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- Gene 'Phmamm.CG.MTP2014.S6...' >
- Gene 'Phfumi.CG.MTP2014.S6...'
Gene Card
Best human hits
ADSL; ASL; FH
Species
Unique Gene ID
Phfumi.g00007438
Gene Model ID
Phfumi.CG.MTP2014.S6638.g07438
Location
S6638:5794..10002
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Fum_hydII | PANTHER | Fumarate hydratase, class II |
Fumarase/histidase_N | Gene3D | Fumarase/histidase, N-terminal |
Fumarate_lyase_N | Pfam | Fumarate lyase, N-terminal |
Fumarate_lyase_fam | PRINTS | Fumarate lyase family |
L-Aspartase-like | SUPERFAMILY | L-Aspartase-like |
Fumarate_lyase_CS | ProSitePatterns | Fumarate lyase, conserved site |
GO Term | Annotation Origin | Type |
---|---|---|
catalytic activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
cytoplasm | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
mitochondrial matrix | Orthology | cellular component |
cytosol | Blast | cellular component |
identical protein binding | Blast | molecular function |
extracellular exosome | Orthology | cellular component |
oxidation-reduction process | Orthology | biological process |
cellular metabolic process | Orthology | biological process |
organic substance metabolic process | Orthology | biological process |
cytoplasmic part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
catalytic activity | Hs | molecular function |
fumarate hydratase activity | Hs | molecular function |
protein binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
mitochondrion | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
tricarboxylic acid cycle | Hs | biological process |
fumarate metabolic process | Hs | biological process |
malate metabolic process | Hs | biological process |
lyase activity | Hs | molecular function |
tricarboxylic acid cycle enzyme complex | Hs | cellular component |
homeostasis of number of cells within a tissue | Hs | biological process |
extracellular exosome | Hs | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
catalytic activity | Hs | molecular function | 500 | 1.63e-177 |
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity | Hs | molecular function | 37.4 | 0.009 |
argininosuccinate lyase activity | Hs | molecular function | 38.5 | 0.004 |
fumarate hydratase activity | Hs | molecular function | 500 | 1.63e-177 |
protein binding | Hs | molecular function | 500 | 1.63e-177 |
cytoplasm | Hs | cellular component | 500 | 1.63e-177 |
mitochondrion | Hs | cellular component | 500 | 1.63e-177 |
mitochondrial matrix | Hs | cellular component | 500 | 1.63e-177 |
cytosol | Hs | cellular component | 38.5 | 0.004 |
lyase activity | Hs | molecular function | 500 | 1.63e-177 |
identical protein binding | Hs | molecular function | 38.5 | 0.004 |
tricarboxylic acid cycle enzyme complex | Hs | cellular component | 500 | 1.63e-177 |
extracellular exosome | Hs | cellular component | 500 | 1.63e-177 |
(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity | Hs | molecular function | 37.4 | 0.009 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
catalytic activity | SUPERFAMILY | molecular function | 3.93E-112 |
fumarate hydratase activity | PANTHER | molecular function | 1.6E-171 |
fumarate metabolic process | PANTHER | biological process | 1.6E-171 |
tricarboxylic acid cycle enzyme complex | PANTHER | cellular component | 1.6E-171 |