | cellular component |
receptor internalization | Hs | biological process |
nuclear membrane | Hs | cellular component |
neuronal cell body | Hs | cellular component |
negative regulation of apoptotic process | Hs | biological process |
fat cell differentiation | Hs | biological process |
protein autophosphorylation | Hs | biological process |
beta-adrenergic receptor kinase activity | Hs | molecular function |
rhodopsin kinase activity | Hs | molecular function |
regulation of cell cycle | Hs | biological process |
photoreceptor disc membrane | Hs | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 522 | 0.0 |
protein kinase activity | Hs | molecular function | 522 | 0.0 |
protein serine/threonine kinase activity | Hs | molecular function | 522 | 0.0 |
G-protein coupled receptor kinase activity | Hs | molecular function | 522 | 0.0 |
protein kinase C binding | Hs | molecular function | 522 | 0.0 |
protein binding | Hs | molecular function | 522 | 0.0 |
ATP binding | Hs | molecular function | 522 | 0.0 |
phospholipid binding | Hs | molecular function | 522 | 0.0 |
nucleus | Hs | cellular component | 522 | 0.0 |
cytoplasm | Hs | cellular component | 522 | 0.0 |
cytosol | Hs | cellular component | 522 | 0.0 |
plasma membrane | Hs | cellular component | 522 | 0.0 |
cell cortex | Hs | cellular component | 486 | 7.01e-170 |
lipid binding | Hs | molecular function | 522 | 0.0 |
membrane | Hs | cellular component | 522 | 0.0 |
kinase activity | Hs | molecular function | 522 | 0.0 |
nuclear speck | Hs | cellular component | 522 | 0.0 |
transferase activity | Hs | molecular function | 522 | 0.0 |
dendrite | Hs | cellular component | 486 | 7.01e-170 |
nuclear membrane | Hs | cellular component | 522 | 0.0 |
neuronal cell body | Hs | cellular component | 486 | 7.01e-170 |
beta-adrenergic receptor kinase activity | Hs | molecular function | 522 | 0.0 |
rhodopsin kinase activity | Hs | molecular function | 486 | 7.01e-170 |
photoreceptor disc membrane | Hs | cellular component | 486 | 7.01e-170 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | SMART | molecular function | 2.4E-79 |
G-protein coupled receptor kinase activity | PRINTS | molecular function | 9.0E-17 |
ATP binding | SMART | molecular function | 2.4E-79 |
protein phosphorylation | SMART | biological process | 2.4E-79 |
signal transduction | PRINTS | biological process | 9.0E-17 |